产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
MRP2单克隆抗体(M2III-6)
目录 :
ALX-801-016-C250
规格 :
250微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
M2III-6
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
更多信息或购买 :
文章摘录数: 22
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 7a
Sayyed K, Vee M, Abdel Razzak Z, Jouan E, Stieger B, Denizot C, et al. Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate. Toxicology. 2016;363-364:58-71 pubmed 出版商
  • 免疫印迹; 人类
Bernd A, Ott M, Ishikawa H, Schroten H, Schwerk C, Fricker G. Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier. Pharm Res. 2015;32:2973-82 pubmed 出版商
  • 免疫印迹; 大鼠
Barosso I, Zucchetti A, Miszczuk G, Boaglio A, Taborda D, Roma M, et al. EGFR participates downstream of ERα in estradiol-17β-D-glucuronide-induced impairment of Abcc2 function in isolated rat hepatocyte couplets. Arch Toxicol. 2016;90:891-903 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Rigalli J, Ciriaci N, Arias A, Ceballos M, Villanueva S, Luquita M, et al. Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: impact on sorafenib cytotoxicity. PLoS ONE. 2015;10:e0119502 pubmed 出版商
  • 免疫印迹; 人类
Rigalli J, Perdomo V, Luquita M, Villanueva S, Arias A, Theile D, et al. Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptor. PLoS Negl Trop Dis. 2012;6:e1951 pubmed 出版商
  • 免疫细胞化学; 大鼠
  • 免疫印迹; 大鼠
Rosales R, Monte M, Blazquez A, Briz O, Marin J. ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds. Biochem Pharmacol. 2012;84:1651-9 pubmed 出版商
  • 免疫细胞化学; 大鼠
  • 免疫印迹; 大鼠
Tchaparian E, Houghton J, Uyeda C, Grillo M, Jin L. Effect of culture time on the basal expression levels of drug transporters in sandwich-cultured primary rat hepatocytes. Drug Metab Dispos. 2011;39:2387-94 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Haenisch S, Laechelt S, Bruckmueller H, Werk A, Noack A, Bruhn O, et al. Down-regulation of ATP-binding cassette C2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379. Mol Pharmacol. 2011;80:314-20 pubmed 出版商
Mayati A, Moreau A, Le Vee M, Bruyère A, Jouan E, Denizot C, et al. Functional polarization of human hepatoma HepaRG cells in response to forskolin. Sci Rep. 2018;8:16115 pubmed 出版商
Grammatikopoulos T, Sambrotta M, Strautnieks S, Foskett P, Knisely A, Wagner B, et al. Mutations in DCDC2 (doublecortin domain containing protein 2) in neonatal sclerosing cholangitis. J Hepatol. 2016;65:1179-1187 pubmed 出版商
Dröge C, Schaal H, Engelmann G, Wenning D, Haussinger D, Kubitz R. Exon-skipping and mRNA decay in human liver tissue: molecular consequences of pathogenic bile salt export pump mutations. Sci Rep. 2016;6:24827 pubmed 出版商
Striz A, Tuma P. The GTP-bound and Sumoylated Form of the rab17 Small Molecular Weight GTPase Selectively Binds Syntaxin 2 in Polarized Hepatic WIF-B Cells. J Biol Chem. 2016;291:9721-32 pubmed 出版商
Li H, Park G, Bae N, Kim J, Oh M, Yang H. Anti-apoptotic effect of modified Chunsimyeolda-tang, a traditional Korean herbal formula, on MPTP-induced neuronal cell death in a Parkinson's disease mouse model. J Ethnopharmacol. 2015;176:336-44 pubmed 出版商
Arana M, Tocchetti G, Domizi P, Arias A, Rigalli J, Ruiz M, et al. Coordinated induction of GST and MRP2 by cAMP in Caco-2 cells: Role of protein kinase A signaling pathway and toxicological relevance. Toxicol Appl Pharmacol. 2015;287:178-90 pubmed 出版商
Yang K, Pfeifer N, Hardwick R, Yue W, Stewart P, Brouwer K. An experimental approach to evaluate the impact of impaired transport function on hepatobiliary drug disposition using Mrp2-deficient TR- rat sandwich-cultured hepatocytes in combination with Bcrp knockdown. Mol Pharm. 2014;11:766-75 pubmed 出版商
Luna Tortós C, Fedrowitz M, Loscher W. Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy. Neuropharmacology. 2010;58:1019-32 pubmed 出版商
Honscha K, Schirmer A, Reischauer A, Schoon H, Einspanier A, Gabel G. Expression of ABC-transport proteins in canine mammary cancer: consequences for chemotherapy. Reprod Domest Anim. 2009;44 Suppl 2:218-23 pubmed 出版商
Lowes S, Simmons N. Multiple pathways for fluoroquinolone secretion by human intestinal epithelial (Caco-2) cells. Br J Pharmacol. 2002;135:1263-75 pubmed
Scheffer G, Kool M, Heijn M, de Haas M, Pijnenborg A, Wijnholds J, et al. Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies. Cancer Res. 2000;60:5269-77 pubmed
Hooijberg J, Broxterman H, Kool M, Assaraf Y, Peters G, Noordhuis P, et al. Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2. Cancer Res. 1999;59:2532-5 pubmed
Evers R, Kool M, van Deemter L, Janssen H, Calafat J, Oomen L, et al. Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA. J Clin Invest. 1998;101:1310-9 pubmed
Paulusma C, Bosma P, Zaman G, Bakker C, Otter M, Scheffer G, et al. Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Science. 1996;271:1126-8 pubmed
产品信息
产品编号 :
ALX-801-016
目录代码 :
ALX-801-016-C250
产品名称 :
MRP2单克隆抗体(M2III-6)
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
抗体
规格 :
250微克
Pubmed号列表 :
26593210, 26049102, 26049102, 20080116, 11877335, 11016657, 10363967, 9525973, 8599091
克隆 :
M2III-6
抗体亚型 :
IgG2a
物种活性 :
人类, 大鼠
别名 :
多药耐药相关蛋白2, cMOAT, ABCC2
免疫原 :
Recombinant C-terminal rat MRP2 (multidrug resistance-associated protein-2; cMOAT) (aa 1339-1541).
特异性 :
Recognizes an internal epitope of MRP2.
缓冲液 :
Liquid. In serum free culture supernatant containing 0.7% BSA and 0.1% sodium azide.
应用摘要 :
免疫细胞化学, 免疫组化(FS), 免疫组化(PS), 免疫印迹
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。