产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
Tubulin Antibody, Detyrosinated
目录 :
AB3201
规格 :
50微克
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
默克密理博中国 产品网页
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 3c
Even A, Morelli G, Broix L, Scaramuzzino C, Turchetto S, Gladwyn Ng I, et al. ATAT1-enriched vesicles promote microtubule acetylation via axonal transport. Sci Adv. 2019;5:eaax2705 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 1b
Han S, Miyoshi K, Shikada S, Amano G, Wang Y, Yoshimura T, et al. TULP3 is required for localization of membrane-associated proteins ARL13B and INPP5E to primary cilia. Biochem Biophys Res Commun. 2018;: pubmed 出版商
  • 免疫印迹; 人类; 图 s6a
Wei J, Xu H, Meng W. Noncentrosomal microtubules regulate autophagosome transport through CAMSAP2-EB1 cross-talk. FEBS Lett. 2017;591:2379-2393 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 3
  • 免疫细胞化学; 小鼠; 1:500; 图 3
Hua K, Ferland R. Fixation methods can differentially affect ciliary protein immunolabeling. Cilia. 2017;6:5 pubmed 出版商
  • 免疫印迹; 小鼠; 1 ug/ml; 图 5
Stritt S, Nurden P, Favier R, Favier M, Ferioli S, Gotru S, et al. Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture. Nat Commun. 2016;7:11097 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 s5
Li C, Jensen V, Park K, Kennedy J, Garcia Gonzalo F, Romani M, et al. MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone. PLoS Biol. 2016;14:e1002416 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250; 图 4
Hori A, Barnouin K, Snijders A, Toda T. A non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation. EMBO Rep. 2016;17:326-37 pubmed 出版商
Nakagawa N, Plestant C, Yabuno Nakagawa K, Li J, Lee J, Huang C, et al. Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development. Neuron. 2019;: pubmed 出版商
Farías G, Fréal A, Tortosa E, Stucchi R, Pan X, Portegies S, et al. Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity. Neuron. 2019;102:184-201.e8 pubmed 出版商
Wang L, Buckley A, Spurney R. Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1). Sci Rep. 2018;8:12286 pubmed 出版商
Latremoliere A, Cheng L, DeLisle M, Wu C, Chew S, Hutchinson E, et al. Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration. Cell Rep. 2018;24:1865-1879.e9 pubmed 出版商
Qiang L, Sun X, Austin T, Muralidharan H, Jean D, Liu M, et al. Tau Does Not Stabilize Axonal Microtubules but Rather Enables Them to Have Long Labile Domains. Curr Biol. 2018;28:2181-2189.e4 pubmed 出版商
Vion A, Alt S, Klaus Bergmann A, Szymborska A, Zheng T, Perovic T, et al. Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression. J Cell Biol. 2018;217:1651-1665 pubmed 出版商
Delaney M, Malikov V, Chai Q, Zhao G, Naghavi M. Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport. Proc Natl Acad Sci U S A. 2017;114:E6932-E6941 pubmed 出版商
Ayloo S, Guedes Dias P, Ghiretti A, Holzbaur E. Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes. Mol Biol Cell. 2017;28:2543-2554 pubmed 出版商
Loukil A, Tormanen K, Sütterlin C. The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome. J Cell Biol. 2017;216:1287-1300 pubmed 出版商
Erdogan B, Cammarata G, Lee E, Pratt B, Francl A, Rutherford E, et al. The microtubule plus-end-tracking protein TACC3 promotes persistent axon outgrowth and mediates responses to axon guidance signals during development. Neural Dev. 2017;12:3 pubmed 出版商
Schober T, Magg T, Laschinger M, Rohlfs M, Linhares N, Puchalka J, et al. A human immunodeficiency syndrome caused by mutations in CARMIL2. Nat Commun. 2017;8:14209 pubmed 出版商
Castellano E, Molina Arcas M, Krygowska A, East P, Warne P, Nicol A, et al. RAS signalling through PI3-Kinase controls cell migration via modulation of Reelin expression. Nat Commun. 2016;7:11245 pubmed 出版商
产品信息
目录代码 :
AB3201
亚类别 :
Cell Structure
产品名称 :
Anti-Tubulin Antibody, Detyrosinated
产品类型 :
抗体
克隆性 :
多克隆抗体
基因编号 :
Q13509
宿主名称 :
兔
抗原 :
微管蛋白
共轭标签 :
亲和纯化
产品描述 :
Anti-Tubulin Antibody, Detyrosinated
交叉活性 :
Human;Mouse;Rat;Mammals;Green Plants;Sea Urchin
背景 :
Microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein which consists of two polypeptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22 nm diameter. Tyrosine ligase ads a C-terminal tyrosin to monomeric alpha tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton associated carboxypeptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation which is characteristic for microtubules in neuronal cells and the mitotic spindle.
别名 :
Glu Tubulin
免疫原 :
Peptide corresponding to the C-terminal of Glu tubulin.
特异性 :
The antibody specifically recognizes the detyrosinated form (Glu tubulin) of the tubulin alpha chain (Bianchi, M., 2006; Goulimari, P., 2005).
包装尺寸 :
50微克
用途 :
免疫细胞化学;免疫组化(石蜡);免疫印迹
储存 :
Stable for 6 months at -20°C in undiluted aliquots from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
更多信息或购买 :
默克密理博中国 产品网页
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
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  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
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  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.