This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
PAX6抗体
目录 :
AB2237
规格 :
100微克
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
文章摘录数: 24
参考文献
Lennox A, Hoye M, Jiang R, Johnson Kerner B, Suit L, Venkataramanan S, et al. Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development. Neuron. 2020;106:404-420.e8 pubmed 出版商
Imaizumi Y, Furutachi S, Watanabe T, Miya H, Kawaguchi D, Gotoh Y. Role of the imprinted allele of the Cdkn1c gene in mouse neocortical development. Sci Rep. 2020;10:1884 pubmed 出版商
Chen F, Liu X, Chen Y, Liu J, Lu H, Wang W, et al. Sphere-induced reprogramming of RPE cells into dual-potential RPE stem-like cells. EBioMedicine. 2020;52:102618 pubmed 出版商
Bredenkamp N, Yang J, Clarke J, Stirparo G, von Meyenn F, Dietmann S, et al. Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency. Stem Cell Reports. 2019;13:1083-1098 pubmed 出版商
Zeitler B, Froelich S, Marlen K, Shivak D, Yu Q, Li D, et al. Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease. Nat Med. 2019;25:1131-1142 pubmed 出版商
Xia W, Su L, Jiao J. Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress. J Cell Biol. 2018;217:3464-3479 pubmed 出版商
Xiao D, Liu X, Zhang M, Zou M, Deng Q, Sun D, et al. Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1a. Nat Commun. 2018;9:2865 pubmed 出版商
Cárdenas A, Villalba A, de Juan Romero C, Picó E, Kyrousi C, Tzika A, et al. Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Cell. 2018;174:590-606.e21 pubmed 出版商
Hegge B, Sjøttem E, Mikkola I. Generation of a PAX6 knockout glioblastoma cell line with changes in cell cycle distribution and sensitivity to oxidative stress. BMC Cancer. 2018;18:496 pubmed 出版商
Pavlaki I, Alammari F, Sun B, Clark N, Sirey T, Lee S, et al. The long non-coding RNA Paupar promotes KAP1-dependent chromatin changes and regulates olfactory bulb neurogenesis. EMBO J. 2018;37: pubmed 出版商
Bratkovic T, Modic M, Camargo Ortega G, Drukker M, Rogelj B. Neuronal differentiation induces SNORD115 expression and is accompanied by post-transcriptional changes of serotonin receptor 2c mRNA. Sci Rep. 2018;8:5101 pubmed 出版商
Pusapati G, Kong J, Patel B, Krishnan A, Sagner A, Kinnebrew M, et al. CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog. Dev Cell. 2018;44:113-129.e8 pubmed 出版商
Mellios N, Feldman D, Sheridan S, Ip J, Kwok S, Amoah S, et al. MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling. Mol Psychiatry. 2018;23:1051-1065 pubmed 出版商
Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz P, Tilly P, et al. WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017;114:E9308-E9317 pubmed 出版商
Li Y, Jiao J. Histone chaperone HIRA regulates neural progenitor cell proliferation and neurogenesis via β-catenin. J Cell Biol. 2017;216:1975-1992 pubmed 出版商
Subashini C, Dhanesh S, Chen C, Riya P, Meera V, Divya T, et al. Wnt5a is a crucial regulator of neurogenesis during cerebellum development. Sci Rep. 2017;7:42523 pubmed 出版商
Flores J, Cordero Espinoza L, Oeztuerk Winder F, Andersson Rolf A, Selmi T, Blanco S, et al. Cytosine-5 RNA Methylation Regulates Neural Stem Cell Differentiation and Motility. Stem Cell Reports. 2017;8:112-124 pubmed 出版商
Harris L, Zalucki O, Gobius I, McDonald H, Osinki J, Harvey T, et al. Transcriptional regulation of intermediate progenitor cell generation during hippocampal development. Development. 2016;143:4620-4630 pubmed
Fraser J, Essebier A, Gronostajski R, Boden M, Wainwright B, Harvey T, et al. Cell-type-specific expression of NFIX in the developing and adult cerebellum. Brain Struct Funct. 2017;222:2251-2270 pubmed 出版商
Alldredge A, Fuhrmann S. Loss of Axin2 Causes Ocular Defects During Mouse Eye Development. Invest Ophthalmol Vis Sci. 2016;57:5253-5262 pubmed 出版商
Sun J, Zhao Y, McGreal R, Cohen Tayar Y, Rockowitz S, Wilczek C, et al. Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers. Epigenetics Chromatin. 2016;9:37 pubmed 出版商
Divya T, Lalitha S, Parvathy S, Subashini C, Sanalkumar R, Dhanesh S, et al. Regulation of Tlx3 by Pax6 is required for the restricted expression of Chrnα3 in Cerebellar Granule Neuron progenitors during development. Sci Rep. 2016;6:30337 pubmed 出版商
Fame R, MacDonald J, Dunwoodie S, Takahashi E, Macklis J. Cited2 Regulates Neocortical Layer II/III Generation and Somatosensory Callosal Projection Neuron Development and Connectivity. J Neurosci. 2016;36:6403-19 pubmed 出版商
Andrews W, Davidson K, Tamamaki N, Ruhrberg C, Parnavelas J. Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice. J Comp Neurol. 2016;524:518-34 pubmed 出版商
产品信息
目录代码 :
AB2237
亚类别 :
神经科学
产品名称 :
抗PAX6抗体
产品类型 :
抗体
克隆性 :
多克隆抗体
基因编号 :
P26367
宿主名称 :
兔
抗原 :
PAX6
共轭标签 :
亲和纯化
产品描述 :
抗PAX6抗体
交叉活性 :
小鼠;大鼠;鸡
背景 :
PAX6 is the most researched of the PAX genes and appears throughout the literature as a "master control" gene for the development of eyes and other sensory organs, certain neural and epidermal tissues as well as other homologous structures, usually derived from ectodermal tissues. This transcription factor is most famous for its use in the interspecifically induced expression of ectopic eyes and is of medical importance because heterozygous mutants produce a wide spectrum of ocular defects such as Aniridia in humans. This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause aniridia as well as Peter's anomaly, both ocular diseases.
别名 :
Aniridia type II protein;paired box 6;paired box gene 6;paired box gene 6 (aniridia, keratitis);paired box homeotic gene-6
免疫原 :
KLH conjugated followed by PAX6 corresponding to the C-Terminus
特异性 :
This antibody recognizes the C-Terminus of PAX6.
包装尺寸 :
100微克
用途 :
免疫印迹;免疫细胞化学
储存 :
Stable for 1 year at 2-8ºC from date of receipt.
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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