产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
抗胶质纤维酸性蛋白抗体
目录 :
AB5541
规格 :
50微升
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
African green monkey, 人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片, immunohistochemistry - free floating section
更多信息或购买 :
文章摘录数: 58
出版应用/物种/样品/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 1b
Nam M, Han K, Lee J, Bae J, An H, Park S, et al. Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes. Exp Neurobiol. 2018;27:120-128 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 s2k
Dias D, Kim H, Holl D, Werne Solnestam B, Lundeberg J, Carlén M, et al. Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury. Cell. 2018;173:153-165.e22 pubmed 出版商
  • 免疫组化; 小鼠; 1:600; 图 2d
Paul A, Chaker Z, Doetsch F. Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis. Science. 2017;356:1383-1386 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 表 s1
Yasui T, Uezono N, Nakashima H, Noguchi H, Matsuda T, Noda Andoh T, et al. Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells. Stem Cell Reports. 2017;8:1743-1756 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 2a
Wizeman J, Mohan R. Expression of peptidylarginine deiminase 4 in an alkali injury model of retinal gliosis. Biochem Biophys Res Commun. 2017;487:134-139 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:2000; 图 1c
  • 免疫组化-石蜡切片; 人类; 1:2000; 图 1b
Sha L, Wang X, Li J, Shi X, Wu L, Shen Y, et al. Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy. J Exp Med. 2017;214:547-563 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 4a
Gadani S, Smirnov I, Smith A, Overall C, Kipnis J. Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury. J Exp Med. 2017;214:285-296 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:300; 图 5a
Yang S, Lee D, Shin J, Lee S, Baek S, Kim J, et al. Nec-1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice. EMBO Mol Med. 2017;9:61-77 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 5e
Yim N, Ryu S, Choi K, Lee K, Lee S, Choi H, et al. Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module. Nat Commun. 2016;7:12277 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 1
Almad A, Doreswamy A, Gross S, Richard J, Huo Y, Haughey N, et al. Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis. Glia. 2016;64:1154-69 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 1
  • 免疫组化; 小鼠; 1:100; 图 s4
Liu Q, Sanai N, Jin W, La Cava A, Van Kaer L, Shi F. Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation. Nat Neurosci. 2016;19:243-52 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2
Cook T, Hoekstra J, Eaton D, Zhang J. Mortalin is Expressed by Astrocytes and Decreased in the Midbrain of Parkinson's Disease Patients. Brain Pathol. 2016;26:75-81 pubmed 出版商
  • 免疫组化; 小鼠; 1:250
Meadowcroft M, Connor J, Yang Q. Cortical iron regulation and inflammatory response in Alzheimer's disease and APPSWE/PS1ΔE9 mice: a histological perspective. Front Neurosci. 2015;9:255 pubmed 出版商
  • 免疫组化; scFv; 1:1000
Rao M, Nelms B, Dong L, Salinas Rios V, Rutlin M, Gershon M, et al. Enteric glia express proteolipid protein 1 and are a transcriptionally unique population of glia in the mammalian nervous system. Glia. 2015;63:2040-2057 pubmed 出版商
  • 免疫细胞化学; 人类
Mellott A, Devarajan K, Shinogle H, Moore D, Talata Z, Laurence J, et al. Nonviral Reprogramming of Human Wharton's Jelly Cells Reveals Differences Between ATOH1 Homologues. Tissue Eng Part A. 2015;21:1795-809 pubmed 出版商
  • 免疫组化; 小鼠; 1:2000
