骨桥蛋白(人类), 酶联免疫吸附试剂盒 | Enzo Life Sciences ADI-900-142 产品信息

产品简要

公司名称 :

Enzo Life Sciences

其他品牌 :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

产品类型 :

ELISA/assay

产品名称 :

骨桥蛋白(人类), 酶联免疫吸附试剂盒

ADI-900-142

规格 :

96 wells

更多信息或购买 :

Enzo Life Sciences 产品网页

文章摘录数: 6

参考文献
Anborgh P, Caria L, Chambers A, Tuck A, Stitt L, Brackstone M. Role of plasma osteopontin as a biomarker in locally advanced breast cancer. Am J Transl Res. 2015;7:723-32 pubmed
Bramwell V, Tuck A, Chapman J, Anborgh P, Postenka C, Al Katib W, et al. Assessment of osteopontin in early breast cancer: correlative study in a randomised clinical trial. Breast Cancer Res. 2014;16:R8 pubmed 出版商
Francia P, Adduci C, Semprini L, Borro M, Ricotta A, Sensini I, et al. Osteopontin and galectin-3 predict the risk of ventricular tachycardia and fibrillation in heart failure patients with implantable defibrillators. J Cardiovasc Electrophysiol. 2014;25:609-16 pubmed 出版商
Kivisakk P, Healy B, Francois K, Gandhi R, Gholipour T, Egorova S, et al. Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development. Mult Scler. 2014;20:438-44 pubmed 出版商
Karadag F, Gulen S, Karul A, Kilicarslan N, Ceylan E, Kuman N, et al. Osteopontin as a marker of weight loss in lung cancer. Scand J Clin Lab Invest. 2011;71:690-4 pubmed 出版商
Tang C, Huang T, Chang C, Fu W, Yang R. Water solution of onion crude powder inhibits RANKL-induced osteoclastogenesis through ERK, p38 and NF-kappaB pathways. Osteoporos Int. 2009;20:93-103 pubmed 出版商

产品信息

产品编号 :

ADI-900-142

目录代码 :

ADI-900-142

产品名称 :

骨桥蛋白(人类), 酶联免疫吸附试剂盒

产品类型 :

Kit

规格 :

96 wells

Pubmed号列表 :

26064440, 24451146, 24400815, 24005026, 22017168, 18506384

产品描述 :

The Osteopontin (human), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 3 hours. Absorbance is read at 450 nm. Ready-to-use liquid color-coded reagents reduce error. Excellent publications in peer-reviewed publications demonstrate the utility and consistency of this kit developed with highly cited double monoclonal antibodies.

物种活性 :

人类

背景 :

Osteopontin (OPN) is an acidic extracellular matrix cell adhesion protein that is relatively abundant not only in bone matrix, plasma, urine, and milk, but is also found in malignant and atherogenic tissues. Phosphorylation, glycosylation and calcium modifications allow intact and fragmented Osteopontin to direct a variety of diverse responses including tissue remodeling, inflammation and cell survival. Plasma Osteopontin has been shown to be a positive indicator of colon and lung cancers as well as metastatic carcinomas. The notable presence of Osteopontin in a variety of tumors is strongly correlated to pathological stage, suggesting its critical role in tumor invasiveness, progression and metastasis. In addition, Osteopontin inhibits inducible nitric oxide synthase activity, thereby protecting tumor cells from NO-mediated macrophage cytotoxic attack. Osteopontin is found in atherosclerotic plaques and may drive a number of diabetic vascular pathologies.

别名 :

OPN, SPP1, Secreted phosphoprotein 1, Bone sialoprotein 1

用途 :

For the quantitative determination of human Osteopontin in culture supernatants, milk, plasma, and urine. Cited sample type includes serum.

应用摘要 :

ELISA, Colorimetric detection

更多信息或购买 :

Enzo Life Sciences 产品网页

公司信息

Enzo Life Sciences

5777 Hines Drive
Ann Arbor, MI 48108

techserv-usa@enzolifesciences.com

https://www.enzolifesciences.com

1-800-942-0430

公司总部: 美国

自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。