产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
磷酸甘油醛脱氢酶小鼠单克隆抗体(6C5)
目录 :
CB1001-500微克
规格 :
500微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, 犬
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
默克密理博中国 产品网页
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1500; 图 s8c
Mukhtar T, Breda J, Grison A, Karimaddini Z, Grobecker P, Iber D, et al. Tead transcription factors differentially regulate cortical development. Sci Rep. 2020;10:4625 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 s2g
Moradi M, Sivadasan R, Saal L, Lüningschrör P, Dombert B, Rathod R, et al. Differential roles of α-, β-, and γ-actin in axon growth and collateral branch formation in motoneurons. J Cell Biol. 2017;216:793-814 pubmed 出版商
  • 免疫印迹; 犬; 1:1000; 图 1d
Gray M, Lee S, McDowell A, Erskine M, Loh Q, Grice O, et al. Dual targeting of EGFR and ERBB2 pathways produces a synergistic effect on cancer cell proliferation and migration in vitro. Vet Comp Oncol. 2017;15:890-909 pubmed 出版商
  • 免疫印迹; 小鼠; 1:4000; 图 13
Schmitt D, Funk N, Blum R, Asan E, Andersen L, Rülicke T, et al. Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons. Histochem Cell Biol. 2016;146:489-512 pubmed 出版商
  • 免疫印迹; 大鼠; 1:10,000
Mavlyutov T, Duellman T, Kim H, Epstein M, Leese C, Davletov B, et al. Sigma-1 receptor expression in the dorsal root ganglion: Reexamination using a highly specific antibody. Neuroscience. 2016;331:148-57 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Freund P, Porpaczy E, Le T, Gruber M, Pausz C, Staber P, et al. Cannabinoid Receptors Are Overexpressed in CLL but of Limited Potential for Therapeutic Exploitation. PLoS ONE. 2016;11:e0156693 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Jennewein L, Ronellenfitsch M, Antonietti P, Ilina E, Jung J, Stadel D, et al. Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas. Oncotarget. 2016;7:20016-32 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000; 图 3
  • 免疫印迹; 小鼠; 1:20,000; 图 5
Takabatake Y, Oxvig C, Nagi C, Adelson K, Jaffer S, Schmidt H, et al. Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer. EMBO Mol Med. 2016;8:388-406 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Jia L, Li B, Yu H. The Bub1-Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation. Nat Commun. 2016;7:10818 pubmed 出版商
  • 免疫印迹; 人类; 1:2500; 图 2
Jansen J, Timal S, van Scherpenzeel M, Michelakakis H, Vicogne D, Ashikov A, et al. TMEM199 Deficiency Is a Disorder of Golgi Homeostasis Characterized by Elevated Aminotransferases, Alkaline Phosphatase, and Cholesterol and Abnormal Glycosylation. Am J Hum Genet. 2016;98:322-30 pubmed 出版商
  • 免疫印迹; 人类; 图 1
  • 免疫印迹; 小鼠; 图 1
Abu Odeh M, Hereema N, Aqeilan R. WWOX modulates the ATR-mediated DNA damage checkpoint response. Oncotarget. 2016;7:4344-55 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000
Kraushar M, Viljetić B, Wijeratne H, Thompson K, Jiao X, Pike J, et al. Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes. J Neurosci. 2015;35:10911-26 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Liechtenstein T, Perez Janices N, Blanco Luquin I, Goyvaerts C, Schwarze J, Dufait I, et al. Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy. Oncoimmunology. 2014;3:e945378 pubmed
  • 免疫印迹; 人类; 1:1000; 图 3
Gennarino V, Singh R, White J, De Maio A, Han K, Kim J, et al. Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels. Cell. 2015;160:1087-98 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Guerrero A, Iglesias C, Raguz S, Floridia E, Gil J, Pombo C, et al. The cerebral cavernous malformation 3 gene is necessary for senescence induction. Aging Cell. 2015;14:274-83 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 4
Kurz A, Double K, Lastres Becker I, Tozzi A, Tantucci M, Bockhart V, et al. A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice. PLoS ONE. 2010;5:e11464 pubmed 出版商
Li D, Musante V, Zhou W, Picciotto M, Nairn A. Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons. J Biol Chem. 2018;293:11179-11194 pubmed 出版商
Gennarino V, Palmer E, McDonell L, Wang L, Adamski C, Koire A, et al. A Mild PUM1 Mutation Is Associated with Adult-Onset Ataxia, whereas Haploinsufficiency Causes Developmental Delay and Seizures. Cell. 2018;172:924-936.e11 pubmed 出版商
Zhu L, Yang J, Bromberger T, Holly A, Lu F, Liu H, et al. Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation. Nat Commun. 2017;8:1744 pubmed 出版商
Gennarino V, Alcott C, Chen C, Chaudhury A, Gillentine M, Rosenfeld J, et al. NUDT21-spanning CNVs lead to neuropsychiatric disease and altered MeCP2 abundance via alternative polyadenylation. elife. 2015;4: pubmed 出版商
产品信息
目录代码 :
CB1001-500微克
类别 :
抗体
亚类别 :
Cell Structure
产品名称 :
抗磷酸甘油醛脱氢酶小鼠单克隆抗体(6C5)
产品类型 :
抗体
克隆性 :
单克隆
基因编号 :
2597 (Hu), 100043349 (Ms), 500983 689689 24383 685186 (Rt)
宿主名称 :
M
克隆 :
6C5
共轭标签 :
纯化
抗体亚型 :
IgG1
产品描述 :
抗磷酸甘油醛脱氢酶小鼠单克隆抗体(6C5)
交叉活性 :
Canine, Chicken, Fish, Frog, Human, Mouse, Porcine, Rabbit, Rat
背景 :
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is one of the key enzymes involved in glycolysis. GAPDH is comprised of four ~36 kDa subunits with a total molecular weight of ~146 kDa. Besides functioning as a glycolytic enzyme in cytoplasm, mammalian GAPDH is also involved in a great number of intracellular processes such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication and DNA repair. Recently, findings have been made concerning the role of GAPDH in differentpathologies including prostate cancer progression, programmed neuronal cell death, and age-related neuronal diseases such as Alzheimer’s Disease and Huntington’s Disease. While GAPDH is constitutively expressed in almost all tissues at high levels, there are some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types.
别名 :
G3PD, G3PDH, GAPD, 磷酸甘油醛脱氢酶, 甘油醛3脱氢酶, NUCLEAR尿嘧啶脱氧核糖核酸GLYCOSYLASE, 甘油醛3脱氢酶
免疫原 :
纯化, 兔肌肉
特异性 :
Recognizes the ~146 kDa GAPDH protein under non-reducing conditions and the ~36 kDa monomeric subunits under reducing conditions.
包装尺寸 :
500微克
用途 :
酶联免疫吸附测定, 免疫印迹, 细胞化学
储存 :
Following initial use, aliquot and freeze (-20°C) for long-term storage if desired. Avoid freeze/thaw.
更多信息或购买 :
默克密理博中国 产品网页
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
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