This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
甘油醛3脱氢酶抗体, 克隆6C5
目录 :
MAB374
规格 :
200微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6C5

同一抗体克隆可从以下厂商购到:
反应物种 :
鼩鼱科, least shrew, African green monkey, zebra finch, 人类, 小鼠, 大鼠, , , 斑马鱼, , 非洲爪蛙, domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-冰冻切片
文章摘录数: 1277
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 1c
Lamaa A, Humbert J, Aguirrebengoa M, Cheng X, Nicolas E, Cote J, et al. Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 6d
Guo X, Kolpakov M, Hooshdaran B, Schappell W, Wang T, Eguchi S, et al. Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload. JACC Basic Transl Sci. 2020;5:69-83 pubmed 出版商
  • 免疫印迹; 大鼠; 图 6f
Sarker M, Lee J, Lee D, Chun K, Jun H. Attenuation of diabetic kidney injury in DPP4-deficient rats; role of GLP-1 on the suppression of AGE formation by inducing glyoxalase 1. Aging (Albany NY). 2020;12:593-610 pubmed 出版商
  • 免疫印迹; 小鼠; 1:300; 图 s1a
Even A, Morelli G, Broix L, Scaramuzzino C, Turchetto S, Gladwyn Ng I, et al. ATAT1-enriched vesicles promote microtubule acetylation via axonal transport. Sci Adv. 2019;5:eaax2705 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3c
Harde E, Nicholson L, Furones Cuadrado B, Bissen D, Wigge S, Urban S, et al. EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Wessel S, Mohni K, Luzwick J, Dungrawala H, Cortez D. Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators. Cell Rep. 2019;28:3497-3509.e4 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2a
Wolf Y, Bartok O, Patkar S, Eli G, Cohen S, Litchfield K, et al. UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma. Cell. 2019;179:219-235.e21 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1c
Shao Q, Esseltine J, Huang T, Novielli Kuntz N, Ching J, SAMPSON J, et al. Connexin43 is Dispensable for Early Stage Human Mesenchymal Stem Cell Adipogenic Differentiation But is Protective against Cell Senescence. Biomolecules. 2019;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 2g
Suh J, Romano D, Nitschke L, Herrick S, DiMarzio B, Dzhala V, et al. Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription. Cell. 2019;178:1159-1175.e17 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4g
Gal H, Lysenko M, Stroganov S, Vadai E, Youssef S, Tzadikevitch Geffen K, et al. Molecular pathways of senescence regulate placental structure and function. EMBO J. 2019;38:e100849 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1b
Wu S, Fatkhutdinov N, Rosin L, Luppino J, Iwasaki O, Tanizawa H, et al. ARID1A spatially partitions interphase chromosomes. Sci Adv. 2019;5:eaaw5294 pubmed 出版商
  • 免疫印迹; 人类; 图 s1a
Kucab J, Zou X, Morganella S, Joel M, Nanda A, Nagy E, et al. A Compendium of Mutational Signatures of Environmental Agents. Cell. 2019;177:821-836.e16 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 s2f
Montalbán Loro R, Lozano Ureña A, Ito M, Krueger C, Reik W, Ferguson Smith A, et al. TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn. Nat Commun. 2019;10:1726 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2b
Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, et al. Autophagy regulates lipid metabolism through selective turnover of NCoR1. Nat Commun. 2019;10:1567 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 2d
Gong B, Kiyotani K, Sakata S, Nagano S, Kumehara S, Baba S, et al. Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer. J Exp Med. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Georgouli M, Herraiz C, Crosas Molist E, Fanshawe B, Maiques O, Perdrix A, et al. Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell. 2019;176:757-774.e23 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000; 图 2a
Stojic A, Bojcevski J, Williams S, Bas Orth C, Nessler S, Linington C, et al. Preclinical stress originates in the rat optic nerve head during development of autoimmune optic neuritis. Glia. 2019;67:512-524 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Fukushima M, Dasgupta D, Mauer A, Kakazu E, Nakao K, Malhi H. StAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis. J Biol Chem. 2018;293:15277-15289 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 1c
Ziegler Waldkirch S, d Errico P, Sauer J, Erny D, Savanthrapadian S, Loreth D, et al. Seed-induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease. EMBO J. 2018;37:167-182 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Liu S, Cheng C. Akt Signaling Is Sustained by a CD44 Splice Isoform-Mediated Positive Feedback Loop. Cancer Res. 2017;77:3791-3801 pubmed 出版商
  • 免疫印迹; 人类; 1:50,000; 图 3c
