产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶3多克隆抗体
目录 :
ADI-AAP-113-F
规格 :
200微克
价格 :
338美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠, , ,
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
文章摘录数: 8
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 人类; 图 1g
Seo B, Min K, Woo S, Choe M, Choi K, Lee Y, et al. Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP. Antioxid Redox Signal. 2017;27:215-233 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Wang C, Guo S, Wang J, Yan X, Farrelly M, Zhang Y, et al. Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922. Oncotarget. 2016;7:49597-49610 pubmed 出版商
Park E, Min K, Choi K, Kubatka P, Kruzliak P, Kim D, et al. Chloroquine enhances TRAIL-mediated apoptosis through up-regulation of DR5 by stabilization of mRNA and protein in cancer cells. Sci Rep. 2016;6:22921 pubmed 出版商
Hu W, Jin L, Jiang C, Long G, Scolyer R, Wu Q, et al. AEBP1 upregulation confers acquired resistance to BRAF (V600E) inhibition in melanoma. Cell Death Dis. 2013;4:e914 pubmed 出版商
Giansanti V, Rodriguez G, Savoldelli M, Gioia R, Forlino A, Mazzini G, et al. Characterization of stress response in human retinal epithelial cells. J Cell Mol Med. 2013;17:103-15 pubmed 出版商
Zang Y, Thomas S, Chan E, Kirk C, Freilino M, Delancey H, et al. Carfilzomib and ONX 0912 inhibit cell survival and tumor growth of head and neck cancer and their activities are enhanced by suppression of Mcl-1 or autophagy. Clin Cancer Res. 2012;18:5639-49 pubmed 出版商
Decrion Barthod A, Bosset M, Plissonnier M, Marchini A, Nicolier M, Launay S, et al. Sodium butyrate with UCN-01 has marked antitumour activity against cervical cancer cells. Anticancer Res. 2010;30:4049-61 pubmed
Rao N, Saraswathy S, Wu G, Katselis G, Wawrousek E, Bhat S. Elevated retina-specific expression of the small heat shock protein, alphaA-crystallin, is associated with photoreceptor protection in experimental uveitis. Invest Ophthalmol Vis Sci. 2008;49:1161-71 pubmed 出版商
产品信息
产品编号 :
ADI-AAP-113
目录代码 :
ADI-AAP-113-F
产品名称 :
胱氨酸-天冬氨酸蛋白酶3多克隆抗体
宿主物种 :
克隆性 :
多克隆
产品类型 :
抗体
规格 :
200微克
标价(美元) :
338美元
Pubmed号列表 :
24201813, 23205553, 22929803, 21036719, 18326745, 12665479, 11980894, 11976344
物种活性 :
Human, Mouse, Rat, Yeast, Rabbit, Porcine, Monkey, Hamster, Guinea pig, Dog, Chicken, Bovine
背景 :
The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.
免疫原 :
重组人类胱氨酸-天冬氨酸蛋白酶3蛋白(全长)
缓冲液 :
Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
用途 :
Detects a band of ~36kDa by Western blot. A lower molecular weight band refers to a proteolytic cleavage product of caspase-3.
应用摘要 :
免疫组化(PS), 免疫印迹
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。