Hohsfield L, Daschil N, Orädd G, Strömberg I, Humpel C. Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models. Mol Cell Neurosci. 2014;63:83-95 pubmed
  • 免疫组化; 人类; 1:1000
Bray A, Cevallos R, Gazarian K, Lamas M. Human dental pulp stem cells respond to cues from the rat retina and differentiate to express the retinal neuronal marker rhodopsin. Neuroscience. 2014;280:142-55 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 1
Wu Z, Guo Z, Gearing M, Chen G. Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer's [corrected] disease model. Nat Commun. 2014;5:4159 pubmed 出版商
  • 免疫组化; 小鼠
  • 免疫印迹; 小鼠
Niesman I, Schilling J, Shapiro L, Kellerhals S, Bonds J, Kleschevnikov A, et al. Traumatic brain injury enhances neuroinflammation and lesion volume in caveolin deficient mice. J Neuroinflammation. 2014;11:39 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:500
Savard A, Lavoie K, Brochu M, Grbic D, Lepage M, Gris D, et al. Involvement of neuronal IL-1? in acquired brain lesions in a rat model of neonatal encephalopathy. J Neuroinflammation. 2013;10:110 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:600
Langlet F, Mullier A, Bouret S, Prevot V, Dehouck B. Tanycyte-like cells form a blood-cerebrospinal fluid barrier in the circumventricular organs of the mouse brain. J Comp Neurol. 2013;521:3389-405 pubmed 出版商
  • immunohistochemistry - free floating section; 小鼠; 1:2000
Yoshioka N, Asou H, Hisanaga S, Kawano H. The astrocytic lineage marker calmodulin-regulated spectrin-associated protein 1 (Camsap1): phenotypic heterogeneity of newly born Camsap1-expressing cells in injured mouse brain. J Comp Neurol. 2012;520:1301-17 pubmed 出版商
  • 免疫细胞化学; African green monkey
  • 免疫细胞化学; 人类
Bloch J, Kaeser M, Sadeghi Y, Rouiller E, Redmond D, Brunet J. Doublecortin-positive cells in the adult primate cerebral cortex and possible role in brain plasticity and development. J Comp Neurol. 2011;519:775-89 pubmed 出版商
Sant Anna M, Kusuda R, Bozzo T, Bassi G, Alves Filho J, Cunha F, et al. Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization. Sci Rep. 2016;6:26955 pubmed 出版商
Daschil N, Humpel C. Green-Fluorescent Protein(+) Astrocytes Attach to Beta-Amyloid Plaques in an Alzheimer Mouse Model and Are Sensitive for Clasmatodendrosis. Front Aging Neurosci. 2016;8:75 pubmed 出版商
Lavrov I, Fox L, Shen J, Han Y, Cheng J. Gap Junctions Contribute to the Regulation of Walking-Like Activity in the Adult Mudpuppy (Necturus Maculatus). PLoS ONE. 2016;11:e0152650 pubmed 出版商
An H, Cho D, Lee S, Yang Y, Han S, Lee C. Differential Cellular Tropism of Lentivirus and Adeno-Associated Virus in the Brain of Cynomolgus Monkey. Exp Neurobiol. 2016;25:48-54 pubmed 出版商
Tse D, Lotfi P, Simons D, Sardiello M, Wu S. Electrophysiological and Histological Characterization of Rod-Cone Retinal Degeneration and Microglia Activation in a Mouse Model of Mucopolysaccharidosis Type IIIB. Sci Rep. 2015;5:17143 pubmed 出版商
Humpel C. Organotypic vibrosections from whole brain adult Alzheimer mice (overexpressing amyloid-precursor-protein with the Swedish-Dutch-Iowa mutations) as a model to study clearance of beta-amyloid plaques. Front Aging Neurosci. 2015;7:47 pubmed 出版商
Daschil N, Kniewallner K, Obermair G, Hutter Paier B, Windisch M, Marksteiner J, et al. L-type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model. Neurobiol Aging. 2015;36:1333-41 pubmed 出版商
Haidet Phillips A, Doreswamy A, Gross S, Tang X, Campanelli J, Maragakis N. Human glial progenitor engraftment and gene expression is independent of the ALS environment. Exp Neurol. 2015;264:188-99 pubmed 出版商
