产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
磷酸甘油醛脱氢酶抗体
目录 :
ABS16
规格 :
100微克
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹
更多信息或购买 :
文章摘录数: 29
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 s2a
Ebright R, Lee S, Wittner B, Niederhoffer K, Nicholson B, Bardia A, et al. Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis. Science. 2020;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 1d
Collier M, Alderson T, de Villiers C, Nicholls D, Gastall H, Allison T, et al. HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C. Sci Adv. 2019;5:eaav8421 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 s4
Gómez Fernández P, Urtasun A, Paton A, Paton J, Borrego F, Dersh D, et al. Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response. Front Immunol. 2018;9:2934 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 1b
Szappanos D, Tschismarov R, Perlot T, Westermayer S, Fischer K, Platanitis E, et al. The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity. PLoS Pathog. 2018;14:e1007397 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Nowacka J, Baumgartner C, Pelorosso C, Roth M, Zuber J, Baccarini M. MEK1 is required for the development of NRAS-driven leukemia. Oncotarget. 2016;7:80113-80130 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Raguz J, Jerić I, Niault T, Nowacka J, Kuzet S, Rupp C, et al. Epidermal RAF prevents allergic skin disease. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3b
Song J, Wang Y, Teng M, Zhang S, Yin M, Lu J, et al. Cordyceps militaris induces tumor cell death via the caspase?dependent mitochondrial pathway in HepG2 and MCF?7 cells. Mol Med Rep. 2016;13:5132-40 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 2
Polanco J, Scicluna B, Hill A, Götz J. Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner. J Biol Chem. 2016;291:12445-66 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Liu H, Zhang S, Zhao L, Zhang Y, Li Q, Chai X, et al. Resveratrol Enhances Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells through Inhibiting Canonical WNT Signal Pathway and Enhancing Serum Response Factor-miR-1 Axis. Stem Cells Int. 2016;2016:2524092 pubmed 出版商
Platanitis E, Demiröz D, Schneller A, Fischer K, Capelle C, Hartl M, et al. A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription. Nat Commun. 2019;10:2921 pubmed 出版商
Brayford S, Kenny F, Hiratsuka T, Serna Morales E, Yolland L, Luchici A, et al. Heterotypic contact inhibition of locomotion can drive cell sorting between epithelial and mesenchymal cell populations. J Cell Sci. 2019;132: pubmed 出版商
Sparrow A, Sievert K, Patel S, Chang Y, Broyles C, Brook F, et al. Measurement of Myofilament-Localized Calcium Dynamics in Adult Cardiomyocytes and the Effect of Hypertrophic Cardiomyopathy Mutations. Circ Res. 2019;124:1228-1239 pubmed 出版商
Wild T, Budzowska M, Hellmuth S, Eibes S, Karemore G, Barisic M, et al. Deletion of APC7 or APC16 Allows Proliferation of Human Cells without the Spindle Assembly Checkpoint. Cell Rep. 2018;25:2317-2328.e5 pubmed 出版商
Daga N, Eicher S, Kannan A, Casanova A, Low S, Kreibich S, et al. Growth-restricting effects of siRNA transfections: a largely deterministic combination of off-target binding and hybridization-independent competition. Nucleic Acids Res. 2018;46:9309-9320 pubmed 出版商
Nguyen H, Leong W, Li W, Reddy P, Sullivan J, Walter M, et al. Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes. Cancer Res. 2018;78:5363-5374 pubmed 出版商
Wang X, Qu Y, Zhang Y, Li S, Sun Y, Chen Z, et al. Antifatigue Potential Activity of Sarcodon imbricatus in Acute Excise-Treated and Chronic Fatigue Syndrome in Mice via Regulation of Nrf2-Mediated Oxidative Stress. Oxid Med Cell Longev. 2018;2018:9140896 pubmed 出版商
Li C, Götz J. Pyk2 is a Novel Tau Tyrosine Kinase that is Regulated by the Tyrosine Kinase Fyn. J Alzheimers Dis. 2018;64:205-221 pubmed 出版商
Shi J, Surma M, Wei L. Disruption of ROCK1 gene restores autophagic flux and mitigates doxorubicin-induced cardiotoxicity. Oncotarget. 2018;9:12995-13008 pubmed 出版商
