产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
抗谷氨酰胺合成抗体, 克隆GS-6
目录 :
MAB302
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
GS-6
反应物种 :
medaka, African green monkey, Gallotia galloti, lepidosaurs, 人类, 小鼠, 大鼠, 斑马鱼, 果蝇, common platanna
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片, immunohistochemistry - free floating section
更多信息或购买 :
文章摘录数: 202
出版应用/物种/样品/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:300; 图 7a
Fairchild C, Hino K, Han J, Miltner A, Peinado Allina G, Brown C, et al. RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018;145: pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 4a
Janda C, Dang L, You C, Chang J, de Lau W, Zhong Z, et al. Surrogate Wnt agonists that phenocopy canonical Wnt and ?-catenin signalling. Nature. 2017;545:234-237 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 6
Theofilas P, Steinhäuser C, Theis M, Derouiche A. Morphological study of a connexin 43-GFP reporter mouse highlights glial heterogeneity, amacrine cells, and olfactory ensheathing cells. J Neurosci Res. 2017;95:2182-2194 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 4
Weng C, Ding M, Chang L, Ren M, Zhang H, Lu Z, et al. Ankfy1 is dispensable for neural stem/precursor cell development. Neural Regen Res. 2016;11:1804-1809 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 6g
Schäfer N, Grosche A, Reinders J, Hauck S, Pouw R, Kuijpers T, et al. Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases. Front Immunol. 2016;7:542 pubmed
  • 免疫细胞化学; 小鼠; 1:100; 图 s2a
Roche S, Wyse Jackson A, Gomez Vicente V, Lax P, Ruiz Lopez A, Byrne A, et al. Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling. PLoS ONE. 2016;11:e0165197 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 4c
Kubota N, Kubota T, Kajiwara E, Iwamura T, Kumagai H, Watanabe T, et al. Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity. Nat Commun. 2016;7:12977 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Cudré Cung H, Zavadakova P, Do Vale Pereira S, Remacle N, Henry H, Ivanisevic J, et al. Ammonium accumulation is a primary effect of 2-methylcitrate exposure in an in vitro model for brain damage in methylmalonic aciduria. Mol Genet Metab. 2016;119:57-67 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 2
Laramée M, Smolders K, Hu T, Bronchti G, Boire D, Arckens L. Congenital Anophthalmia and Binocular Neonatal Enucleation Differently Affect the Proteome of Primary and Secondary Visual Cortices in Mice. PLoS ONE. 2016;11:e0159320 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 4
Simmons A, Bloomsburg S, Billingslea S, Merrill M, Li S, Thomas M, et al. Pou4f2 knock-in Cre mouse: A multifaceted genetic tool for vision researchers. Mol Vis. 2016;22:705-17 pubmed
  • 免疫组化; 小鼠; 1:1000; 图 4
Hughes S, Rodgers J, Hickey D, Foster R, Peirson S, Hankins M. Characterisation of light responses in the retina of mice lacking principle components of rod, cone and melanopsin phototransduction signalling pathways. Sci Rep. 2016;6:28086 pubmed 出版商
  • 免疫组化; medaka; 1:500; 图 2
Lust K, Sinn R, Pérez Saturnino A, Centanin L, Wittbrodt J. De novo neurogenesis by targeted expression of atoh7 to Müller glia cells. Development. 2016;143:1874-83 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 1g
Del Debbio C, Mir Q, Parameswaran S, Mathews S, Xia X, Zheng L, et al. Notch Signaling Activates Stem Cell Properties of Müller Glia through Transcriptional Regulation and Skp2-mediated Degradation of p27Kip1. PLoS ONE. 2016;11:e0152025 pubmed 出版商
  • 免疫组化; African green monkey; 1:500; 图 4
  • 免疫组化; 小鼠; 1:500; 图 4
Bouskila J, Javadi P, Elkrief L, Casanova C, Bouchard J, Ptito M. A Comparative Analysis of the Endocannabinoid System in the Retina of Mice, Tree Shrews, and Monkeys. Neural Plast. 2016;2016:3127658 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 7