Kim H, Kim H, Yoon J, Kang B, Cho S, Lee S, et al. Taurine in drinking water recovers learning and memory in the adult APP/PS1 mouse model of Alzheimer's disease. Sci Rep. 2014;4:7467 pubmed 出版商
Oenarto J, Gorg B, Moos M, Bidmon H, Haussinger D. Expression of organic osmolyte transporters in cultured rat astrocytes and rat and human cerebral cortex. Arch Biochem Biophys. 2014;560:59-72 pubmed 出版商
Sawada A, Niiyama Y, Ataka K, Nagaishi K, Yamakage M, Fujimiya M. Suppression of bone marrow-derived microglia in the amygdala improves anxiety-like behavior induced by chronic partial sciatic nerve ligation in mice. Pain. 2014;155:1762-72 pubmed 出版商
Schreiber S, Drukarch B, Garz C, Niklass S, Stanaszek L, Kropf S, et al. Interplay between age, cerebral small vessel disease, parenchymal amyloid-?, and tau pathology: longitudinal studies in hypertensive stroke-prone rats. J Alzheimers Dis. 2014;42 Suppl 3:S205-15 pubmed 出版商
Li Q, Wang H, Zhou G, Jinfei M, Yan L, Zhaihu Z, et al. Production of healthy cloned pigs with neural stem cells as nuclear donors. Anim Biotechnol. 2014;25:294-305 pubmed 出版商
Myers S, Andres K, Hagg T, Whittemore S. CD36 deletion improves recovery from spinal cord injury. Exp Neurol. 2014;256:25-38 pubmed 出版商
Ataka K, Asakawa A, Nagaishi K, Kaimoto K, Sawada A, Hayakawa Y, et al. Bone marrow-derived microglia infiltrate into the paraventricular nucleus of chronic psychological stress-loaded mice. PLoS ONE. 2013;8:e81744 pubmed 出版商
Petrova R, Garcia A, Joyner A. Titration of GLI3 repressor activity by sonic hedgehog signaling is critical for maintaining multiple adult neural stem cell and astrocyte functions. J Neurosci. 2013;33:17490-505 pubmed 出版商
Daschil N, Obermair G, Flucher B, Stefanova N, Hutter Paier B, Windisch M, et al. CaV1.2 calcium channel expression in reactive astrocytes is associated with the formation of amyloid-? plaques in an Alzheimer's disease mouse model. J Alzheimers Dis. 2013;37:439-51 pubmed 出版商
Worlitzer M, Viel T, Jacobs A, Schwamborn J. The majority of newly generated cells in the adult mouse substantia nigra express low levels of Doublecortin, but their proliferation is unaffected by 6-OHDA-induced nigral lesion or Minocycline-mediated inhibition of neuroinflammation. Eur J Neurosci. 2013;38:2684-92 pubmed 出版商
Arimoto J, Wong A, Rozovsky I, Lin S, Morgan T, Finch C. Age increase of estrogen receptor-? (ER?) in cortical astrocytes impairs neurotrophic support in male and female rats. Endocrinology. 2013;154:2101-13 pubmed 出版商
Sharma V, Ling T, Rewell S, Hare D, Howells D, Kourakis A, et al. A novel population of ?-smooth muscle actin-positive cells activated in a rat model of stroke: an analysis of the spatio-temporal distribution in response to ischemia. J Cereb Blood Flow Metab. 2012;32:2055-65 pubmed 出版商
Najbauer J, Huszthy P, Barish M, Garcia E, Metz M, Myers S, et al. Cellular host responses to gliomas. PLoS ONE. 2012;7:e35150 pubmed 出版商
Bao Y, Qin L, Kim E, Bhosle S, Guo H, Febbraio M, et al. CD36 is involved in astrocyte activation and astroglial scar formation. J Cereb Blood Flow Metab. 2012;32:1567-77 pubmed 出版商
Stephan J, Haack N, Kafitz K, Durry S, Koch D, Hochstrate P, et al. Kir4.1 channels mediate a depolarization of hippocampal astrocytes under hyperammonemic conditions in situ. Glia. 2012;60:965-78 pubmed 出版商
Guenther C, Windelborn J, Tubon T, Yin J, Mitchell G. Increased atypical PKC expression and activity in the phrenic motor nucleus following cervical spinal injury. Exp Neurol. 2012;234:513-20 pubmed 出版商
