产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
ELISA/assay
产品名称 :
13(S)-HODE酶联免疫吸附试剂盒
目录 :
ADI-900-108
规格 :
96 wells
更多信息或购买 :
文章摘录数: 2
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Coleman J, Prabhu K, Thompson J, Reddy P, Peters J, Peterson B, et al. The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). Free Radic Biol Med. 2007;42:1155-64 pubmed
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Shureiqi I, Zuo X, Broaddus R, Wu Y, Guan B, Morris J, et al. The transcription factor GATA-6 is overexpressed in vivo and contributes to silencing 15-LOX-1 in vitro in human colon cancer. FASEB J. 2007;21:743-53 pubmed
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产品信息
产品编号 :
ADI-900-108
目录代码 :
ADI-900-108
产品名称 :
13(S)-HODE酶联免疫吸附试剂盒
产品类型 :
Kit
规格 :
96 wells
Pubmed号列表 :
17382197, 17167069
产品描述 :
The 13(S)-HODE EIA kit is a colorimetric competitive enzyme immunoassay kit with results in 4 hours. Absorbance is read at 405 nm. The kit provides ready-to-use non-radioactive liquid color-coded reagents that reduce error in the lab.
物种活性 :
Species independent
背景 :
The major human dietary poly-unsaturated fatty acid is linoleic acid, an essential fatty acid that can be metabolized to either 13-hydroxyoctadecadienoic acid [13(S)-HODE] via lipoxygenase or [13(R)-HODE] by p450 enzymes. Alternatively, cyclooxygenase metabolism of linoleic acid results in the production of hydroxyeicosatetraenoic acid [15(S)-HETE]. Changes in the intra-cellular ratio of 13(S)-HODE to 15(S)-HETE have been linked to a number of physiological conditions including cancer and cardiovascular disease. 13(S)-HODE helps to mediate cell adhesion and excessive proliferation that is critical in the formation of tumors and metastases, as well as the formation of atherogenic plaques.
别名 :
13-hydroxyoctadecadienoic acid
用途 :
For the quantitative determination of 13(S)-HODE in culture supernatants, cell lysates, serum, saliva, tissue, and urine from any species. Cited sample type includes plasma (ref. 1).
应用摘要 :
ELISA, Colorimetric detection
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com1-800-942-0430
公司总部: 美国
自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。