This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
APP A4 Antibody, a.a. 66-81 of APP (NT), clone 22C11
目录 :
MAB348-100微升
规格 :
100微升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
22C11

同一抗体克隆可从以下厂商购到:
反应物种 :
人类
产品信息
目录代码 :
MAB348-100微升
亚类别 :
神经科学
产品名称 :
Anti-APP A4 Antibody, a.a. 66-81 of APP (NT), clone 22C11
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P05067
宿主名称 :
小鼠
抗原 :
淀粉样蛋白前体A4
克隆 :
22C11
共轭标签 :
腹水
抗体亚型 :
IgG1
产品描述 :
Anti-APP A4 Antibody, a.a. 66-81 of APP (NT), clone 22C11
交叉活性 :
Human;Mouse;Rat;Monkey;Pig;Fish
背景 :
Amyloid Precursor Protein (APP) is expressed in the brain, kidney, heart, and spleen of fetal tissues; it is induced during neuronal differentiation. The most-substantiated role for APP is in synaptic formation and repair; its expression is upregulated during neuronal differentiation and after neural injury. In adult brain, highest expression of APP is found in the frontal lobe of the cortex. Moderate expression is observed in the cerebellar cortex, the posterior perisylvian cortex-opercular gyri and the temporal associated cortex. Defects in APP are a cause of autosomal dominant Alzheimer's disease (AD). Deposits of amyloid protein in senile plaques near nerve processes are found in the brains of aged humans and in cases of Alzheimer's disease. The principle component of this extracellular amyloid is beta/A4, a 4 kDa peptide derived from the larger APP. The creation, transport and function of these proteins are currently under investigation.
别名 :
淀粉样蛋白前体
免疫原 :
Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein.
特异性 :
Reacts with pre-A4. The antibody recognizes a N-terminal epitope on the pre-A4 molecule
包装尺寸 :
100微升
用途 :
免疫荧光;免疫组化;免疫组化(石蜡);免疫印迹
储存 :
Stable for 1 year at -20ºC from date of receipt.
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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