产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
TRAIL-R1(人类)单克隆抗体(HS101)(异硫氰酸荧光素共轭标签)
目录 :
ALX-804-297F-T100
规格 :
100试验
价格 :
443美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
HS101
反应物种 :
人类
应用 :
免疫细胞化学, 流式细胞仪
更多信息或购买 :
文章摘录数: 11
出版应用/物种/样品/稀释参考文献
  • 流式细胞仪; 人类; 图 4
De Toni E, Ziesch A, Rizzani A, Török H, Hocke S, Lü S, et al. Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis. Oncotarget. 2016;7:9477-90 pubmed 出版商
Mucha S, Rizzani A, Gerbes A, Camaj P, Thasler W, Bruns C, et al. JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand. Gut. 2009;58:688-98 pubmed 出版商
Contassot E, Kerl K, Roques S, Shane R, Gaide O, Dupuis M, et al. Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sezary syndrome T-cells associated with impaired death receptor and FLICE-inhibitory protein expression. Blood. 2008;111:4780-7 pubmed 出版商
De Toni E, Kuntzen C, Gerbes A, Thasler W, Sonuc N, Mucha S, et al. P60-c-src suppresses apoptosis through inhibition of caspase 8 activation in hepatoma cells, but not in primary hepatocytes. J Hepatol. 2007;46:682-91 pubmed
Izeradjene K, Douglas L, Delaney A, Houghton J. Casein kinase I attenuates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by regulating the recruitment of fas-associated death domain and procaspase-8 to the death-inducing signaling complex. Cancer Res. 2004;64:8036-44 pubmed
Wachter T, Sprick M, Hausmann D, Kerstan A, McPherson K, Stassi G, et al. cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes. J Biol Chem. 2004;279:52824-34 pubmed
Ganten T, Haas T, Sykora J, Stahl H, Sprick M, Fas S, et al. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs. Cell Death Differ. 2004;11 Suppl 1:S86-96 pubmed
Tecchio C, Huber V, Scapini P, Calzetti F, Margotto D, Todeschini G, et al. IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells. Blood. 2004;103:3837-44 pubmed
Secchiero P, Melloni E, Heikinheimo M, Mannisto S, Di Pietro R, Iacone A, et al. TRAIL regulates normal erythroid maturation through an ERK-dependent pathway. Blood. 2004;103:517-22 pubmed
Hopkins Donaldson S, Ziegler A, Kurtz S, Bigosch C, Kandioler D, Ludwig C, et al. Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation. Cell Death Differ. 2003;10:356-64 pubmed
Washburn B, Weigand M, Grosse Wilde A, Janke M, Stahl H, Rieser E, et al. TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus. J Immunol. 2003;170:1814-21 pubmed
产品信息
产品编号 :
ALX-804-297F
目录代码 :
ALX-804-297F-T100
产品名称 :
TRAIL-R1(人类)单克隆抗体(HS101)(异硫氰酸荧光素共轭标签)
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
异硫氰酸荧光素
产品类型 :
抗体
规格 :
100试验
标价(美元) :
443美元
Pubmed号列表 :
19106147, 18314443, 17224200, 15520213, 15459191, 15105837, 14726404, 12969966, 12700635, 12574346
克隆 :
HS101
抗体亚型 :
IgG1
物种活性 :
人类
别名 :
TRAIL receptor 1, Apo-2, CD261, DR4, Death receptor 4, TNFRSF 10A, TNF-related apoptosis-inducing ligand receptor 1, Tumor necrosis factor receptor superfamily member 10A
免疫原 :
重组人类TRAIL-R1
缓冲液 :
Liquid. 50µg in PBS containing 0.09% sodium azide.
应用摘要 :
FC, 免疫细胞化学
储存 :
+4°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。