产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
ELISA/assay
产品名称 :
PGE2酶联免疫吸附试剂盒
目录 :
ADI-900-001
规格 :
96 wells
更多信息或购买 :
文章摘录数: 23
参考文献 |
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Shang J, Cheng Q, Yang W, Zhang M, Cui Y, Wang Y. Possible roles of COX-1 in learning and memory impairment induced by traumatic brain injury in mice. Braz J Med Biol Res. 2014;47:1050-6 pubmed
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Kim H, Ju M, Ha S, Lee H, Lee H, Kim S, et al. Acacetin protects dopaminergic cells against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neuroinflammation in vitro and in vivo. Biol Pharm Bull. 2012;35:1287-94 pubmed
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产品信息
产品编号 :
ADI-900-001
目录代码 :
ADI-900-001
产品名称 :
PGE2酶联免疫吸附试剂盒
产品类型 :
Kit
规格 :
96 wells
Pubmed号列表 :
26669765, 26407316, 26371857, 26348267, 26288136, 26192807, 25927603, 25909857, 25806080, 25776499
产品描述 :
The PGE2 EIA kit is a colorimetric competitive enzyme immunoassay kit with results in 2. Commercially available since 1992, this kit is widely cited in peer-reviewed publications. The non-radioactive ready-to-use liquid color-coded reagents reduce errors.
物种活性 :
Species independent
背景 :
Prostaglandin E2 (PGE2) is an extensively studied prostaglandin owing to its predominance in inflammation, cancer, atherosclerosis, autoimmune disease, and sepsis. Oxidation of arachidonic acid by prostaglandin synthases (COX-1 and COX-2) produces prostaglandin H2 (PGH2), which is further metabolized by PGE synthases into its major product, PGE2. PGE2 mediates autocrine and paracrine signaling by binding to G-protein coupled receptors (EP1, EP2, EP3, EP4) on the cell surface, functioning to modulate phospholipase C and adenylate cyclase activity. PGE2 has been of great interest as a therapeutic target, either by modulation of its synthesis by COX inhibitors (NSAIDS) or by modulation of its receptors by downregulation or binding antagonists. PGE2 production in a variety of tissues has been shown to modulate numerous physiological processes including natriuresis in the kidney, smooth muscle elasticity in the vasculature, and the inflammatory response to damaged tissues by monocytes and macrophages.
别名 :
前列腺素E2
用途 :
For the quantitative determination of PGE2 in culture supernatants, serum, saliva, urine, and whole blood from any species. Cited sample types include cerebral spinal fluid, dialysate, gingival crevicular fluid, peritoneal exudate fluid and peritoneal exudate cell supernatant, plasma, and tissue.
应用摘要 :
ELISA, Colorimetric detection
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。