产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
ELISA/assay
产品名称 :
Direct 8-iso-PGF2α ELISA kit
目录 :
ADI-900-091
规格 :
96 wells
价格 :
365美元
更多信息或购买 :
文章摘录数: 10
参考文献
Johnston P, McCance D, Holmes V, Young I, McGinty A. Placental antioxidant enzyme status and lipid peroxidation in pregnant women with type 1 diabetes: The effect of vitamin C and E supplementation. J Diabetes Complications. 2016;30:109-14 pubmed 出版商
Duffy M, O Kane C, Stevenson M, Young I, Harkin D, Mullan B, et al. A randomized clinical trial of ascorbic acid in open abdominal aortic aneurysm repair. Intensive Care Med Exp. 2015;3:50 pubmed 出版商
Kumar R, Kohli S, Ali Z, Duhan K, Ram R, Gupta M, et al. CYBA (p22phox) variants associate with blood pressure and oxidative stress markers in hypertension: a replication study in populations of diverse altitudes. Hypertens Res. 2015;38:498-506 pubmed 出版商
Li P, Tong Y, Yang H, Zhou S, Xiong F, Huo T, et al. Mitochondrial translocation of human telomerase reverse transcriptase in cord blood mononuclear cells of newborns with gestational diabetes mellitus mothers. Diabetes Res Clin Pract. 2014;103:310-8 pubmed 出版商
Fang H, Lin W. Lipid peroxidation products do not activate hepatic stellate cells. Toxicology. 2008;253:36-45 pubmed 出版商
Puthucheary S, Nathan S. Comparison of serum F2 isoprostane levels in diabetic patients and diabetic patients infected with Burkholderia pseudomallei. Singapore Med J. 2008;49:117-20 pubmed
Jeanes Y, Hall W, Proteggente A, Lodge J. Cigarette smokers have decreased lymphocyte and platelet alpha-tocopherol levels and increased excretion of the gamma-tocopherol metabolite gamma-carboxyethyl-hydroxychroman (gamma-CEHC). Free Radic Res. 2004;38:861-8 pubmed
Patel M, Bhat H. Differential oxidant potential of carcinogenic and weakly carcinogenic estrogens: Involvement of metabolic activation and cytochrome P450. J Biochem Mol Toxicol. 2004;18:37-42 pubmed
Hoffman Goetz L, Quadrilatero J. Treadmill exercise in mice increases intestinal lymphocyte loss via apoptosis. Acta Physiol Scand. 2003;179:289-97 pubmed
Bhat H, Calaf G, Hei T, Loya T, Vadgama J. Critical role of oxidative stress in estrogen-induced carcinogenesis. Proc Natl Acad Sci U S A. 2003;100:3913-8 pubmed
产品信息
产品编号 :
ADI-900-091
目录代码 :
ADI-900-091
产品名称 :
Direct 8-iso-PGF2α ELISA kit
产品类型 :
Kit
规格 :
96 wells
标价(美元) :
365美元
Pubmed号列表 :
26597598, 26215814, 25787042, 24480248, 18789371, 18301838, 15493460, 14994278, 14616245, 12655060
产品描述 :
The measurement of F2-isoprostanes has emerged as one of the most reliable approaches to assess oxidative stress status in vivo, providing an important tool to explore the role of oxidative stress in the pathogenesis of human disease. The is a colorimetric competitive immunoassay kit for the quantitative determination of 8-iso-Prostaglandin F2α in biological fluids such as plasma, serum and tissue. To measure isoprostane in urine or culture supernatants, use the 8-iso-PGF2α EIA Kit. 8-iso-PGF2α is produced in vivo by both non-cyclooxygenase and cyclooxygenase dependant mechanisms from arachidonic acid. It has been shown to be a potent vasoconstrictor, a potential mediator of hepatorenal syndrome and a mutagen in 3T3 cells and vascular smooth muscle cells. 8-iso-PGF2α has been shown to circulate in plasma and is excreted in urine.
物种活性 :
Species independent
背景 :
Prostaglandin F2α (PGF2α) is formed in a variety of cells from PGH2, which itself is synthesized from arachidonic acid by the enzyme prostaglandin synthetase. PGF2α is often viewed as an antagonist to PGE2 due to their opposing effects on various tissues. PGF2α is a potent bronchoconstrictor and has been implicated in asthma attacks. PGF2α is also involved in reproductive functions including corpus luteum regulation, uterine contractions, and sperm motility. This has led to its use in terminating pregnancies and inducing labor at term. High levels of PGF2α have also been associated with preeclampsia.
别名 :
8-iso-Prostaglandin F2α
用途 :
For the quantitative determination of 8-iso-PGF2α in plasma, serum, and tissue from any species. Cited sample types include cell lysate and urine.
应用摘要 :
ELISA, Colorimetric detection
储存 :
+4°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。