产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
蛋白
产品名称 :
Z-VAD-FMK
目录 :
ALX-260-020-M005
规格 :
5毫克
更多信息或购买 :
文章摘录数: 18
参考文献
Jung S, Choe S, Woo H, Jeong H, An H, Moon H, et al. Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits. Autophagy. 2019;:1-19 pubmed 出版商
Monian P, Jiang X. The Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell Proliferation. J Biol Chem. 2016;291:2379-88 pubmed 出版商
Amiel A, Johnston H, Nedoncelle K, Warner J, Ferreira S, Röttinger E. Characterization of Morphological and Cellular Events Underlying Oral Regeneration in the Sea Anemone, Nematostella vectensis. Int J Mol Sci. 2015;16:28449-71 pubmed 出版商
Yadav N, Kumar S, Kumar R, Srivastava P, Sun L, Rapali P, et al. Mechanism of neem limonoids-induced cell death in cancer: Role of oxidative phosphorylation. Free Radic Biol Med. 2016;90:261-71 pubmed 出版商
Uesugi S, Fujisawa N, Yoshida J, Watanabe M, Dan S, Yamori T, et al. Pyrrocidine A, a metabolite of endophytic fungi, has a potent apoptosis-inducing activity against HL60 cells through caspase activation via the Michael addition. J Antibiot (Tokyo). 2016;69:133-40 pubmed 出版商
Mahul Mellier A, Vercruysse F, Maco B, Ait Bouziad N, de Roo M, Muller D, et al. Fibril growth and seeding capacity play key roles in α-synuclein-mediated apoptotic cell death. Cell Death Differ. 2015;22:2107-22 pubmed 出版商
Berthou F, Ceppo F, Dumas K, Massa F, Vergoni B, Alemany S, et al. The Tpl2 Kinase Regulates the COX-2/Prostaglandin E2 Axis in Adipocytes in Inflammatory Conditions. Mol Endocrinol. 2015;29:1025-36 pubmed
Schüll S, Günther S, Brodesser S, Seeger J, Tosetti B, Wiegmann K, et al. Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6. Cell Death Dis. 2015;6:e1691 pubmed 出版商
Colin D, Hain K, Allan L, Clarke P. Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins. Open Biol. 2015;5:140156 pubmed 出版商
Pfister A, Keil M, Kühl M. The Wnt Target Protein Peter Pan Defines a Novel p53-independent Nucleolar Stress-Response Pathway. J Biol Chem. 2015;290:10905-18 pubmed 出版商
Liang J, Martinez A, Lane J, Mayor U, Clague M, Urbé S. USP30 deubiquitylates mitochondrial Parkin substrates and restricts apoptotic cell death. EMBO Rep. 2015;16:618-27 pubmed 出版商
Moriwaki K, Bertin J, Gough P, Orlowski G, Chan F. Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death. Cell Death Dis. 2015;6:e1636 pubmed 出版商
Cao Z, Li X, Zou X, Greenwood M, Gerwick W, Murray T. Involvement of JNK and caspase activation in hoiamide A-induced neurotoxicity in neocortical neurons. Mar Drugs. 2015;13:903-19 pubmed 出版商
Woolbright B, Dorko K, Antoine D, Clarke J, Gholami P, Li F, et al. Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis. Toxicol Appl Pharmacol. 2015;283:168-77 pubmed 出版商
Schilling J, Machkovech H, He L, Diwan A, Schaffer J. TLR4 activation under lipotoxic conditions leads to synergistic macrophage cell death through a TRIF-dependent pathway. J Immunol. 2013;190:1285-96 pubmed 出版商
Gangopadhyay N, Luketich J, Opest A, Visus C, Meyer E, Landreneau R, et al. Inhibition of poly(ADP-ribose) polymerase (PARP) induces apoptosis in lung cancer cell lines. Cancer Invest. 2011;29:608-16 pubmed 出版商
Fujita M, Yagami T, Fujio M, Tohji C, Takase K, Yamamoto Y, et al. Cytotoxicity of troglitazone through PPAR?-independent pathway and p38 MAPK pathway in renal cell carcinoma. Cancer Lett. 2011;312:219-27 pubmed 出版商
Contreras R, Sakagami H, Nakajima H, Shimada J. Type of cell death induced by various metal cations in cultured human gingival fibroblasts. In Vivo. 2010;24:513-7 pubmed
产品信息
产品编号 :
ALX-260-020
目录代码 :
ALX-260-020-M005
产品名称 :
Z-VAD-FMK
产品类型 :
多肽
规格 :
5毫克
Pubmed号列表 :
26668314, 26633371, 26627937, 26506860, 26138444, 26020725, 25766330, 25761368, 25759387, 25739811
产品描述 :
Irreversible, cell permeable broad-spectrum caspase inhibitor.
别名 :
Caspase family inhibitor (fluoromethylketone), Z-Val-Ala-DL-Asp-FMK
纯度 :
≥98%(HPLC)
用途 :
Can be used as a broad spectrum caspase inhibitor in conjunction with apoptosis detection assays.
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。