ELISA/assay

ICA (Islet Cell Antibody) screen ELISA

ICA31-K01

1 x 96 well

735.00美元

ICA (Islet Cell Antibody) screen ELISA

Type 1 diabetes, also known as insulin-dependent diabetes mellitus (IDDM), results from a chronic autoimmune process which destructs the insulin-secreting pancreatic beta cells. This is caused by simultaneous action of specific auto-reactive CD4+ and CD8+ T lymphocytes. Even before the onset of type 1 diabetes autoantibodies against different Antigenss of the islet cells can be detected in the serum of those patients. This process may take years to complete and may occur at any time at all ages.

The ICA Screen ELISA Assay Kit system uses the ability of IC autoantibodies to act di-valently, that is, to form a bridge between autoAntigenss (highly purified material from primate source) coated onto the plate and liquid phase autoAntigens-Biotin. In the first step IC autoantibodies from the sample bind to autoAntigenss coated on the microtiter plate. In a second step IC-autoAntigens-Biotin binds to this complex which correlates with the amount of IC autoantibodies in patient’s serum. Unbound IC-autoAntigens-Biotin is removed by washing.

酶联免疫吸附测定

检测试剂盒

内分泌学

1 x 96 well

ICA

ICA, Islet Cell Antibody, Antibodies

Cut Off

Cut Off

50微升

血清

overnight

人类

RUO

wet

2-8C

735.00美元