产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
化学品
产品名称 :
Genistein (synthetic)
目录 :
ALX-350-006-G001
规格 :
1 g
价格 :
567美元
更多信息或购买 :
文章摘录数: 10
参考文献
Breit A, Besik V, Solinski H, Muehlich S, Glas E, Yarwood S, et al. Serine-727 phosphorylation activates hypothalamic STAT-3 independently from tyrosine-705 phosphorylation. Mol Endocrinol. 2015;29:445-59 pubmed 出版商
Sarkar F, Adsule S, Padhye S, Kulkarni S, Li Y. The role of genistein and synthetic derivatives of isoflavone in cancer prevention and therapy. Mini Rev Med Chem. 2006;6:401-7 pubmed
Bairey Merz C, Johnson B, Braunstein G, Pepine C, Reis S, Paul Labrador M, et al. Phytoestrogens and lipoproteins in women. J Clin Endocrinol Metab. 2006;91:2209-13 pubmed
Dewell A, Hollenbeck P, Hollenbeck C. Clinical review: a critical evaluation of the role of soy protein and isoflavone supplementation in the control of plasma cholesterol concentrations. J Clin Endocrinol Metab. 2006;91:772-80 pubmed
Huang Y, Cao S, Nagamani M, Anderson K, Grady J, Lu L. Decreased circulating levels of tumor necrosis factor-alpha in postmenopausal women during consumption of soy-containing isoflavones. J Clin Endocrinol Metab. 2005;90:3956-62 pubmed
Bazuine M, van den Broek P, Maassen J. Genistein directly inhibits GLUT4-mediated glucose uptake in 3T3-L1 adipocytes. Biochem Biophys Res Commun. 2005;326:511-4 pubmed
Dijsselbloem N, Vanden Berghe W, De Naeyer A, Haegeman G. Soy isoflavone phyto-pharmaceuticals in interleukin-6 affections. Multi-purpose nutraceuticals at the crossroad of hormone replacement, anti-cancer and anti-inflammatory therapy. Biochem Pharmacol. 2004;68:1171-85 pubmed
Opałka M, Kaminska B, Ciereszko R, Dusza L. Genistein affects testosterone secretion by Leydig cells in roosters (Gallus gallus domesticus). Reprod Biol. 2004;4:185-93 pubmed
Sarkar F, Li Y. Mechanisms of cancer chemoprevention by soy isoflavone genistein. Cancer Metastasis Rev. 2002;21:265-80 pubmed
Lee D, Lee S. Genistein, a soy isoflavone, is a potent alpha-glucosidase inhibitor. FEBS Lett. 2001;501:84-6 pubmed
产品信息
产品编号 :
ALX-350-006
目录代码 :
ALX-350-006-G001
产品名称 :
Genistein (synthetic)
产品类型 :
Biochemical
规格 :
1 g
标价(美元) :
567美元
Pubmed号列表 :
25584415, 16613577, 16595605, 16384855, 15840745, 15582607, 15313415, 15297892, 12549765, 11457461
产品描述 :
Tyrosine protein kinase inhibitor. Inhibits phosphorylation of EGFR kinase. Inhibits tumor cell proliferation and induces tumor cell differentiation. Inhibits topoisomerase II activity in vivo. Produces cell cycle arrest and apoptosis. Potent inhibitor of α-glucosidase, IC50 = 50nM.Direct inhibitor of insulin-induced glucose uptake in adipocytes (IC50=20µM).
别名 :
4',5,7-Trihydroxyisoflavone
纯度 :
≥98%(HPLC)
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。