产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
CD51(人类)单克隆抗体(L230)
目录 :
ALX-803-304-C100
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
L230
反应物种 :
人类
应用 :
酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 8
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 图 s5a
Owen L, Adhikari A, Patel M, Grimmer P, Leijnse N, Kim M, et al. A cytoskeletal clutch mediates cellular force transmission in a soft, three-dimensional extracellular matrix. Mol Biol Cell. 2017;28:1959-1974 pubmed 出版商
Nevo J, Mai A, Tuomi S, Pellinen T, Pentikäinen O, Heikkila P, et al. Mammary-derived growth inhibitor (MDGI) interacts with integrin ?-subunits and suppresses integrin activity and invasion. Oncogene. 2010;29:6452-63 pubmed 出版商
Tuomi S, Mai A, Nevo J, Laine J, Vilkki V, Ohman T, et al. PKCepsilon regulation of an alpha5 integrin-ZO-1 complex controls lamellae formation in migrating cancer cells. Sci Signal. 2009;2:ra32 pubmed 出版商
Williams C, Kajander T, Hyypia T, Jackson T, Sheppard D, Stanway G. Integrin alpha v beta 6 is an RGD-dependent receptor for coxsackievirus A9. J Virol. 2004;78:6967-73 pubmed
Di Stefano P, Cabodi S, Boeri Erba E, Margaria V, Bergatto E, Giuffrida M, et al. P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading. Mol Biol Cell. 2004;15:787-800 pubmed
Moro L, Dolce L, Cabodi S, Bergatto E, Boeri Erba E, Smeriglio M, et al. Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines. J Biol Chem. 2002;277:9405-14 pubmed
Schwartz B, Karsan A, Bombeli T, Harlan J. A novel beta 1 integrin-dependent mechanism of leukocyte adherence to apoptotic cells. J Immunol. 1999;162:4842-8 pubmed
Weinacker A, Chen A, Agrez M, Cone R, Nishimura S, Wayner E, et al. Role of the integrin alpha v beta 6 in cell attachment to fibronectin. Heterologous expression of intact and secreted forms of the receptor. J Biol Chem. 1994;269:6940-8 pubmed
产品信息
产品编号 :
ALX-803-304
目录代码 :
ALX-803-304-C100
产品名称 :
CD51(人类)单克隆抗体(L230)
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
抗体
规格 :
100微克
Pubmed号列表 :
20802519, 19567915, 15194773, 14657239, 11756413, 10202028, 8120056
克隆 :
L230
抗体亚型 :
IgG1
物种活性 :
人类
背景 :
CD51 (integrin αV subunit) associates with CD61 (integrin β3 subunit) binding to the RGD sequence in extracellular matrix proteins like vitronectin, fibrinogen, thrombospondin, von Willebrand factor and osteopontin. The αV/β3 heterodimer is expressed in endothelial cells, leukocytes, NK cells, macrophages, neutrophils, platelets and several malignant tumor cells and seems to play a role in embryo implantation, angiogenesis, wound healing and cancer. αV/β3  is also highly expressed in osteoclasts being important for bone resorption.
别名 :
αV integrin, Vitronectin receptor α subunit
免疫原 :
人类内皮细胞
特异性 :
Recognizes heterodimers αVβ3, αVβ1, αVβ5 and αVβ6.
缓冲液 :
液体。 在PBS含0.05% 叠氮化钠
用途 :
Functional Application: αV integrin blocking
应用摘要 :
酶联免疫吸附测定, FC, IF, 免疫组化, 免疫沉淀, FUNC
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。