Zabierowski S, Baubet V, Himes B, Li L, Fukunaga Kalabis M, Patel S, et al. Direct reprogramming of melanocytes to neural crest stem-like cells by one defined factor. Stem Cells. 2011;29:1752-62 pubmed 出版商
Lopez N, Krzyzaniak M, Blow C, Putnam J, Ortiz Pomales Y, Hageny A, et al. Ghrelin prevents disruption of the blood-brain barrier after traumatic brain injury. J Neurotrauma. 2012;29:385-93 pubmed 出版商
Han K, Mannaioni G, Hamill C, Lee J, Junge C, Lee C, et al. Activation of protease activated receptor 1 increases the excitability of the dentate granule neurons of hippocampus. Mol Brain. 2011;4:32 pubmed 出版商
Gray S, Matagne V, Bachaboina L, Yadav S, Ojeda S, Samulski R. Preclinical differences of intravascular AAV9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primates. Mol Ther. 2011;19:1058-69 pubmed 出版商
Lodygensky G, West T, Moravec M, Back S, Dikranian K, Holtzman D, et al. Diffusion characteristics associated with neuronal injury and glial activation following hypoxia-ischemia in the immature brain. Magn Reson Med. 2011;66:839-45 pubmed 出版商
Ibrahim A, El Remessy A, Matragoon S, Zhang W, Patel Y, Khan S, et al. Retinal microglial activation and inflammation induced by amadori-glycated albumin in a rat model of diabetes. Diabetes. 2011;60:1122-33 pubmed 出版商
Yoshioka N, Kimura Kuroda J, Saito T, Kawamura K, Hisanaga S, Kawano H. Small molecule inhibitor of type I transforming growth factor-? receptor kinase ameliorates the inhibitory milieu in injured brain and promotes regeneration of nigrostriatal dopaminergic axons. J Neurosci Res. 2011;89:381-93 pubmed 出版商
Wall M, Eason R, Dale N. Biosensor measurement of purine release from cerebellar cultures and slices. Purinergic Signal. 2010;6:339-48 pubmed 出版商
Yoshioka N, Hisanaga S, Kawano H. Suppression of fibrotic scar formation promotes axonal regeneration without disturbing blood-brain barrier repair and withdrawal of leukocytes after traumatic brain injury. J Comp Neurol. 2010;518:3867-81 pubmed 出版商
Lodygensky G, West T, Stump M, Holtzman D, Inder T, Neil J. In vivo MRI analysis of an inflammatory injury in the developing brain. Brain Behav Immun. 2010;24:759-67 pubmed 出版商
Doering J, Kane K, Hsiao Y, Yao C, Shi B, Slowik A, et al. Species differences in the expression of Ahi1, a protein implicated in the neurodevelopmental disorder Joubert syndrome, with preferential accumulation to stigmoid bodies. J Comp Neurol. 2008;511:238-56 pubmed 出版商
产品信息
目录代码 :
AB5541
亚类别 :
神经科学
产品名称 :
抗胶质纤维酸性蛋白抗体
产品类型 :
抗体
克隆性 :
多克隆抗体
基因编号 :
P14136
宿主名称 :
抗原 :
胶质纤维酸性蛋白
共轭标签 :
亲和纯化
产品描述 :
抗胶质纤维酸性蛋白抗体
交叉活性 :
人类;小鼠;大鼠;牛;猪
背景 :
Glial fibrillary acidic protein (GFAP) is a class-III intermediate filament. Type III intermediate filaments contain three domains, the most conserved of which is the rod domain. The specific sequence for this region of the protein may differ between the different intermediate filament genes for type III proteins, but the structure of the protein is highly conserved. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
别名 :
GFAP
免疫原 :
纯化牛GFAP
特异性 :
Glial fibrillary acidic protein (GFAP). Reacts with both native and recombinant protein.
包装尺寸 :
50微升
用途 :
免疫细胞化学;免疫组化;免疫组化(石蜡);免疫印迹
储存 :
Stable for 1 year at -20°C in undiluted aliquots from date of receipt. Do not store in a self-defrosting freezer. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
更多信息或购买 :
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
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View all the new antibodies at www.emdmillipore.com.