产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
化学品
产品名称 :
顺铂
目录 :
ALX-400-040-M250
规格 :
250毫克
更多信息或购买 :
文章摘录数: 12
参考文献 |
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Xiao L, Lu X, Ruden D. Effectiveness of hsp90 inhibitors as anti-cancer drugs. Mini Rev Med Chem. 2006;6:1137-43 pubmed
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van Waardenburg R, de Jong L, van Eijndhoven M, Verseyden C, Pluim D, Jansen L, et al. Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin. J Biol Chem. 2004;279:54502-9 pubmed
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Siddik Z. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene. 2003;22:7265-79 pubmed
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Bose R. Biomolecular targets for platinum antitumor drugs. Mini Rev Med Chem. 2002;2:103-11 pubmed
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Seki K, Yoshikawa H, Shiiki K, Hamada Y, Akamatsu N, Tasaka K. Cisplatin (CDDP) specifically induces apoptosis via sequential activation of caspase-8, -3 and -6 in osteosarcoma. Cancer Chemother Pharmacol. 2000;45:199-206 pubmed
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Razzaque M, Koji T, Kumatori A, Taguchi T. Cisplatin-induced apoptosis in human proximal tubular epithelial cells is associated with the activation of the Fas/Fas ligand system. Histochem Cell Biol. 1999;111:359-65 pubmed
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产品信息
产品编号 :
ALX-400-040
目录代码 :
ALX-400-040-M250
产品名称 :
顺铂
产品类型 :
Biochemical
规格 :
250毫克
Pubmed号列表 :
26213183, 25864590, 18628475, 18619662, 17073714, 15471886, 14576837, 12370072, 10663637, 10403114
产品描述 :
A potent platinum-based antineoplastic drug. Its mode of action involves formation of inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. Platinated DNA adducts also enhance poisoning of DNA topoisomerase I. Cisplatin synergizes with a variety of anticancer agents. Tumor cells rapidly develop resistance to cisplatin and numerous agents are available to block or reverse resistance.
别名 :
cis-Platinum(ll)diamine dichloride
纯度 :
≥98% (Assay)
储存 :
Ambient
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。