产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
p糖蛋白(人类)单克隆抗体(C494)
目录 :
ALX-801-003-C100
规格 :
1毫升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
C494
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 15
出版应用/物种/样本/稀释 | 参考文献 |
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Poźniak B, Pawlak A, Obmińska Mrukowicz B. Flow cytometric assessment of P-glycoprotein and multidrug resistance-associated protein activity and expression in canine lymphoma. In Vivo. 2015;29:149-53 pubmed
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Schroeijers A, Reurs A, Scheffer G, Stam A, de Jong M, Rustemeyer T, et al. Up-regulation of drug resistance-related vaults during dendritic cell development. J Immunol. 2002;168:1572-8 pubmed
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Nuti S, Mehdi A, Rao U. Activation of the human P-glycoprotein ATPase by trypsin. Biochemistry. 2000;39:3424-32 pubmed
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Ng I, Liu C, Fan S, Ng M. Expression of P-glycoprotein in hepatocellular carcinoma. A determinant of chemotherapy response. Am J Clin Pathol. 2000;113:355-63 pubmed
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Wyman J, Hornstein A, Meitner P, Mak S, Verdier P, Block J, et al. Multidrug resistance-1 and p-glycoprotein in human chondrosarcoma cell lines: expression correlates with decreased intracellular doxorubicin and in vitro chemoresistance. J Orthop Res. 1999;17:935-40 pubmed
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Jimenez R, Zalupski M, Frank J, Du W, Ryan J, Lucas D. Multidrug resistance phenotype in high grade soft tissue sarcoma: correlation of P-glycoprotein immunohistochemistry with pathologic response to chemotherapy. Cancer. 1999;86:976-81 pubmed
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Rao V, Dahlheimer J, Bardgett M, Snyder A, Finch R, Sartorelli A, et al. Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier. Proc Natl Acad Sci U S A. 1999;96:3900-5 pubmed
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Lacueva F, Teruel A, Calpena R, Medrano J, Mayol M, Perez Vazquez M, et al. Detection of P-glycoprotein in frozen and paraffin-embedded gastric adenocarcinoma tissues using a panel of monoclonal antibodies. Histopathology. 1998;32:328-34 pubmed
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Rao V, Anthony D, Piwnica Worms D. MDR1 gene-specific monoclonal antibody C494 cross-reacts with pyruvate carboxylase. Cancer Res. 1994;54:1536-41 pubmed
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产品信息
产品编号 :
ALX-801-003
目录代码 :
ALX-801-003-C100
产品名称 :
p糖蛋白(人类)单克隆抗体(C494)
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
抗体
规格 :
1毫升
Pubmed号列表 :
25862123, 23786896, 11823484, 10727237, 10705815, 10632461, 10491523, 10097135, 9602329, 7511043
克隆 :
C494
抗体亚型 :
IgG2a
物种活性 :
人类
别名 :
ATP结合转运蛋白B超家族成员1, CD243, p糖蛋白1
免疫原 :
SDS-solubilized plasma membranes of an MDR (multidrug resistant) Chinese hamster ovary cell line and a human leukemic cell line.
特异性 :
Recognizes a gene-specific, internal cellular epitope present only on the human MDR1 isoform of P-glycoprotein.
缓冲液 :
液体。 在PBS含BSA和0.1% 叠氮化钠
用途 :
Flow Cytometry: cell permeabilization required. Immunocytochemistry: Cytospin preparations. Immunoprecipitation: The C494 MAb can be used to immunoprecipitate P-glycoprotein from lysates of metabolically or surface radiolabelled cells.
应用摘要 :
FC, 免疫细胞化学, 免疫组化(FS), 免疫组化(PS), 免疫沉淀, 免疫印迹
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。