Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

抗体

Jnk1单克隆抗体(1C2)

ADI-905-862-100

100微升

单克隆

小鼠

未共轭

1C2

人类, 小鼠

ADI-905-862-100

Jnk1单克隆抗体(1C2)

小鼠

单克隆

抗体

100微升

1C2

IgG2a

人类, 小鼠

JNK1 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK1 is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of JNK1 by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. JNK1 is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of JNK1 gene suggested that it play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

c Jun氨基末端激酶1, SAP激酶1c, SAPK1c, 地图激酶8, MAPK8

重组人类Jnk1(氨基酸1-384)

液体。 在PBS, pH值7.3, 含1% BSA, 50% 甘油和0.02% 叠氮化钠

Detects a band of ~45kDa (full length) by Western blot.

免疫印迹

-20°C