产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
ELISA/assay
产品名称 :
骨桥蛋白(啮齿类), 酶联免疫吸附试剂盒
目录 :
ADI-900-090A
规格 :
96 wells
价格 :
494美元
更多信息或购买 :
文章摘录数: 4
参考文献
Carlos C, Sonehara N, Oliani S, Burdmann E. Predictive usefulness of urinary biomarkers for the identification of cyclosporine A-induced nephrotoxicity in a rat model. PLoS ONE. 2014;9:e103660 pubmed 出版商
Lyle A, Remus E, Fan A, LASSEGUE B, Walter G, Kiyosue A, et al. Hydrogen peroxide regulates osteopontin expression through activation of transcriptional and translational pathways. J Biol Chem. 2014;289:275-85 pubmed 出版商
Topkoru B, Altay O, Duris K, Krafft P, Yan J, Zhang J. Nasal administration of recombinant osteopontin attenuates early brain injury after subarachnoid hemorrhage. Stroke. 2013;44:3189-94 pubmed 出版商
Narisawa S, Yadav M, Millan J. In vivo overexpression of tissue-nonspecific alkaline phosphatase increases skeletal mineralization and affects the phosphorylation status of osteopontin. J Bone Miner Res. 2013;28:1587-98 pubmed 出版商
产品信息
产品编号 :
ADI-900-090A
目录代码 :
ADI-900-090A
产品名称 :
骨桥蛋白(啮齿类), 酶联免疫吸附试剂盒
产品类型 :
Kit
规格 :
96 wells
标价(美元) :
494美元
Pubmed号列表 :
24247243, 24008574, 23427088
产品描述 :
The Osteopontin (rodent), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 3 hours.
物种活性 :
小鼠, 大鼠
背景 :
Osteopontin (OPN) is an acidic extracellular matrix cell adhesion protein that is relatively abundant not only in bone matrix, plasma, urine, and milk, but is also found in malignant and atherogenic tissues. Phosphorylation, glycosylation and calcium modifications allow intact and fragmented Osteopontin to direct a variety of diverse responses including tissue remodeling, inflammation and cell survival. Plasma Osteopontin has been shown to be a positive indicator of colon and lung cancers as well as metastatic carcinomas. The notable presence of Osteopontin in a variety of tumors is strongly correlated to pathological stage, suggesting its critical role in tumor invasiveness, progression and metastasis. In addition, Osteopontin inhibits inducible nitric oxide synthase activity, thereby protecting tumor cells from NO-mediated macrophage cytotoxic attack. Osteopontin is found in atherosclerotic plaques and may drive a number of diabetic vascular pathologies.
别名 :
OPN, SPP1, Secreted phosphoprotein 1, Bone sialoprotein 1
用途 :
For the quantitative determination of mouse and rat osteopontin in culture supernatants, plasma, and urine. Cited sample type includes cerebrospinal fluid.
应用摘要 :
ELISA, Colorimetric detection
储存 :
+4°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。