产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
溶酶体相关膜蛋白质1单克隆抗体(Ly1C6)
目录 :
ADI-VAM-EN001-D
规格 :
50微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
Ly1C6
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
Enzo Life Sciences 产品网页
文章摘录数: 18
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 大鼠; 1:100; 图 8c
Wolfes A, Ahmed S, Awasthi A, Stahlberg M, Rajput A, Magruder D, et al. A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes. J Gen Physiol. 2017;149:149-170 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1 ug/ml; 图 2c
Kawahara K, Hirata H, Ohbuchi K, Nishi K, Maeda A, Kuniyasu A, et al. The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin-like protease(s) in a subpopulation of microglia in neonatal rat brain. Glia. 2016;64:1938-61 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 2
Dobrinskikh E, Lewis L, Brian Doctor R, Okamura K, Lee M, Altmann C, et al. Shank2 Regulates Renal Albumin Endocytosis. Physiol Rep. 2015;3: pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 2
Kaushik S, Cuervo A. Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis. Nat Cell Biol. 2015;17:759-70 pubmed 出版商
  • 免疫细胞化学; 小鼠
Underhill S, Wheeler D, Amara S. Differential regulation of two isoforms of the glial glutamate transporter EAAT2 by DLG1 and CaMKII. J Neurosci. 2015;35:5260-70 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 5a
Widagdo J, Chai Y, Ridder M, Chau Y, Johnson R, Sah P, et al. Activity-Dependent Ubiquitination of GluA1 and GluA2 Regulates AMPA Receptor Intracellular Sorting and Degradation. Cell Rep. 2015;10:783-795 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Bejarano E, Yuste A, Patel B, Stout R, Spray D, Cuervo A. Connexins modulate autophagosome biogenesis. Nat Cell Biol. 2014;16:401-14 pubmed 出版商
Huang T, Zhao Y, Li X, Wang X, Tseng I, Thompson R, et al. SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein. J Neurosci. 2016;36:7996-8011 pubmed 出版商
Hou Y, Ernst S, Stuenkel E, Lentz S, Williams J. Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion. PLoS ONE. 2015;10:e0125596 pubmed 出版商
Rong Y, Liu M, Ma L, Du W, Zhang H, Tian Y, et al. Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation. Nat Cell Biol. 2012;14:924-34 pubmed 出版商
Thomas D, Martin C, Weng N, Byrne J, Groblewski G. Tumor protein D52 expression and Ca2+-dependent phosphorylation modulates lysosomal membrane protein trafficking to the plasma membrane. Am J Physiol Cell Physiol. 2010;298:C725-39 pubmed 出版商
Grampp T, Notz V, Broll I, Fischer N, Benke D. Constitutive, agonist-accelerated, recycling and lysosomal degradation of GABA(B) receptors in cortical neurons. Mol Cell Neurosci. 2008;39:628-37 pubmed 出版商
Daniele T, Di Tullio G, Santoro M, Turacchio G, De Matteis M. ARAP1 regulates EGF receptor trafficking and signalling. Traffic. 2008;9:2221-35 pubmed 出版商
Wreden C, Johnson J, Tran C, Seal R, Copenhagen D, Reimer R, et al. The H+-coupled electrogenic lysosomal amino acid transporter LYAAT1 localizes to the axon and plasma membrane of hippocampal neurons. J Neurosci. 2003;23:1265-75 pubmed
Sans N, Racca C, Petralia R, Wang Y, McCallum J, Wenthold R. Synapse-associated protein 97 selectively associates with a subset of AMPA receptors early in their biosynthetic pathway. J Neurosci. 2001;21:7506-16 pubmed
Isobe I, Yanagisawa K, Michikawa M. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) causes Akt phosphorylation and morphological changes in intracellular organellae in cultured rat astrocytes. J Neurochem. 2001;77:274-80 pubmed
Lewis V, Green S, Marsh M, Vihko P, Helenius A, Mellman I. Glycoproteins of the lysosomal membrane. J Cell Biol. 1985;100:1839-47 pubmed
Harter C, Mellman I. Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane. J Cell Biol. 1992;117:311-25 pubmed
产品信息
产品编号 :
ADI-VAM-EN001
目录代码 :
ADI-VAM-EN001-D
产品名称 :
溶酶体相关膜蛋白质1单克隆抗体(Ly1C6)
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
抗体
规格 :
50微克
Pubmed号列表 :
22885770, 20032513, 18948198, 18764928, 12598615, 11567040, 11279283, 3922993, 1560028
克隆 :
LY1C6
抗体亚型 :
IgG1
物种活性 :
人类, 大鼠, 仓鼠
背景 :
Lysosome-associated membrane proteins (LAMP1 and LAMP2) are type I integral membrane protein that are transported from the trans-Golgi network to endosomes and then lysosomes. Following activation of platelets, T-cells, neutrophils, or endothelium, LAMP1 and LAMP2 are expressed on the cell surface. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, and loss of LAMP2 expression is associated with impaired autophagy observed in Danons disease.
别名 :
溶酶体相关膜蛋白1
免疫原 :
Rat liver lysosomal membrane preparation.
缓冲液 :
液体。 在PBS含50% 甘油和0.09% 叠氮化钠
用途 :
Detects a band of ~120kDa by Western blot.
应用摘要 :
免疫细胞化学, IF, 免疫沉淀, 免疫印迹, 电子显微镜
储存 :
-20°C
更多信息或购买 :
Enzo Life Sciences 产品网页
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。