Pak J, Lee E, CRAFT C. The retinal phenotype of Grk1-/- is compromised by a Crb1 rd8 mutation. Mol Vis. 2015;21:1281-94 pubmed
  • 免疫细胞化学; 小鼠; 1:100; 图 3
Beaudet M, Yang Q, Cadau S, Blais M, Bellenfant S, Gros Louis F, et al. High yield extraction of pure spinal motor neurons, astrocytes and microglia from single embryo and adult mouse spinal cord. Sci Rep. 2015;5:16763 pubmed 出版商
  • 免疫组化; common platanna
Luehders K, Sasai N, Davaapil H, Kurosawa Yoshida M, Hiura H, Brah T, et al. The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway. Development. 2015;142:3351-61 pubmed 出版商
  • 免疫组化; 斑马鱼; 1:50; 图 2c
MacDonald R, Randlett O, Oswald J, Yoshimatsu T, Franze K, Harris W. Müller glia provide essential tensile strength to the developing retina. J Cell Biol. 2015;210:1075-83 pubmed 出版商
  • 免疫组化; 小鼠; 图 7
Du M, Otalora L, Martin A, Moiseyev G, Vanlandingham P, Wang Q, et al. Transgenic Mice Overexpressing Serum Retinol-Binding Protein Develop Progressive Retinal Degeneration through a Retinoid-Independent Mechanism. Mol Cell Biol. 2015;35:2771-89 pubmed 出版商
  • 免疫印迹; 果蝇; 1:1000
Strauss A, Kawasaki F, Ordway R. A Distinct Perisynaptic Glial Cell Type Forms Tripartite Neuromuscular Synapses in the Drosophila Adult. PLoS ONE. 2015;10:e0129957 pubmed 出版商
  • 免疫组化; 小鼠; 1:5000
Jin K, Jiang H, Xiao D, Zou M, Zhu J, Xiang M. Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis. Mol Brain. 2015;8:28 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 8
Agca C, Boldt K, Gubler A, Meneau I, Corpet A, Samardzija M, et al. Expression of leukemia inhibitory factor in Müller glia cells is regulated by a redox-dependent mRNA stability mechanism. BMC Biol. 2015;13:30 pubmed 出版商
  • 免疫组化; 斑马鱼; 1:200; 图 4
Gramage E, D Cruz T, Taylor S, Thummel R, Hitchcock P. Midkine-a protein localization in the developing and adult retina of the zebrafish and its function during photoreceptor regeneration. PLoS ONE. 2015;10:e0121789 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Coorey N, Shen W, Zhu L, Gillies M. Differential Expression of IL-6/gp130 Cytokines, Jak-STAT Signaling and Neuroprotection After Müller Cell Ablation in a Transgenic Mouse Model. Invest Ophthalmol Vis Sci. 2015;56:2151-61 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:5000; 图 4j
Zou M, Luo H, Xiang M. Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015;244:86-97 pubmed 出版商
  • 免疫组化; 小鼠; 1:200
Griemsmann S, Höft S, Bedner P, Zhang J, von Staden E, Beinhauer A, et al. Characterization of Panglial Gap Junction Networks in the Thalamus, Neocortex, and Hippocampus Reveals a Unique Population of Glial Cells. Cereb Cortex. 2015;25:3420-33 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:300; 图 1
Dharmarajan S, Gurel Z, Wang S, Sorenson C, Sheibani N, Belecky Adams T. Bone morphogenetic protein 7 regulates reactive gliosis in retinal astrocytes and Müller glia. Mol Vis. 2014;20:1085-108 pubmed
  • 免疫组化; medaka; 1:500
Sinn R, Peravali R, Heermann S, Wittbrodt J. Differential responsiveness of distinct retinal domains to Atoh7. Mech Dev. 2014;133:218-29 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Shen W, Chung S, Irhimeh M, Li S, Lee S, Gillies M. Systemic administration of erythropoietin inhibits retinopathy in RCS rats. PLoS ONE. 2014;9:e104759 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500
Joly S, Jordi N, Schwab M, Pernet V. The Ephrin receptor EphA4 restricts axonal sprouting and enhances branching in the injured mouse optic nerve. Eur J Neurosci. 2014;40:3021-31 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Ho T, Vessey K, Fletcher E. Immunolocalization of the P2X4 receptor on neurons and glia in the mammalian retina. Neuroscience. 2014;277:55-71 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:1000