Menges S, Minakaki G, Schaefer P, Meixner H, Prots I, Schlötzer Schrehardt U, et al. Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress. Sci Rep. 2017;7:42942 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 1
Herring A, Messana A, Bara A, Hazelbaker D, Eggan K, Barrett L. Generation of a TLE1 homozygous knockout human embryonic stem cell line using CRISPR-Cas9. Stem Cell Res. 2016;17:430-432 pubmed 出版商
  • 免疫印迹; 人类; 图 s3b
Someya A, Ikegami T, Sakamoto K, Nagaoka I. Glucosamine Downregulates the IL-1?-Induced Expression of Proinflammatory Cytokine Genes in Human Synovial MH7A Cells by O-GlcNAc Modification-Dependent and -Independent Mechanisms. PLoS ONE. 2016;11:e0165158 pubmed 出版商
  • 免疫印迹; 人类; 1:300; 图 s3
Anderson D, Markway B, Bond D, McCarthy H, Johnstone B. Responses to altered oxygen tension are distinct between human stem cells of high and low chondrogenic capacity. Stem Cell Res Ther. 2016;7:154 pubmed
  • 免疫印迹; 小鼠; 1:1000; 图 1d
Cortes D, Robledo Arratia Y, Hernández Martinez R, Escobedo Ávila I, Bargas J, Velasco I. Transgenic GDNF Positively Influences Proliferation, Differentiation, Maturation and Survival of Motor Neurons Produced from Mouse Embryonic Stem Cells. Front Cell Neurosci. 2016;10:217 pubmed 出版商
  • 免疫印迹; 人类; 1:100; 图 4
Bener G, J Félix A, Sánchez de Diego C, Pascual Fabregat I, Ciudad C, Noe V. Silencing of CD47 and SIRP? by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells. BMC Immunol. 2016;17:32 pubmed
  • 免疫印迹; 人类; 1:5000; 图 3
Shamblott M, O Driscoll M, Gomez D, McGuire D. Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas. Cell Commun Signal. 2016;14:23 pubmed
  • 免疫印迹; 人类; 图 5
Watanabe S, Simon V, Durham N, Kemp B, Machihara S, Kemal K, et al. The HIV-1 late domain-2 S40A polymorphism in antiretroviral (or ART)-exposed individuals influences protease inhibitor susceptibility. Retrovirology. 2016;13:64 pubmed 出版商
  • 免疫印迹; 小鼠; 图 9h
Krawczyk K, Ekman M, Rippe C, Grossi M, Nilsson B, Albinsson S, et al. Assessing the contribution of thrombospondin-4 induction and ATF6? activation to endoplasmic reticulum expansion and phenotypic modulation in bladder outlet obstruction. Sci Rep. 2016;6:32449 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
  • 免疫印迹; 人类; 1:1500; 图 3a
Padhan N, Nordling T, Sundstrom M, Akerud P, Birgisson H, Nygren P, et al. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer. BMC Cancer. 2016;16:683 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Kim M, Caplen N, Chakka S, Hernandez L, House C, Pongas G, et al. Identification of therapeutic targets applicable to clinical strategies in ovarian cancer. BMC Cancer. 2016;16:678 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 5g
Fujita K, Motoki K, Tagawa K, Chen X, Hama H, Nakajima K, et al. HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease. Sci Rep. 2016;6:31895 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Ruiz Palmero I, Ortiz Rodriguez A, Melcangi R, Caruso D, Garcia Segura L, Rune G, et al. Oestradiol synthesized by female neurons generates sex differences in neuritogenesis. Sci Rep. 2016;6:31891 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 6
Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, et al. Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nat Commun. 2016;7:12503 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6
Gygli P, Chang J, Gokozan H, Catacutan F, Schmidt T, Kaya B, et al. Cyclin A2 promotes DNA repair in the brain during both development and aging. Aging (Albany NY). 2016;8:1540-70 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 1
Manassero G, Guglielmotto M, Zamfir R, Borghi R, Colombo L, Salmona M, et al. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein. Aging Cell. 2016;15:914-23 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
  • 免疫印迹; 人类; 图 1
Sohn P, Tracy T, Son H, Zhou Y, Leite R, Miller B, et al. Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment. Mol Neurodegener. 2016;11:47 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Wang Y, Li Y, Hu G, Huang X, Rao H, Xiong X, et al. Nek2A phosphorylates and stabilizes SuFu: A new strategy of Gli2/Hedgehog signaling regulatory mechanism. Cell Signal. 2016;28:1304-13 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Hey F, Giblett S, Forrest S, Herbert C, Pritchard C. Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine. PLoS ONE. 2016;11:e0156877 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Martin G, Chung S, Landrock D, Landrock K, Huang H, Dangott L, et al. FABP-1 gene ablation impacts brain endocannabinoid system in male mice. J Neurochem. 2016;138:407-22 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Ding J, Nie M, Liu J, Hu X, Ma L, Deng Z, et al. Trbp Is Required for Differentiation of Myoblasts and Normal Regeneration of Skeletal Muscle. PLoS ONE. 2016;11:e0155349 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Meinders M, Hoogenboezem M, Scheenstra M, De Cuyper I, Papadopoulos P, Nemeth T, et al. Repercussion of Megakaryocyte-Specific Gata1 Loss on Megakaryopoiesis and the Hematopoietic Precursor Compartment. PLoS ONE. 2016;11:e0154342 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 1
