产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
HSP60单克隆抗体(LK-2)
目录 :
ADI-SPA-807-E
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
LK-2
反应物种 :
African green monkey, , 人类, 小鼠, 大鼠, 牛
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
Enzo Life Sciences 产品网页
文章摘录数: 15
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 小鼠; 1:5000; 图 2b
  • 免疫细胞化学; 人类; 1:5000; 图 1b
  • 免疫细胞化学; African green monkey; 1:5000; 图 1d
Newman L, Schiavon C, Zhou C, Kahn R. The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors. PLoS ONE. 2017;12:e0175164 pubmed 出版商
  • 免疫细胞化学; 人类; 1:5000; 图 2
Newman L, Schiavon C, Kahn R. Plasmids for variable expression of proteins targeted to the mitochondrial matrix or intermembrane space. Cell Logist. 2016;6:e1247939 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 1
Nilsen T, Thorsen L, Kirkegaard C, Ugelstad I, Fossa S, Raastad T. The effect of strength training on muscle cellular stress in prostate cancer patients on ADT. Endocr Connect. 2016;5:74-82 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 3
Heiserman J, Chen L, Kim B, Kim S, Tran A, Siebenborn N, et al. TLR4 mutation and HSP60-induced cell death in adult mouse cardiac myocytes. Cell Stress Chaperones. 2015;20:527-35 pubmed 出版商
Fischer F, Filippis C, Osiewacz H. RCF1-dependent respiratory supercomplexes are integral for lifespan-maintenance in a fungal ageing model. Sci Rep. 2015;5:12697 pubmed 出版商
Ortega A, Sala S, Espinosa E, Gonzalez Baron M, Cuezva J. HuR and the bioenergetic signature of breast cancer: a low tumor expression of the RNA-binding protein predicts a higher risk of disease recurrence. Carcinogenesis. 2008;29:2053-61 pubmed 出版商
Alam T, Kanki T, Muta T, Ukaji K, Abe Y, Nakayama H, et al. Human mitochondrial DNA is packaged with TFAM. Nucleic Acids Res. 2003;31:1640-5 pubmed
Wang X, Wang D, Zhu W, Delrahim K, Dolnak D, Rapaport M. Studies characterizing 60 kda autoantibodies in subjects with schizophrenia. Biol Psychiatry. 2003;53:361-75 pubmed
Satoh M, Hamamoto T, Seo N, Kagawa Y, Endo H. Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria. Biochem Biophys Res Commun. 2003;300:482-93 pubmed
Tabeta K, Yamazaki K, Hotokezaka H, Yoshie H, Hara K. Elevated humoral immune response to heat shock protein 60 (hsp60) family in periodontitis patients. Clin Exp Immunol. 2000;120:285-93 pubmed
Belles C, Kuhl A, Nosheny R, Carding S. Plasma membrane expression of heat shock protein 60 in vivo in response to infection. Infect Immun. 1999;67:4191-200 pubmed
Giraldo P, Neuer A, Korneeva I, Ribeiro Filho A, Simoes J, Witkin S. Vaginal heat shock protein expression in symptom-free women with a history of recurrent vulvovaginitis. Am J Obstet Gynecol. 1999;180:524-9 pubmed
Zhang Y, Ohashi N, Lee E, Tamura A, Rikihisa Y. Ehrlichia sennetsu groE operon and antigenic properties of the GroEL homolog. FEMS Immunol Med Microbiol. 1997;18:39-46 pubmed
Munoz M, Jeremias J, Witkin S. The 60 kDa heat shock protein in human semen: relationship with antibodies to spermatozoa and Chlamydia trachomatis. Hum Reprod. 1996;11:2600-3 pubmed
Boog C, de Graeff Meeder E, Lucassen M, van der Zee R, Voorhorst Ogink M, van Kooten P, et al. Two monoclonal antibodies generated against human hsp60 show reactivity with synovial membranes of patients with juvenile chronic arthritis. J Exp Med. 1992;175:1805-10 pubmed
产品信息
产品编号 :
ADI-SPA-807
目录代码 :
ADI-SPA-807-E
产品名称 :
HSP60单克隆抗体(LK-2)
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
抗体
规格 :
100微克
Pubmed号列表 :
18687667, 12626705, 12614989, 12504110, 10792378, 10417191, 10076122, 9215585, 9021358, 1316935
克隆 :
LK-2
抗体亚型 :
IgG1
物种活性 :
Human, Mouse, Rat, Ehrlichia sennetsu, Rabbit, Plant, Porcine, Monkey, Hamster, Guinea pig, Dog, Chicken, C. elegans, Bovine
背景 :
Hsp60 is a member of the chaperonin family of heat shock proteins, with homologs functioning in the cytosol and mitochondria to fold nascent and aggregated proteins. Hsp60 is the eukaryotic homolog of the E. coli GroEL protein, and forms a multimeric complex in the mitochondria with Hsp10 (Cpn10) to form a large central cavity in which ATP-dependent protein folding takes place. TRiC/CCT, a eukaryotic relative of Hsp60, is expressed in the cytosol and participates in the folding of actin and tubulin substrates, but lacks any association with an Hsp10-like co-factor.
别名 :
分子伴侣60, CPN60, HspD1, 热休克蛋白60
免疫原 :
重组人类HSP60
缓冲液 :
液体。 在PBS, pH值7.2, 含0.1mM苯甲基磺酰氟和50% 甘油
用途 :
Detects a band of ~60kDa by Western blot.
应用摘要 :
酶联免疫吸附测定, FC, 免疫组化, 免疫沉淀, 免疫印迹
储存 :
-20°C
更多信息或购买 :
Enzo Life Sciences 产品网页
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。