产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
小鼠I型胶原抗体
目录 :
AB765P
规格 :
100微克
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 放射免疫分析法, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:100
Luxan G, Stewen J, Díaz N, Kato K, Maney S, Aravamudhan A, et al. Endothelial EphB4 maintains vascular integrity and transport function in adult heart. elife. 2019;8: pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 2s1c
Bayer S, Grither W, Brenot A, Hwang P, Barcus C, Ernst M, et al. DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs. elife. 2019;8: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100–1:250
Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed 出版商
  • 免疫组化; 小鼠; 图 9a
Saxon J, Baer D, Barton J, Hawkins T, Wu B, Trusk T, et al. BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling. Dev Biol. 2017;430:113-128 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s7a
Olivares O, Mayers J, Gouirand V, Torrence M, Gicquel T, Borge L, et al. Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions. Nat Commun. 2017;8:16031 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Gocheva V, Naba A, Bhutkar A, Guardia T, Miller K, Li C, et al. Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. Proc Natl Acad Sci U S A. 2017;114:E5625-E5634 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 s3b
  • 免疫细胞化学; 小鼠; 图 s4a
McKee K, Crosson S, Meinen S, Reinhard J, Ruegg M, Yurchenco P. Chimeric protein repair of laminin polymerization ameliorates muscular dystrophy phenotype. J Clin Invest. 2017;127:1075-1089 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3c
Chowdhury A, Hasselbach L, Echtermeyer F, Jyotsana N, Theilmeier G, Herzog C. Fibulin-6 regulates pro-fibrotic TGF-β responses in neonatal mouse ventricular cardiac fibroblasts. Sci Rep. 2017;7:42725 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 5c
Ishikawa Y, Ito S, Nagata K, Sakai L, Bachinger H. Intracellular mechanisms of molecular recognition and sorting for transport of large extracellular matrix molecules. Proc Natl Acad Sci U S A. 2016;113:E6036-E6044 pubmed
  • 免疫组化-石蜡切片; 小鼠; 1:100; 表 1
  • 免疫印迹; 小鼠; 1:1000; 表 2
Muñoz Félix J, Pérez Roque L, Núñez Gómez E, Oujo B, Arevalo M, Ruiz Remolina L, et al. Overexpression of the short endoglin isoform reduces renal fibrosis and inflammation after unilateral ureteral obstruction. Biochim Biophys Acta. 2016;1862:1801-14 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 12
Ufimtseva E. Differences between Mycobacterium-Host Cell Relationships in Latent Tuberculous Infection of Mice Ex Vivo and Mycobacterial Infection of Mouse Cells In Vitro. J Immunol Res. 2016;2016:4325646 pubmed 出版商
Omari S, Makareeva E, Roberts Pilgrim A, Mirigian L, Jarnik M, Ott C, et al. Noncanonical autophagy at ER exit sites regulates procollagen turnover. Proc Natl Acad Sci U S A. 2018;115:E10099-E10108 pubmed 出版商
Rayagiri S, Ranaldi D, Raven A, Mohamad Azhar N, Lefebvre O, Zammit P, et al. Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal. Nat Commun. 2018;9:1075 pubmed 出版商
Ito S, Ogawa K, Takeuchi K, Takagi M, Yoshida M, Hirokawa T, et al. A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis. J Biol Chem. 2017;292:20076-20085 pubmed 出版商
产品信息
目录代码 :
AB765P
亚类别 :
Cell Structure
产品名称 :
抗小鼠I型胶原抗体
产品类型 :
抗体
克隆性 :
多克隆抗体
基因编号 :
P02452
宿主名称 :
抗原 :
小鼠I型胶原
共轭标签 :
纯化
抗体亚型 :
IgG
产品描述 :
抗小鼠I型胶原抗体
交叉活性 :
小鼠
背景 :
Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% of the total protein content. It is one of the long, fibrous structural proteins whose functions are quite different from those of globular proteins such as enzymes; tough bundles of collagen called collagen fibers are a major component of the extracellular matrix that supports most tissues and gives cells structure from the outside, but collagen is also found inside certain cells. Collagen has great tensile strength, and is the main component of fascia, cartilage, ligaments, tendons, bone and teeth. Along with soft keratin, it is responsible for skin strength and elasticity, and its degradation leads to wrinkles that accompany aging. It strengthens blood vessels and plays a role in tissue development. It is present in the cornea and lens of the eye in crystalline form. Collagen occurs in many places throughout the body. There are 12 types of collagen described in literature. Collagen Type 1: This is the most abundant collagen of the human body. It is present in scar tissue, the end product when tissue heals by repair. It is found in tendons, the endomysium of myofibrils and the organic part of bone. Collagen Type 4: It is present in basal lamina and the eye lens. Also serves as part of the filtration system in capillaries and the glomeruli of nephron in the kidney.
免疫原 :
Collagen Type I extracted and purified from mouse skin.
特异性 :
识别小鼠I型胶原
包装尺寸 :
100微克
用途 :
酶联免疫吸附测定;免疫组化;放射免疫分析法;免疫印迹
储存 :
Stable for 1 year at -20ºC from date of receipt.
更多信息或购买 :
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
  • • Cancer
  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.