产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
蛋白
产品名称 :
TNF-α (soluble) (human), (recombinant)
目录 :
ALX-522-008-C050
规格 :
50微克
更多信息或购买 :
文章摘录数: 10
参考文献
de Almagro M, Goncharov T, Newton K, Vucic D. Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination. Cell Death Dis. 2015;6:e1800 pubmed 出版商
Song Y, Margolles Clark E, BAYER A, Buchwald P. Small-molecule modulators of the OX40-OX40 ligand co-stimulatory protein-protein interaction. Br J Pharmacol. 2014;171:4955-69 pubmed 出版商
Mahul Mellier A, Datler C, Pazarentzos E, Lin B, Chaisaklert W, Abuali G, et al. De-ubiquitinating proteases USP2a and USP2c cause apoptosis by stabilising RIP1. Biochim Biophys Acta. 2012;1823:1353-65 pubmed 出版商
Xue J, Thippegowda P, Hu G, Bachmaier K, Christman J, Malik A, et al. NF-kappaB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic NF-kappaB site in the ICAM-1 gene. Physiol Genomics. 2009;38:42-53 pubmed 出版商
Riol Blanco L, Sanchez Sanchez N, Torres A, Tejedor A, Narumiya S, Corbi A, et al. The chemokine receptor CCR7 activates in dendritic cells two signaling modules that independently regulate chemotaxis and migratory speed. J Immunol. 2005;174:4070-80 pubmed
Huard B, Arlettaz L, Ambrose C, Kindler V, Mauri D, Roosnek E, et al. BAFF production by antigen-presenting cells provides T cell co-stimulation. Int Immunol. 2004;16:467-75 pubmed
Micheau O, Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell. 2003;114:181-90 pubmed
Klunker S, Trautmann A, Akdis M, Verhagen J, Schmid Grendelmeier P, Blaser K, et al. A second step of chemotaxis after transendothelial migration: keratinocytes undergoing apoptosis release IFN-gamma-inducible protein 10, monokine induced by IFN-gamma, and IFN-gamma-inducible alpha-chemoattractant for T cell chemotaxis toward epiderm. J Immunol. 2003;171:1078-84 pubmed
Roehrich M, Mooser V, Lenain V, Herz J, Nimpf J, Azhar S, et al. Insulin-secreting beta-cell dysfunction induced by human lipoproteins. J Biol Chem. 2003;278:18368-75 pubmed
Schneider P, Holler N, Bodmer J, Hahne M, Frei K, Fontana A, et al. Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med. 1998;187:1205-13 pubmed
产品信息
产品编号 :
ALX-522-008
目录代码 :
ALX-522-008-C050
产品名称 :
TNF-α (soluble) (human), (recombinant)
产品类型 :
蛋白
规格 :
50微克
Pubmed号列表 :
26111062, 24930776, 22659130, 19351910, 15778365, 14978020, 12887920, 12847282, 12594227, 9547332
物种活性 :
人类, 小鼠
别名 :
Tumor necrosis factor-α, TNFSF 2
特异性 :
Binds to human and mouse TNF-R1 and less efficiently to TNF-R2. In the presence of cross-linking enhancer (Prod. No. ALX-804-034), TNF-α shows a significantly higher affinity for TNF-R2 than for TNF-R1, mimicking the characteristics of membrane-bound TNF-α.
纯度 :
≥95%(十二烷基磺酸钠-PAGE)
缓冲液 :
冻干。 含PBS
用途 :
ELISA: binds to TNF-R2 at 0.1-10 ng.
应用摘要 :
酶联免疫吸附测定
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。