产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
化学品
产品名称 :
N-ω-Propyl-L-arginine
目录 :
ALX-270-203-M025
规格 :
25毫克
更多信息或购买 :
文章摘录数: 8
参考文献
Klamer D, ENGEL J, Svensson L. The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. Eur J Pharmacol. 2004;503:103-7 pubmed
Gowda C, Toomayan G, Qi W, Chen L, Cai Y, Allen D, et al. The effects of N(omega)-propyl-L-arginine on reperfusion injury of skeletal muscle. Nitric Oxide. 2004;11:17-24 pubmed
Fedorov R, Hartmann E, Ghosh D, Schlichting I. Structural basis for the specificity of the nitric-oxide synthase inhibitors W1400 and Nomega-propyl-L-Arg for the inducible and neuronal isoforms. J Biol Chem. 2003;278:45818-25 pubmed
Boer R, Ulrich W, Klein T, Mirau B, Haas S, Baur I. The inhibitory potency and selectivity of arginine substrate site nitric-oxide synthase inhibitors is solely determined by their affinity toward the different isoenzymes. Mol Pharmacol. 2000;58:1026-34 pubmed
Cooper G, Mialkowski K, Wolff D. Cellular and enzymatic studies of N(omega)-propyl-l-arginine and S-ethyl-N-[4-(trifluoromethyl)phenyl]isothiourea as reversible, slowly dissociating inhibitors selective for the neuronal nitric oxide synthase isoform. Arch Biochem Biophys. 2000;375:183-94 pubmed
Huang H, Martasek P, Roman L, Masters B, Silverman R. N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase. J Med Chem. 1999;42:3147-53 pubmed
Lee Y, Marletta M, Martasek P, Roman L, Masters B, Silverman R. Conformationally-restricted arginine analogues as alternative substrates and inhibitors of nitric oxide synthases. Bioorg Med Chem. 1999;7:1097-104 pubmed
Zhang H, Fast W, Marletta M, Martasek P, Silverman R. Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. J Med Chem. 1997;40:3869-70 pubmed
产品信息
产品编号 :
ALX-270-203
目录代码 :
ALX-270-203-M025
产品名称 :
N-ω-Propyl-L-arginine
产品类型 :
Biochemical
规格 :
25毫克
Pubmed号列表 :
15496304, 15350553, 12954642, 12954642, 11040050, 10683266, 10447959, 10428379, 9397167
产品描述 :
Potent and selective inhibitor of neuronal nitric oxide synthase (nNOS; NOS I) relative to inducible nitric oxide synthase (iNOS; NOS II) (3158-fold) and endothelial nitric oxide synthase (eNOS; NOS III) (149-fold).
别名 :
N5-[Imino(propylamino)methyl]-L-ornithine
纯度 :
≥98%(TLC)
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。