Oklinski M, Lim J, Choi H, Oklinska P, Skowronski M, Kwon T. Immunolocalization of Water Channel Proteins AQP1 and AQP4 in Rat Spinal Cord. J Histochem Cytochem. 2014;62:598-611 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:1,000
Vessey K, Greferath U, Aplin F, Jobling A, Phipps J, Ho T, et al. Adenosine triphosphate-induced photoreceptor death and retinal remodeling in rats. J Comp Neurol. 2014;522:2928-50 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Ippolito J, Piwnica Worms D. A fluorescence-coupled assay for gamma aminobutyric acid (GABA) reveals metabolic stress-induced modulation of GABA content in neuroendocrine cancer. PLoS ONE. 2014;9:e88667 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠
Kermorvant Duchemin E, Pinel A, Lavalette S, Lenne D, Raoul W, Calippe B, et al. Neonatal hyperglycemia inhibits angiogenesis and induces inflammation and neuronal degeneration in the retina. PLoS ONE. 2013;8:e79545 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500
  • 免疫细胞化学; 小鼠; 1:500
  • 免疫印迹; 小鼠; 1:1000
Brison E, Jacomy H, Desforges M, Talbot P. Novel treatment with neuroprotective and antiviral properties against a neuroinvasive human respiratory virus. J Virol. 2014;88:1548-63 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500
  • 免疫细胞化学; 小鼠
Brunne B, FRANCO S, Bouché E, Herz J, Howell B, Pahle J, et al. Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice. Glia. 2013;61:1347-63 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200-1:400
Pernet V, Joly S, Dalkara D, Jordi N, Schwarz O, Christ F, et al. Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve. Neurobiol Dis. 2013;51:202-13 pubmed 出版商
  • 免疫组化-冰冻切片; 斑马鱼; 1:800
Lindsey B, Darabie A, Tropepe V. The cellular composition of neurogenic periventricular zones in the adult zebrafish forebrain. J Comp Neurol. 2012;520:2275-316 pubmed 出版商
  • 免疫组化-石蜡切片; Gallotia galloti; 1:500
Romero Alemán M, Monzon Mayor M, Santos E, Lang D, Yanes C. Neuronal and glial differentiation during lizard (Gallotia galloti) visual system ontogeny. J Comp Neurol. 2012;520:2163-84 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000
Nasonkin I, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A. Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011;519:1914-30 pubmed 出版商
  • immunohistochemistry - free floating section; 小鼠; 1:500
Kim E, Hori K, Wyckoff A, Dickel L, Koundakjian E, Goodrich L, et al. Spatiotemporal fate map of neurogenin1 (Neurog1) lineages in the mouse central nervous system. J Comp Neurol. 2011;519:1355-70 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:3000
Zabouri N, Bouchard J, Casanova C. Cannabinoid receptor type 1 expression during postnatal development of the rat retina. J Comp Neurol. 2011;519:1258-80 pubmed 出版商
  • 免疫组化-冰冻切片; 斑马鱼; 1:500
Ramachandran R, Reifler A, Parent J, Goldman D. Conditional gene expression and lineage tracing of tuba1a expressing cells during zebrafish development and retina regeneration. J Comp Neurol. 2010;518:4196-212 pubmed 出版商
  • 免疫组化-冰冻切片; 斑马鱼; 1:1000
Grupp L, Wolburg H, Mack A. Astroglial structures in the zebrafish brain. J Comp Neurol. 2010;518:4277-87 pubmed 出版商
  • 免疫组化-石蜡切片; lepidosaurs; 1:500
  • 免疫印迹; lepidosaurs; 1:1000
Romero Alemán M, Monzon Mayor M, Santos E, Yanes C. Expression of neuronal markers, synaptic proteins, and glutamine synthetase in the control and regenerating lizard visual system. J Comp Neurol. 2010;518:4067-87 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:400