Chen P, Hsiao J, Sirois C, Chamberlain S. RBFOX1 and RBFOX2 are dispensable in iPSCs and iPSC-derived neurons and do not contribute to neural-specific paternal UBE3A silencing. Sci Rep. 2016;6:25368 pubmed 出版商
  • 免疫印迹; 大鼠; 1:5000; 图 4
Mao Y, Tamura T, Yuki Y, Abe D, Tamada Y, Imoto S, et al. The hnRNP-Htt axis regulates necrotic cell death induced by transcriptional repression through impaired RNA splicing. Cell Death Dis. 2016;7:e2207 pubmed 出版商
  • 免疫印迹; 小鼠; 1:8000; 图 2
Sun M, Asghar S, Zhang H. The polarity protein Par3 regulates APP trafficking and processing through the endocytic adaptor protein Numb. Neurobiol Dis. 2016;93:1-11 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Valero T, Sturchler E, Jafferjee M, Rengo G, Magafa V, Cordopatis P, et al. Structure-activity relationship study of angiotensin II analogs in terms of β-arrestin-dependent signaling to aldosterone production. Pharmacol Res Perspect. 2016;4:e00226 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 4
Gómez López S, Martínez Silva A, Montiel T, Osorio Gómez D, Bermudez Rattoni F, Massieu L, et al. Neural ablation of the PARK10 candidate Plpp3 leads to dopaminergic transmission deficits without neurodegeneration. Sci Rep. 2016;6:24028 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Waguia Kontchou C, Tzivelekidis T, Gentle I, Hacker G. Infection of epithelial cells with Chlamydia trachomatis inhibits TNF-induced apoptosis at the level of receptor internalization while leaving non-apoptotic TNF-signalling intact. Cell Microbiol. 2016;18:1583-1595 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 4
Pijut S, Corbett D, Wang Y, Li J, Charnigo R, Graf G. Effect of peripheral circadian dysfunction on metabolic disease in response to a diabetogenic diet. Am J Physiol Endocrinol Metab. 2016;310:E900-11 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Yan X, Nykänen N, Brunello C, Haapasalo A, Hiltunen M, Uronen R, et al. FRMD4A-cytohesin signaling modulates the cellular release of tau. J Cell Sci. 2016;129:2003-15 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Massengill M, Ashraf H, Chowdhury R, Chrzanowski S, Kar J, Warren S, et al. Acute heart failure with cardiomyocyte atrophy induced in adult mice by ablation of cardiac myosin light chain kinase. Cardiovasc Res. 2016;111:34-43 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Prathipati P, Metreveli N, Nandi S, Tyagi S, Mishra P. Ablation of Matrix Metalloproteinase-9 Prevents Cardiomyocytes Contractile Dysfunction in Diabetics. Front Physiol. 2016;7:93 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2
Antony A, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, et al. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016;7:10955 pubmed 出版商
  • 免疫印迹; 小鼠; 1:30,000; 图 1
Johanns M, Lai Y, Hsu M, Jacobs R, Vertommen D, Van Sande J, et al. AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B. Nat Commun. 2016;7:10856 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 表 2
Carbognin E, Betto R, Soriano M, Smith A, Martello G. Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency. EMBO J. 2016;35:618-34 pubmed 出版商
  • 免疫印迹; 人类
Hoa L, Kulaberoglu Y, Gundogdu R, Cook D, Mavis M, Gomez M, et al. The characterisation of LATS2 kinase regulation in Hippo-YAP signalling. Cell Signal. 2016;28:488-497 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1500; 图 2
Puyang Z, Feng L, Chen H, Liang P, Troy J, Liu X. Retinal Ganglion Cell Loss is Delayed Following Optic Nerve Crush in NLRP3 Knockout Mice. Sci Rep. 2016;6:20998 pubmed 出版商
  • 免疫印迹; 人类; 1:25,000; 图 2
Kim N, Kim M, Sung P, Bae Y, Shin E, Yoo J. Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Nat Commun. 2016;7:10631 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Tanahashi H, Tian Q, Hara Y, Sakagami H, Endo S, Suzuki T. Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance. Sci Rep. 2016;6:20241 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 1
Sharma A, Lyashchenko A, Lu L, Nasrabady S, Elmaleh M, Mendelsohn M, et al. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function. Nat Commun. 2016;7:10465 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 1
