Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

抗体

肿瘤坏死因子受体1多克隆抗体

ADI-CSA-815-D

50微克

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠, 犬, 牛

免疫印迹, 免疫组化, 免疫沉淀

ADI-CSA-815-D

肿瘤坏死因子受体1多克隆抗体

兔

多克隆

抗体

50微克

12963644

Human, Mouse, Rat, Yeast, Xenopus, Sheep, Rabbit, Porcine, Monkey, Hamster, Drosophila, Dog, Bovine

Tumor necrosis factor alpha (TNF-α), also known as cachectin, is a 17.5 kDa 157 amino acid member of the TNF superfamily of cytokines that is a potent lymphoid factor with effects on a wide range of target cells. Active TNFalpha is produced in both soluble and membrane-anchored trimers by macrophages, NK cells, and T- and B-lymphocytes. TNF exerts proinflammatory signals via binding and inducing trimerization of TNF-receptor1 (TNF-R1) expressed on most normal and transformed cells, or to TNF-receptor 2 (TNF-R2), expressed on endothelial and most immune cells. TNF signaling regulates hematopeiesis, differentation, endothelial cell activation, apoptosis, lipid metabolism, tumor progression, and immune suveillance, and dysregulation of TNF or its receptors is implicated in numerous disease states including cancer, osteoporosis, autoimmune disease, diabetes, and atherosclerosis.

肿瘤坏死因子受体1, 肿瘤坏死因子-R1

Synthetic peptide corresponding to a portion of mouse TNF-R1. The sequence is completely conserved in rat and human.

液体。 在PBS含50% 甘油和0.09% 叠氮化钠

Detects a band of 55kDa by Western blot.

免疫组化(PS), 免疫沉淀, 免疫印迹

-20°C