Phillips M, Otteson D, Sherry D. Progression of neuronal and synaptic remodeling in the rd10 mouse model of retinitis pigmentosa. J Comp Neurol. 2010;518:2071-89 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Gargini C, Terzibasi E, Mazzoni F, Strettoi E. Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a morphological and ERG study. J Comp Neurol. 2007;500:222-38 pubmed
Richier B, Vijandi C, Mackensen S, Salecker I. Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe. Nat Commun. 2017;8:317 pubmed 出版商
De Ita Pérez D, Díaz Muñoz M. Synchronization by Daytime Restricted Food Access Modulates the Presence and Subcellular Distribution of ?-Catenin and Its Phosphorylated Forms in the Rat Liver. Front Endocrinol (Lausanne). 2017;8:14 pubmed 出版商
Takahashi T, Nishida T, Baba H, Hatta H, Imura J, Sutoh M, et al. Histopathological characteristics of glutamine synthetase-positive hepatic tumor lesions in a mouse model of spontaneous metabolic syndrome (TSOD mouse). Mol Clin Oncol. 2016;5:267-270 pubmed
Sánchez Farías N, Candal E. Identification of Radial Glia Progenitors in the Developing and Adult Retina of Sharks. Front Neuroanat. 2016;10:65 pubmed 出版商
Bouvier D, Jones E, Quesseveur G, Davoli M, A Ferreira T, Quirion R, et al. High Resolution Dissection of Reactive Glial Nets in Alzheimer's Disease. Sci Rep. 2016;6:24544 pubmed 出版商
Byrne A, Roche S, Ruiz Lopez A, Jackson A, Cotter T. The synthetic progestin norgestrel acts to increase LIF levels in the rd10 mouse model of retinitis pigmentosa. Mol Vis. 2016;22:264-74 pubmed
Scholz R, Caramoy A, Bhuckory M, Rashid k, Chen M, Xu H, et al. Targeting translocator protein (18 kDa) (TSPO) dampens pro-inflammatory microglia reactivity in the retina and protects from degeneration. J Neuroinflammation. 2015;12:201 pubmed 出版商
Dray N, Bedu S, Vuillemin N, Alunni A, Coolen M, Krecsmarik M, et al. Large-scale live imaging of adult neural stem cells in their endogenous niche. Development. 2015;142:3592-600 pubmed 出版商
Greferath U, Anderson E, Jobling A, Vessey K, Martinez G, de Iongh R, et al. Inner retinal change in a novel rd1-FTL mouse model of retinal degeneration. Front Cell Neurosci. 2015;9:293 pubmed 出版商
Wang B, Zhao L, Fish M, Logan C, Nusse R. Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver. Nature. 2015;524:180-5 pubmed 出版商
Niu W, Zang T, Smith D, Vue T, Zou Y, Bachoo R, et al. SOX2 reprograms resident astrocytes into neural progenitors in the adult brain. Stem Cell Reports. 2015;4:780-94 pubmed 出版商
Yan R, He L, Zhan W, Wang S. Induction of ectopic retina-like tissue by transgenic expression of neurogenin. PLoS ONE. 2015;10:e0116171 pubmed 出版商
King J, Feist R, Mason J, Morris R, Guidry C. Evaluation of proliferating cell abundance and phenotypes in proliferative diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol. 2015;253:229-36 pubmed 出版商
Cécyre B, Monette M, Beudjekian L, Casanova C, Bouchard J. Localization of diacylglycerol lipase alpha and monoacylglycerol lipase during postnatal development of the rat retina. Front Neuroanat. 2014;8:150 pubmed 出版商
Greferath U, Vessey K, Jobling A, Mills S, Bui B, He Z, et al. The role of histamine in the retina: studies on the Hdc knockout mouse. PLoS ONE. 2014;9:e116025 pubmed 出版商
Inoue M, Takahashi Y, Fujii T, Kitagawa M, Fukusato T. Significance of downregulation of liver fatty acid-binding protein in hepatocellular carcinoma. World J Gastroenterol. 2014;20:17541-51 pubmed 出版商
Jiang R, Haustein M, Sofroniew M, Khakh B. Imaging intracellular Ca²⁺ signals in striatal astrocytes from adult mice using genetically-encoded calcium indicators. J Vis Exp. 2014;:e51972 pubmed 出版商
Bhatti F, Ball G, Hobbs R, Linens A, Munzar S, Akram R, et al. Pulmonary surfactant protein a is expressed in mouse retina by Müller cells and impacts neovascularization in oxygen-induced retinopathy. Invest Ophthalmol Vis Sci. 2014;56:232-42 pubmed 出版商