Theodosiou M, Widmaier M, Böttcher R, Rognoni E, Veelders M, Bharadwaj M, et al. Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin. elife. 2016;5:e10130 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Abbey M, Hakim C, Anand R, Lafera J, Schambach A, Kispert A, et al. GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis. Sci Rep. 2016;6:20007 pubmed 出版商
  • 免疫印迹; 小鼠; 图 9
Park W, Kim S, Kim Y, Park J. Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription. Int J Mol Med. 2016;37:613-22 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
Gingras J, Gawor M, Bernadzki K, Grady R, Hallock P, Glass D, et al. Α-Dystrobrevin-1 recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction. J Cell Sci. 2016;129:898-911 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 5
Priglinger C, Obermann J, Szober C, Merl Pham J, Ohmayer U, Behler J, et al. Epithelial-to-Mesenchymal Transition of RPE Cells In Vitro Confers Increased β1,6-N-Glycosylation and Increased Susceptibility to Galectin-3 Binding. PLoS ONE. 2016;11:e0146887 pubmed 出版商
  • 免疫印迹; 小鼠; 1:25,000; 图 s4
Kucab J, Zwart E, van Steeg H, Luijten M, Schmeiser H, Phillips D, et al. TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts. DNA Repair (Amst). 2016;39:21-33 pubmed 出版商
  • 免疫印迹; 小鼠; 图 st1
Wang C, Che L, Hu J, Zhang S, Jiang L, Latte G, et al. Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade. Liver Int. 2016;36:1176-86 pubmed 出版商
  • 免疫印迹; 小鼠; 1:50,000
Parvatiyar M, Marshall J, Nguyen R, Jordan M, Richardson V, Roos K, et al. Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy-Associated Cardiomyopathy. J Am Heart Assoc. 2015;4: pubmed 出版商
  • 免疫印迹; 小鼠; 1:2500; 图 5
Xu J, El Refaey M, Xu L, Zhao L, Gao Y, Floyd K, et al. Genetic disruption of Ano5 in mice does not recapitulate human ANO5-deficient muscular dystrophy. Skelet Muscle. 2015;5:43 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 7
Gali Ramamoorthy T, Laverny G, Schlagowski A, Zoll J, Messaddeq N, Bornert J, et al. The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles. Nat Commun. 2015;6:10210 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 2
Ohashi A, Ohori M, Iwai K, Nambu T, Miyamoto M, Kawamoto T, et al. A Novel Time-Dependent CENP-E Inhibitor with Potent Antitumor Activity. PLoS ONE. 2015;10:e0144675 pubmed 出版商
  • 免疫印迹; 小鼠
Isbel L, Srivastava R, Oey H, Spurling A, Daxinger L, Puthalakath H, et al. Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome. PLoS Genet. 2015;11:e1005693 pubmed 出版商
  • 免疫印迹; 斑马鱼; 图 2
Furlan S, Mosole S, Murgia M, Nagaraj N, Argenton F, Volpe P, et al. Calsequestrins in skeletal and cardiac muscle from adult Danio rerio. J Muscle Res Cell Motil. 2016;37:27-39 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Chrisam M, Pirozzi M, Castagnaro S, Blaauw B, Polishchuck R, Cecconi F, et al. Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice. Autophagy. 2015;11:2142-52 pubmed 出版商
  • 免疫印迹; 小鼠; 1:20,000; 图 4a
Abshagen K, Senne M, Genz B, Thomas M, Vollmar B. Differential Effects of Axin2 Deficiency on the Fibrogenic and Regenerative Response in Livers of Bile Duct-Ligated Mice. Eur Surg Res. 2015;55:328-340 pubmed
  • 免疫印迹; 人类; 图 s10
Dale T, Clarke P, Esdar C, Waalboer D, Adeniji Popoola O, Ortiz Ruiz M, et al. A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease. Nat Chem Biol. 2015;11:973-980 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 3
Hruska M, Henderson N, Xia N, Le Marchand S, Dalva M. Anchoring and synaptic stability of PSD-95 is driven by ephrin-B3. Nat Neurosci. 2015;18:1594-605 pubmed 出版商
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Kizuka Y, Nakano M, Kitazume S, Saito T, Saido T, Taniguchi N. Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions. Biochem J. 2016;473:21-30 pubmed 出版商
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Yao X, Carlson D, Sun Y, Ma L, Wolf S, Minei J, et al. Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model. PLoS ONE. 2015;10:e0139416 pubmed 出版商
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Parsi S, Smith P, Goupil C, Dorval V, Hébert S. Preclinical Evaluation of miR-15/107 Family Members as Multifactorial Drug Targets for Alzheimer's Disease. Mol Ther Nucleic Acids. 2015;4:e256 pubmed 出版商
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Sirohi K, Kumari A, Radha V, Swarup G. A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin. PLoS ONE. 2015;10:e0138289 pubmed 出版商
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Kelly J, Shao Q, Jagger D, Laird D. Cx30 exhibits unique characteristics including a long half-life when assembled into gap junctions. J Cell Sci. 2015;128:3947-60 pubmed 出版商
