产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
HSP60单克隆抗体(LK-1)
目录 :
ADI-SPA-806-J
规格 :
1毫克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
LK-1
反应物种 :
Garra rufa, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
Enzo Life Sciences 产品网页
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 大鼠; 1:1200
Van Laar V, Roy N, Liu A, Rajprohat S, Arnold B, Dukes A, et al. Glutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagy. Neurobiol Dis. 2015;74:180-93 pubmed 出版商
  • 免疫印迹; Garra rufa
Oksala N, Ekmekçi F, Ozsoy E, Kirankaya S, Kokkola T, Emecen G, et al. Natural thermal adaptation increases heat shock protein levels and decreases oxidative stress. Redox Biol. 2014;3:25-8 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000
Moura C, Lollo P, Morato P, Nisishima L, Carneiro E, Amaya Farfan J. Whey protein hydrolysate enhances HSP90 but does not alter HSP60 and HSP25 in skeletal muscle of rats. PLoS ONE. 2014;9:e83437 pubmed 出版商
Pharaoh G, Pulliam D, Hill S, Sataranatarajan K, Van Remmen H. Ablation of the mitochondrial complex IV assembly protein Surf1 leads to increased expression of the UPR(MT) and increased resistance to oxidative stress in primary cultures of fibroblasts. Redox Biol. 2016;8:430-8 pubmed 出版商
Kasza A, Hunya A, Frank Z, Fulop F, Torok Z, Balogh G, et al. Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2016;53:557-71 pubmed 出版商
Tamura Y, Matsunaga Y, Kitaoka Y, Hatta H. Effects of Heat Stress Treatment on Age-dependent Unfolded Protein Response in Different Types of Skeletal Muscle. J Gerontol A Biol Sci Med Sci. 2017;72:299-308 pubmed 出版商
Wichmann H, Vocke F, Brinkhoff T, Simon M, Richter Landsberg C. Cytotoxic Effects of Tropodithietic Acid on Mammalian Clonal Cell Lines of Neuronal and Glial Origin. Mar Drugs. 2015;13:7113-23 pubmed 出版商
Kratochwill K, Bender T, Lichtenauer A, Herzog R, Tarantino S, Bialas K, et al. Cross-omics comparison of stress responses in mesothelial cells exposed to heat- versus filter-sterilized peritoneal dialysis fluids. Biomed Res Int. 2015;2015:628158 pubmed 出版商
Kumar Singh M, Janardhan Reddy P, Sreedhar A, Tiwari P. Molecular characterization and expression analysis of hsp60 gene homologue of sheep blowfly, Lucilia cuprina. J Therm Biol. 2015;52:24-37 pubmed 出版商
Tamura Y, Kitaoka Y, Matsunaga Y, Hoshino D, Hatta H. Daily heat stress treatment rescues denervation-activated mitochondrial clearance and atrophy in skeletal muscle. J Physiol. 2015;593:2707-20 pubmed 出版商
Tamura Y, Matsunaga Y, Masuda H, Takahashi Y, Takahashi Y, Terada S, et al. Postexercise whole body heat stress additively enhances endurance training-induced mitochondrial adaptations in mouse skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2014;307:R931-43 pubmed 出版商
Zhang X, He M, Cheng L, Chen Y, Zhou L, Zeng H, et al. Elevated heat shock protein 60 levels are associated with higher risk of coronary heart disease in Chinese. Circulation. 2008;118:2687-93 pubmed 出版商
Horiguchi Y, Araki M, Motojima K. Identification and characterization of the ER/lipid droplet-targeting sequence in 17beta-hydroxysteroid dehydrogenase type 11. Arch Biochem Biophys. 2008;479:121-30 pubmed 出版商
Ren J, Agata N, Chen D, Li Y, Yu W, Huang L, et al. Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents. Cancer Cell. 2004;5:163-75 pubmed
产品信息
产品编号 :
ADI-SPA-806
目录代码 :
ADI-SPA-806-J
产品名称 :
HSP60单克隆抗体(LK-1)
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
抗体
规格 :
1毫克
Pubmed号列表 :
26633426, 26495307, 26267495, 25080501, 19106391, 18804447, 14998492
克隆 :
LK-1
抗体亚型 :
IgG1
物种活性 :
Human, Mouse, Rat, Xenopus, Sheep, Rabbit, Porcine, Monkey, Hamster, Guinea pig, Drosophila, Dog, Chicken, Bovine
背景 :
Hsp60 is a member of the chaperonin family of heat shock proteins, with homologs functioning in the cytosol and mitochondria to fold nascent and aggregated proteins. Hsp60 is the eukaryotic homolog of the E. coli GroEL protein, and forms a multimeric complex in the mitochondria with Hsp10 (Cpn10) to form a large central cavity in which ATP-dependent protein folding takes place. TRiC/CCT, a eukaryotic relative of Hsp60, is expressed in the cytosol and participates in the folding of actin and tubulin substrates, but lacks any association with an Hsp10-like co-factor.
别名 :
分子伴侣60, CPN60, HspD1, 热休克蛋白60
免疫原 :
重组人类Hsp60
缓冲液 :
液体。 在PBS, pH值7.2, 含50% 甘油和0.09% 叠氮化钠
用途 :
Detects a band of ~60kDa by Western blot.
应用摘要 :
酶联免疫吸附测定, FC, IF, 免疫组化(PS), 免疫沉淀, 免疫印迹
储存 :
-20°C
更多信息或购买 :
Enzo Life Sciences 产品网页
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。