Soundararajan R, Won J, Stearns T, Charette J, Hicks W, Collin G, et al. Gene profiling of postnatal Mfrprd6 mutant eyes reveals differential accumulation of Prss56, visual cycle and phototransduction mRNAs. PLoS ONE. 2014;9:e110299 pubmed 出版商
Nascimento D, Castro Lopes J, Moreira Neto F. Satellite glial cells surrounding primary afferent neurons are activated and proliferate during monoarthritis in rats: is there a role for ATF3?. PLoS ONE. 2014;9:e108152 pubmed 出版商
Lindsey B, Di Donato S, Kaslin J, Tropepe V. Sensory-specific modulation of adult neurogenesis in sensory structures is associated with the type of stem cell present in the neurogenic niche of the zebrafish brain. Eur J Neurosci. 2014;40:3591-607 pubmed 出版商
Nault J, Calderaro J, Di Tommaso L, Balabaud C, Zafrani E, Bioulac Sage P, et al. Telomerase reverse transcriptase promoter mutation is an early somatic genetic alteration in the transformation of premalignant nodules in hepatocellular carcinoma on cirrhosis. Hepatology. 2014;60:1983-92 pubmed 出版商
Agarwal S, Fuentes Orrego J, Arnason T, Misdraji J, Jhaveri K, Harisinghani M, et al. Inflammatory hepatocellular adenomas can mimic focal nodular hyperplasia on gadoxetic acid-enhanced MRI. AJR Am J Roentgenol. 2014;203:W408-14 pubmed 出版商
Semba K, Namekata K, Guo X, Harada C, Harada T, Mitamura Y. Renin-angiotensin system regulates neurodegeneration in a mouse model of normal tension glaucoma. Cell Death Dis. 2014;5:e1333 pubmed 出版商
Nayagam D, Williams R, Allen P, Shivdasani M, Luu C, Salinas LaRosa C, et al. Chronic electrical stimulation with a suprachoroidal retinal prosthesis: a preclinical safety and efficacy study. PLoS ONE. 2014;9:e97182 pubmed 出版商
Zayas Santiago A, Agte S, Rivera Y, Benedikt J, Ulbricht E, Karl A, et al. Unidirectional photoreceptor-to-Müller glia coupling and unique K+ channel expression in Caiman retina. PLoS ONE. 2014;9:e97155 pubmed 出版商
Yamashita T, Kitao A, Matsui O, Hayashi T, Nio K, Kondo M, et al. Gd-EOB-DTPA-enhanced magnetic resonance imaging and alpha-fetoprotein predict prognosis of early-stage hepatocellular carcinoma. Hepatology. 2014;60:1674-85 pubmed 出版商
Shen W, Lee S, Araújo J, Chung S, Zhu L, Gillies M. Effect of glucocorticoids on neuronal and vascular pathology in a transgenic model of selective Müller cell ablation. Glia. 2014;62:1110-24 pubmed 出版商
Mostafeezur R, Shinoda M, Unno S, Zakir H, Takatsuji H, Takahashi K, et al. Involvement of astroglial glutamate-glutamine shuttle in modulation of the jaw-opening reflex following infraorbital nerve injury. Eur J Neurosci. 2014;39:2050-9 pubmed 出版商
Gu X, Reagan A, Yen A, Bhatti F, Cohen A, Elliott M. Spatial and temporal localization of caveolin-1 protein in the developing retina. Adv Exp Med Biol. 2014;801:15-21 pubmed 出版商
Caprara C, Britschgi C, Samardzija M, Grimm C. The erythropoietin receptor is not required for the development, function, and aging of rods and cells in the retinal periphery. Mol Vis. 2014;20:307-24 pubmed
Allen R, Sayeed I, Cale H, Morrison K, Boatright J, Pardue M, et al. Severity of middle cerebral artery occlusion determines retinal deficits in rats. Exp Neurol. 2014;254:206-15 pubmed 出版商
Raddant A, Russo A. Reactive oxygen species induce procalcitonin expression in trigeminal ganglia glia. Headache. 2014;54:472-84 pubmed 出版商
Sosunov A, Wu X, Tsankova N, Guilfoyle E, McKhann G, Goldman J. Phenotypic heterogeneity and plasticity of isocortical and hippocampal astrocytes in the human brain. J Neurosci. 2014;34:2285-98 pubmed 出版商
Krings G, Can B, Ferrell L. Aberrant centrizonal features in chronic hepatic venous outflow obstruction: centrilobular mimicry of portal-based disease. Am J Surg Pathol. 2014;38:205-14 pubmed 出版商