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Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K. Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes. PLoS ONE. 2015;10:e0136952 pubmed 出版商
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Lin H, Ha K, Lu G, Fang X, Cheng R, Zuo Q, et al. Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair. Mol Cell Biol. 2015;35:3657-68 pubmed 出版商
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Umansky K, Gruenbaum Cohen Y, Tsoory M, Feldmesser E, Goldenberg D, Brenner O, et al. Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle Regeneration. PLoS Genet. 2015;11:e1005457 pubmed 出版商
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Pasek J, Wang X, Colbran R. Differential CaMKII regulation by voltage-gated calcium channels in the striatum. Mol Cell Neurosci. 2015;68:234-43 pubmed 出版商
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Hagl S, Berressem D, Grewal R, Sus N, Frank J, Eckert G. Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice. Nutr Neurosci. 2016;19:1-10 pubmed 出版商
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Ma Q, Hu Q, Xu R, Zhen X, Wang G. Protease Omi facilitates neurite outgrowth in mouse neuroblastoma N2a cells by cleaving transcription factor E2F1. Acta Pharmacol Sin. 2015;36:966-75 pubmed 出版商
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Kawalec M, BoratyÅ„ska JasiÅ„ska A, BerÄ™sewicz M, Dymkowska D, ZabÅ‚ocki K, ZabÅ‚ocka B. Mitofusin 2 Deficiency Affects Energy Metabolism and Mitochondrial Biogenesis in MEF Cells. PLoS ONE. 2015;10:e0134162 pubmed 出版商
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Ragan C, Harding K, Lonstein J. Associations among within-litter differences in early mothering received and later emotional behaviors, mothering, and cortical tryptophan hydroxylase-2 expression in female laboratory rats. Horm Behav. 2016;77:62-71 pubmed 出版商
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Thomas A, Eijgelaar W, Daemen M, Newby A. Foam Cell Formation In Vivo Converts Macrophages to a Pro-Fibrotic Phenotype. PLoS ONE. 2015;10:e0128163 pubmed 出版商
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Santosa D, Castoldi M, Paluschinski M, Sommerfeld A, Häussinger D. Hyperosmotic stress activates the expression of members of the miR-15/107 family and induces downregulation of anti-apoptotic genes in rat liver. Sci Rep. 2015;5:12292 pubmed 出版商
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Perera R, Stoykova S, Nicolay B, Ross K, Fitamant J, Boukhali M, et al. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature. 2015;524:361-5 pubmed 出版商
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Beckman D, Santos L, Americo T, Ledo J, de Mello F, Linden R. Prion Protein Modulates Monoaminergic Systems and Depressive-like Behavior in Mice. J Biol Chem. 2015;290:20488-98 pubmed 出版商
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Ohashi A, Ohori M, Iwai K, Nakayama Y, Nambu T, Morishita D, et al. Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells. Nat Commun. 2015;6:7668 pubmed 出版商
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Duan H, Zhang Y, Zhang X, Xu H, Shu J, Xu S. Antinociceptive roles of galanin receptor 1 in nucleus accumbens of rats in a model of neuropathic pain. J Neurosci Res. 2015;93:1542-51 pubmed 出版商
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Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed
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Nishioka M, Venkatesan N, Dessalle K, Mogas A, Kyoh S, Lin T, et al. Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients. Respir Res. 2015;16:72 pubmed 出版商
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Dille S, Kleinschnitz E, Kontchou C, Nölke T, Häcker G. In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport. Infect Immun. 2015;83:3268-80 pubmed 出版商
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Ding J, Chen J, Wang Y, Kataoka M, Ma L, Zhou P, et al. Trbp regulates heart function through microRNA-mediated Sox6 repression. Nat Genet. 2015;47:776-83 pubmed 出版商
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Chuprin A, Avin A, Goldfarb Y, Herzig Y, Levi B, Jacob A, et al. The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance. Nat Immunol. 2015;16:737-45 pubmed 出版商
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Petrov D, Pedrós I, Artiach G, Sureda F, Barroso E, Pallas M, et al. High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents. Biochim Biophys Acta. 2015;1852:1687-99 pubmed 出版商
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Krais A, Speksnijder E, Melis J, Indra R, Moserova M, Godschalk R, et al. The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice. Arch Toxicol. 2016;90:839-51 pubmed 出版商