Campbell M, Watanabe T, Nakano K, Davis R, Lyu Y, Tepper C, et al. KSHV episomes reveal dynamic chromatin loop formation with domain-specific gene regulation. Nat Commun. 2018;9:49 pubmed 出版商
Maphis N, Jiang S, Binder J, Wright C, Gopalan B, Lamb B, et al. Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology. Front Mol Neurosci. 2017;10:69 pubmed 出版商
Teveroni E, Pellegrino M, Sacconi S, Calandra P, Cascino I, Farioli Vecchioli S, et al. Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity. J Clin Invest. 2017;127:1531-1545 pubmed 出版商
Bodea L, Evans H, Van der Jeugd A, Ittner L, Delerue F, Kril J, et al. Accelerated aging exacerbates a pre-existing pathology in a tau transgenic mouse model. Aging Cell. 2017;16:377-386 pubmed 出版商
Henrich C. A Microplate-Based Nonradioactive Protein Synthesis Assay: Application to TRAIL Sensitization by Protein Synthesis Inhibitors. PLoS ONE. 2016;11:e0165192 pubmed 出版商
Li S, Zhang H, Du Z, Li C, An M, Zong Z, et al. Induction of epithelial-mesenchymal transition (EMT) by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells. Oncotarget. 2016;7:70364-70377 pubmed 出版商
Jacqueroud L, Bouard C, Richard G, Payen L, Devouassoux Shisheboran M, Spicer D, et al. The Heterodimeric TWIST1-E12 Complex Drives the Oncogenic Potential of TWIST1 in Human Mammary Epithelial Cells. Neoplasia. 2016;18:317-327 pubmed 出版商
Hayward S, Wilson C, Kidambi S. Hyaluronic acid-conjugated liposome nanoparticles for targeted delivery to CD44 overexpressing glioblastoma cells. Oncotarget. 2016;7:34158-71 pubmed 出版商
Sugihara T, Nakagawa S, Sasajima Y, Ichinose T, Hiraike H, Kondo F, et al. Loss of the cell polarity determinant human Discs-large is a novel molecular marker of nodal involvement and poor prognosis in endometrial cancer. Br J Cancer. 2016;114:1012-8 pubmed 出版商
Boyer J, Baron M, Constantin A, Degboé Y, Cantagrel A, Davignon J. Anti-TNF certolizumab pegol induces antioxidant response in human monocytes via reverse signaling. Arthritis Res Ther. 2016;18:56 pubmed 出版商
Silva M, Nascimento T, Pereira M, Siqueira A, Brum P, Jaeger R, et al. β2-Adrenoceptor is involved in connective tissue remodeling in regenerating muscles by decreasing the activity of MMP-9. Cell Tissue Res. 2016;365:173-86 pubmed 出版商
产品信息
目录代码 :
ABS16
亚类别 :
Cell Signaling
产品名称 :
抗磷酸甘油醛脱氢酶抗体
产品类型 :
抗体
克隆性 :
多克隆抗体
基因编号 :
P04406
宿主名称 :
抗原 :
磷酸甘油醛脱氢酶
共轭标签 :
亲和纯化
产品描述 :
抗磷酸甘油醛脱氢酶抗体
交叉活性 :
人类;小鼠;大鼠;牛;豚鼠
背景 :
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is an ubiquitous glycolytic enzyme present in moderately high levels in almost all tissues. As a 'house-keeping' enzyme, it catalyzes the synthesis of 1,3-biphosphoglycerate, a "high energy" intermediate used for the synthesis of ATP. Besides its cytoplasmic action in metabolism it is also involved in the initial stages of apoptosis or oxidative stress response where GAPDH is translocated to the nucleus. Such actions may reflect the role of GAPDH in DNA repair or as one nuclear carrier for apoptotic molecules. GAPDH has also been found to bind specifically to proteins implicated in the pathogenesis of a variety of neurodegenerative disorders including the beta-amyloid precursor protein and the huntingtin protein where decreased function of GAPDH is associated with Alzheimer's and Huntington's disease fibroblasts. GAPDH has also been identified as a potential target for nitric oxide (NO)-mediated cellular toxicity. The complete and functional enzyme is a tetramer with each of four identical subunits occupying the vertex of a tetrahedron. Binding domains also include one principally interacting with NAD+ and another interacting with glyceraldehyde 3-phosphate (GAP).
别名 :
glyceraldehyde 3-phosphate dehydrogenase;aging-associated gene 9 protein;glyceraldehyde-3-phosphate dehydrogenase
免疫原 :
GST-tagged recombinant protein corresponding to the C-terminus of human GAPDH.
特异性 :
This antibody recognizes GAPDH at the C-terminus.
包装尺寸 :
100微克
用途 :
西方墨点法
储存 :
收到之日起在2-8℃稳定1年
更多信息或购买 :
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
  • • Cancer
  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.