产品简要
公司名称 :
默克密理博中国
其他品牌 :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
产品类型 :
抗体
产品名称 :
ZO-1抗体, 克隆R40.76
目录 :
MABT11
规格 :
100微克
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
R40.76
反应物种 :
人类, 小鼠, 犬, 鸡
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
默克密理博中国 产品网页
文章摘录数: 18
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 犬; 1:2000; 图 2f
Wu Q, Li G, Wen C, Zeng T, Fan Y, Liu C, et al. Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis. Sci Adv. 2020;6:eaay9819 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 5b
Cain S, Mularczyk E, Singh M, Massam Wu T, Kielty C. ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions. Sci Rep. 2016;6:35956 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 4
Harney A, Arwert E, Entenberg D, Wang Y, Guo P, Qian B, et al. Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA. Cancer Discov. 2015;5:932-43 pubmed 出版商
  • 免疫组化-冰冻切片; 鸡; 图 5
Chaves A, Vergara Alert J, Busquets N, Valle R, Rivas R, Ramis A, et al. Neuroinvasion of the highly pathogenic influenza virus H7N1 is caused by disruption of the blood brain barrier in an avian model. PLoS ONE. 2014;9:e115138 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Godde N, Sheridan J, Smith L, Pearson H, Britt K, Galea R, et al. Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland. PLoS Genet. 2014;10:e1004323 pubmed 出版商
  • 免疫组化; 小鼠
Kaenel P, Hahnewald S, Wotzkow C, Strange R, Andres A. Overexpression of EphB4 in the mammary epithelium shifts the differentiation pathway of progenitor cells and promotes branching activity and vascularization. Dev Growth Differ. 2014;56:255-75 pubmed 出版商
  • 免疫细胞化学; 人类
Tucker B, Mullins R, Streb L, Anfinson K, Eyestone M, Kaalberg E, et al. Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa. elife. 2013;2:e00824 pubmed 出版商
Kady N, Liu X, Lydic T, Syed M, Navitskaya S, Wang Q, et al. ELOVL4-Mediated Production of Very Long-Chain Ceramides Stabilizes Tight Junctions and Prevents Diabetes-Induced Retinal Vascular Permeability. Diabetes. 2018;67:769-781 pubmed 出版商
Ramos C, Lin C, Liu X, Antonetti D. The EPAC-Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability. J Biol Chem. 2018;293:717-730 pubmed 出版商
Lázaro Diéguez F, Müsch A. Cell-cell adhesion accounts for the different orientation of columnar and hepatocytic cell divisions. J Cell Biol. 2017;216:3847-3859 pubmed 出版商
Gao L, Yang Z, Hiremath C, Zimmerman S, Long B, BRAKEMAN P, et al. Afadin orients cell division to position the tubule lumen in developing renal tubules. Development. 2017;144:3511-3520 pubmed 出版商
Elfers K, Marr I, Wilkens M, Breves G, Langeheine M, Brehm R, et al. Expression of Tight Junction Proteins and Cadherin 17 in the Small Intestine of Young Goats Offered a Reduced N and/or Ca Diet. PLoS ONE. 2016;11:e0154311 pubmed 出版商
Songstad A, Wiley L, Duong K, Kaalberg E, Flamme Wiese M, Cranston C, et al. Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci. 2015;56:8258-67 pubmed 出版商
Valcourt U, Carthy J, Okita Y, Alcaraz L, Kato M, Thuault S, et al. Analysis of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor β. Methods Mol Biol. 2016;1344:147-81 pubmed 出版商
Coulson Thomas V, Caterson B, Kao W. Transplantation of human umbilical mesenchymal stem cells cures the corneal defects of mucopolysaccharidosis VII mice. Stem Cells. 2013;31:2116-26 pubmed 出版商
Hoopes S, Willcockson H, Caron K. Characteristics of multi-organ lymphangiectasia resulting from temporal deletion of calcitonin receptor-like receptor in adult mice. PLoS ONE. 2012;7:e45261 pubmed 出版商
Mikelsaar A, Sünter A, Mikelsaar R, Toomik P, Kõiveer A, Mikelsaar I, et al. Epitope of titin A-band-specific monoclonal antibody Tit1 5 H1.1 is highly conserved in several Fn3 domains of the titin molecule. Centriole staining in human, mouse and zebrafish cells. Cell Div. 2012;7:21 pubmed 出版商
Kaenel P, Antonijevic M, Richter S, Küchler S, Sutter N, Wotzkow C, et al. Deregulated ephrin-B2 signaling in mammary epithelial cells alters the stem cell compartment and interferes with the epithelial differentiation pathway. Int J Oncol. 2012;40:357-69 pubmed 出版商
产品信息
目录代码 :
MABT11
亚类别 :
Cell Structure
产品名称 :
抗ZO-1抗体, 克隆R40.76
产品类型 :
抗体
克隆性 :
单克隆抗体
基因编号 :
P39447
宿主名称 :
大鼠
抗原 :
ZO-1
克隆 :
R40.76
共轭标签 :
纯化
抗体亚型 :
IgG2aκ
产品描述 :
抗ZO-1抗体, 克隆R40.76
交叉活性 :
小鼠;大鼠
背景 :
Tight junctions are complexes of proteins that create intercellular boundaries between the plasma membrane domains of epithelial and endothelial cells. Many of the tight junction-associated proteins are members of the membrane associated guanylate kinase (MAGUK) family and include occludin and zona occludin family members ZO-1, ZO-2 and ZO-3. These proteins are thought to have both structural and signaling roles, and are characteristically defined by three protein-protein interaction modules: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue.
别名 :
tight junction protein 1;zonula occludens 1 protein;Zona occludens protein 1;Zonula occludens protein 1;zona occludens 1
免疫原 :
Purified protein corresponding to mouse ZO-1.
特异性 :
抗体识别ZO-1
包装尺寸 :
100微克
用途 :
免疫印迹;免疫沉淀;免疫组化
储存 :
收到之日起在2-8℃稳定1年
更多信息或购买 :
默克密理博中国 产品网页
公司信息
默克密理博中国
上海市浦东张江高科技园区晨晖路88号2号楼2楼
asiatechserv@millipore.com
http://www.millipore.com/china/wwcn/cnhome
400-889-1988
公司总部: 美国
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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