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Bozickovic O, Hoang T, Fenne I, Helland T, Skartveit L, Ouchida M, et al. Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells. Biochim Biophys Acta. 2015;1853:2383-91 pubmed 出版商
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De Zio D, Molinari F, Rizza S, Gatta L, Ciotti M, Salvatore A, et al. Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth. Cell Mol Life Sci. 2015;72:4173-91 pubmed 出版商
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Heinen A, Beyer F, Tzekova N, Hartung H, Küry P. Fingolimod induces the transition to a nerve regeneration promoting Schwann cell phenotype. Exp Neurol. 2015;271:25-35 pubmed 出版商
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Bernard L, Zhang H. MARK/Par1 Kinase Is Activated Downstream of NMDA Receptors through a PKA-Dependent Mechanism. PLoS ONE. 2015;10:e0124816 pubmed 出版商
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Chimura T, Launey T, Yoshida N. Calpain-Mediated Degradation of Drebrin by Excitotoxicity In vitro and In vivo. PLoS ONE. 2015;10:e0125119 pubmed 出版商
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Chung J, Bauer D, Ghamari A, Nizzi C, Deck K, Kingsley P, et al. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Sci Signal. 2015;8:ra34 pubmed 出版商
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Fei F, Joo E, Tarighat S, Schiffer I, Paz H, Fabbri M, et al. B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3. Oncotarget. 2015;6:11378-94 pubmed
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Chen M, Gan X, Deng L, Hotta H. The NS5A protein of hepatitis C virus transcriptionally upregulates the AGR3 gene expression. Kobe J Med Sci. 2015;61:E27-35 pubmed
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Gillory L, Stewart J, Megison M, Waters A, Beierle E. Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival. J Surg Res. 2015;196:339-49 pubmed 出版商
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Lavoz C, Alique M, Rodrígues Díez R, Pato J, Keri G, Mezzano S, et al. Gremlin regulates renal inflammation via the vascular endothelial growth factor receptor 2 pathway. J Pathol. 2015;236:407-20 pubmed 出版商
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Nakamura K, Nakabayashi K, Htet Aung K, Aizawa K, Hori N, Yamauchi J, et al. DNA methyltransferase inhibitor zebularine induces human cholangiocarcinoma cell death through alteration of DNA methylation status. PLoS ONE. 2015;10:e0120545 pubmed 出版商
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Ueda K, Yoshimura K, Yamashita O, Harada T, Morikage N, Hamano K. Possible dual role of decorin in abdominal aortic aneurysm. PLoS ONE. 2015;10:e0120689 pubmed 出版商
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Kim S, Wen W, Prowse P, Hamilton D. Regulation of matrix remodelling phenotype in gingival fibroblasts by substratum topography. J Cell Mol Med. 2015;19:1183-96 pubmed 出版商
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Lim J, Lachenmayer M, Wu S, Liu W, Kundu M, Wang R, et al. Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates. PLoS Genet. 2015;11:e1004987 pubmed 出版商
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van de Ven R, Tenhagen M, Meuleman W, van Riel J, Schackmann R, Derksen P. Nuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expression. Dis Model Mech. 2015;8:373-84 pubmed 出版商
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Heston J, White S. Behavior-linked FoxP2 regulation enables zebra finch vocal learning. J Neurosci. 2015;35:2885-94 pubmed 出版商
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Bertaux Skeirik N, Feng R, Schumacher M, Li J, Mahé M, Engevik A, et al. CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation. PLoS Pathog. 2015;11:e1004663 pubmed 出版商
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Stickles X, Marchion D, Bicaku E, Al Sawah E, Abbasi F, Xiong Y, et al. BAD-mediated apoptotic pathway is associated with human cancer development. Int J Mol Med. 2015;35:1081-7 pubmed 出版商
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Lewinska A, Wnuk M, Grabowska W, Zabek T, Semik E, Sikora E, et al. Curcumin induces oxidation-dependent cell cycle arrest mediated by SIRT7 inhibition of rDNA transcription in human aortic smooth muscle cells. Toxicol Lett. 2015;233:227-38 pubmed 出版商
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Jiang X, Ma T, Zhang Y, Zhang H, Yin S, Zheng W, et al. Specific deletion of Cdh2 in Sertoli cells leads to altered meiotic progression and subfertility of mice. Biol Reprod. 2015;92:79 pubmed 出版商