Vacca O, Darche M, Schaffer D, Flannery J, Sahel J, Rendon A, et al. AAV-mediated gene delivery in Dp71-null mouse model with compromised barriers. Glia. 2014;62:468-76 pubmed 出版商
Verginelli F, Perin A, Dali R, Fung K, Lo R, Longatti P, et al. Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth. Nat Commun. 2013;4:2956 pubmed 出版商
Rauscher F, Azmanis P, Körber N, Koch C, Hübel J, Vetterlein W, et al. Optical coherence tomography as a diagnostic tool for retinal pathologies in avian ophthalmology. Invest Ophthalmol Vis Sci. 2013;54:8259-69 pubmed 出版商
Bouskila J, Javadi P, Casanova C, Ptito M, Bouchard J. Rod photoreceptors express GPR55 in the adult vervet monkey retina. PLoS ONE. 2013;8:e81080 pubmed 出版商
Shen W, Zhu L, Lee S, Chung S, Gillies M. Involvement of NT3 and P75(NTR) in photoreceptor degeneration following selective Müller cell ablation. J Neuroinflammation. 2013;10:137 pubmed 出版商
Puschmann T, Zandén C, Lebkuechner I, Philippot C, de Pablo Y, Liu J, et al. HB-EGF affects astrocyte morphology, proliferation, differentiation, and the expression of intermediate filament proteins. J Neurochem. 2014;128:878-89 pubmed 出版商
Anlauf E, Derouiche A. Glutamine synthetase as an astrocytic marker: its cell type and vesicle localization. Front Endocrinol (Lausanne). 2013;4:144 pubmed 出版商
Donegan M, Kernisant M, Cua C, Jasmin L, Ohara P. Satellite glial cell proliferation in the trigeminal ganglia after chronic constriction injury of the infraorbital nerve. Glia. 2013;61:2000-8 pubmed 出版商
Kulijewicz Nawrot M, Sykova E, Chvatal A, Verkhratsky A, Rodriguez J. Astrocytes and glutamate homoeostasis in Alzheimer's disease: a decrease in glutamine synthetase, but not in glutamate transporter-1, in the prefrontal cortex. ASN Neuro. 2013;5:273-82 pubmed 出版商
Yeh C, Verkhratsky A, Terzieva S, Rodriguez J. Glutamine synthetase in astrocytes from entorhinal cortex of the triple transgenic animal model of Alzheimer's disease is not affected by pathological progression. Biogerontology. 2013;14:777-87 pubmed 出版商
Chung S, Shen W, Gillies M. Laser capture microdissection-directed profiling of glycolytic and mTOR pathways in areas of selectively ablated Müller cells in the murine retina. Invest Ophthalmol Vis Sci. 2013;54:6578-85 pubmed 出版商
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Tekmen Clark M, Gleason E. Nitric oxide production and the expression of two nitric oxide synthases in the avian retina. Vis Neurosci. 2013;30:91-103 pubmed 出版商
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产品信息
目录代码 :
MAB302
亚类别 :
神经科学
产品名称 :
抗谷氨酰胺合成抗体, 克隆GS-6
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P15104
宿主名称 :
小鼠
抗原 :
谷氨酰胺合成
克隆 :
GS-6
共轭标签 :
纯化
抗体亚型 :
IgG2a
产品描述 :
抗谷氨酰胺合成抗体, 克隆GS-6
交叉活性 :
人类;小鼠;大鼠;羊
背景 :
Glutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. It is found in astrocytes as an octamer of identical 45 kDa subunits. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. The level of expression of Glutamine Synthetase is increased during ischemia in vivo or hypoxia in culture.
免疫原 :
谷氨酰胺合成纯化来自羊大脑
特异性 :
Reacts strongly with a single band on Western blots of sheep brain and rat brain. Glutamine synthetase, an enzyme that catalyzes the amination of glutamic acid to form glutamine, is found in mammals as an octamer of eight identical 45 kDa subunits. Glutamine synthetase activity has been shown to be a useful marker of astrocytes and an important differentiation feature in retina. Glutamine synthetase is also considered to be a key enzyme in the recycling of the neurotransmitter glutamate.
包装尺寸 :
100微克
用途 :
酶联免疫吸附测定;免疫组化;免疫组化(石蜡);免疫印迹
储存 :
Maintain antibody at 2–8°C in undiluted aliquots for up to 12 months. Avoid repeated freeze-thaw cycles.
更多信息或购买 :
公司信息
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公司总部: 美国
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