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Lee E, Kim S, Cho K. Reconstituted High-Density Lipoprotein Containing Human Growth Hormone-1 Shows Potent Tissue Regeneration Activity with Enhancement of Anti-Oxidant and Anti-Atherosclerotic Activities. Rejuvenation Res. 2015;18:245-56 pubmed 出版商
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Han X, Chen M, Hong T, Zhu L, He D, Feng J, et al. Lentivirus-mediated RNAi knockdown of the gap junction protein, Cx43, attenuates the development of vascular restenosis following balloon injury. Int J Mol Med. 2015;35:885-92 pubmed 出版商
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Singh K, Lovren F, Pan Y, Quan A, Ramadan A, Matkar P, et al. The essential autophagy gene ATG7 modulates organ fibrosis via regulation of endothelial-to-mesenchymal transition. J Biol Chem. 2015;290:2547-59 pubmed 出版商
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Ito H, Fujita K, Tagawa K, Chen X, Homma H, Sasabe T, et al. HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice. EMBO Mol Med. 2015;7:78-101 pubmed 出版商
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Bang B, Kim S, Yagita H, Croft M, Kang Y. Inhibition of 4-1BBL-regulated TLR response in macrophages ameliorates endotoxin-induced sepsis in mice. Eur J Immunol. 2015;45:886-92 pubmed 出版商
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Shen W, Li H, Chen G, Chern Y, Tu P. Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism. Autophagy. 2015;11:685-700 pubmed 出版商
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Wallingford M, Filkins R, Adams D, Walentuk M, Salicioni A, Visconti P, et al. Identification of a novel isoform of the leukemia-associated MLLT1 (ENL/LTG19) protein. Gene Expr Patterns. 2015;17:11-5 pubmed 出版商
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Langone F, Cannata S, Fuoco C, Lettieri Barbato D, Testa S, Nardozza A, et al. Metformin protects skeletal muscle from cardiotoxin induced degeneration. PLoS ONE. 2014;9:e114018 pubmed 出版商
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Liu Y, Atkinson R, Fernandez Martos C, Kirkcaldie M, Cui H, Vickers J, et al. Changes in TDP-43 expression in development, aging, and in the neurofilament light protein knockout mouse. Neurobiol Aging. 2015;36:1151-9 pubmed 出版商
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Fahl S, Harris B, Coffey F, Wiest D. Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint. J Immunol. 2015;194:200-9 pubmed
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Holloway A, Simmonds M, Azad A, Fox J, Storey A. Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase. Int J Cancer. 2015;136:2831-43 pubmed 出版商
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Jiang X, Zhang H, Yin S, Zhang Y, Yang W, Zheng W, et al. Specific deficiency of Plzf paralog, Zbtb20, in Sertoli cells does not affect spermatogenesis and fertility in mice. Sci Rep. 2014;4:7062 pubmed 出版商
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Stukas S, Robert J, Lee M, Kulic I, Carr M, Tourigny K, et al. Intravenously injected human apolipoprotein A-I rapidly enters the central nervous system via the choroid plexus. J Am Heart Assoc. 2014;3:e001156 pubmed 出版商
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Englert N, Luo G, Goldstein J, Surapureddi S. Epigenetic modification of histone 3 lysine 27: mediator subunit MED25 is required for the dissociation of polycomb repressive complex 2 from the promoter of cytochrome P450 2C9. J Biol Chem. 2015;290:2264-78 pubmed 出版商
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Chiang D, Kongchan N, Beavers D, Alsina K, Voigt N, Neilson J, et al. Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release. Circ Arrhythm Electrophysiol. 2014;7:1214-22 pubmed 出版商
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Pettinato G, Vanden Berg Foels W, Zhang N, Wen X. ROCK inhibitor is not required for embryoid body formation from singularized human embryonic stem cells. PLoS ONE. 2014;9:e100742 pubmed 出版商
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Matsuo R, Morihara H, Mohri T, Murasawa S, Takewaki K, Nakayama H, et al. The inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes. PLoS ONE. 2014;9:e111097 pubmed 出版商
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Miyamoto Y, Mauer A, Kumar S, Mott J, Malhi H. Mmu-miR-615-3p regulates lipoapoptosis by inhibiting C/EBP homologous protein. PLoS ONE. 2014;9:e109637 pubmed 出版商
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Orchard Webb D, Lee T, Cook G, Blair G. CUB domain containing protein 1 (CDCP1) modulates adhesion and motility in colon cancer cells. BMC Cancer. 2014;14:754 pubmed 出版商
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Martin G, Atshaves B, Landrock K, Landrock D, Storey S, Howles P, et al. Ablating L-FABP in SCP-2/SCP-x null mice impairs bile acid metabolism and biliary HDL-cholesterol secretion. Am J Physiol Gastrointest Liver Physiol. 2014;307:G1130-43 pubmed 出版商
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Kannike K, Sepp M, Zuccato C, Cattaneo E, Timmusk T. Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop. J Biol Chem. 2014;289:32845-57 pubmed 出版商
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Huang S, Lee C, Wang H, Chang Y, Lin C, Chen C, et al. 6-Dehydrogingerdione restrains lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages. J Agric Food Chem. 2014;62:9171-9 pubmed 出版商
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Radonjić N, Memi F, Ortega J, Glidden N, Zhan H, Zecevic N. The Role of Sonic Hedgehog in the Specification of Human Cortical Progenitors In Vitro. Cereb Cortex. 2016;26:131-43 pubmed 出版商
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Zhong W, Hutchinson T, Chebolu S, Darmani N. Serotonin 5-HT3 receptor-mediated vomiting occurs via the activation of Ca2+/CaMKII-dependent ERK1/2 signaling in the least shrew (Cryptotis parva). PLoS ONE. 2014;9:e104718 pubmed 出版商
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Xu R, Hu Q, Ma Q, Liu C, Wang G. The protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathway. Cell Death Dis. 2014;5:e1373 pubmed 出版商
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Balaz M, Ukropcova B, Kurdiova T, Gajdosechova L, Vlcek M, Janakova Z, et al. Adipokine zinc-?2-glycoprotein regulated by growth hormone and linked to insulin sensitivity. Obesity (Silver Spring). 2015;23:322-8 pubmed 出版商
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Matsuda M, Suzuki R, Kataoka C, Watashi K, Aizaki H, Kato N, et al. Alternative endocytosis pathway for productive entry of hepatitis C virus. J Gen Virol. 2014;95:2658-67 pubmed 出版商
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Zhang H, Petit G, Gaughwin P, Hansen C, Ranganathan S, Zuo X, et al. NGF rescues hippocampal cholinergic neuronal markers, restores neurogenesis, and improves the spatial working memory in a mouse model of Huntington's Disease. J Huntingtons Dis. 2013;2:69-82 pubmed 出版商
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产品信息
目录代码 :
MAB374
亚类别 :
代谢
产品名称 :
抗甘油醛3脱氢酶抗体, 克隆6C5
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P04406
宿主名称 :
小鼠
抗原 :
甘油醛3脱氢酶
克隆 :
6C5
共轭标签 :
纯化
抗体亚型 :
IgG1
产品描述 :
抗甘油醛3脱氢酶抗体, 克隆6C5
交叉活性 :
狗;人类;小鼠;大鼠;兔;鱼类;猫;猪
背景 :
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is an ubiquitous glycolytic enzyme present in reasonably high levels in almost all tissues. As a 'house-keeping' enzyme, it catalyzes the synthesis of 1,3-biphosphoglycerate, a "high energy" intermediate used for the synthesis of ATP. Besides its cytoplasmic action in metabolism it is also involved in the initial stages of apoptosis or oxidative stress response where GAPDH is translocated to the nucleus. Such actions may reflect the role of GAPDH in DNA repair or as one nuclear carrier for apoptotic molecules. GAPDH has also been found to bind specifically to proteins implicated in the pathogenesis of a variety of neurodegenerative disorders including the beta-amyloid precursor protein and the huntingtin protein where decreased function of GAPDH is associated with Alzheimer's and Huntington's disease fibroblasts. GAPDH has also been identified as a potential target for nitric oxide (NO)-mediated cellular toxicity. The complete and functional enzyme is a tetramer with each of four identical subunits occupying the vertex of a tetrahedron. Binding domains also include one principally interacting with NAD+ and another interacting with glyceraldehyde 3-phosphate (GAP).
别名 :
GAPDH;G3PDH;GAPD;OK/SW-cl.12;MGC88685;G3PD;EC 1.2.1.12
免疫原 :
甘油醛3脱氢酶来自兔肌肉
特异性 :
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from skeletal muscle. Antibody also recognizes cardiac GAPDH. GAPDH enzyme is detected in many non-muscle cells lines including HeLa, HCT-116 cells, U937 and THP-1 cells among others.
包装尺寸 :
200微克
用途 :
酶联免疫吸附测定;免疫沉淀;免疫细胞化学;免疫荧光;免疫组化;免疫印迹
储存 :
Maintain at 2-8ºC in undiluted aliquots for up to 6 months after date of receipt.
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

Hundreds of New Antibodies in the areas of:
  • • Cancer
  • • Nuclear Signaling
  • • Apoptosis
  • • Cardiovascular Disease
  • • Developmental Biology
  • • Metabolic Disease
  • • Neurodegenerative Disease
  • • Cell Biology
View all the new antibodies at www.emdmillipore.com.