产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
Fas (human) monoclonal antibody (APO-1-3)
目录 :
ALX-805-020-C100
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
ApoE基因-1
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 15
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 2f
Marozin S, Altomonte J, Muñoz Álvarez K, Rizzani A, De Toni E, Thasler W, et al. STAT3 inhibition reduces toxicity of oncolytic VSV and provides a potentially synergistic combination therapy for hepatocellular carcinoma. Cancer Gene Ther. 2015;22:317-25 pubmed 出版商
Durrieu L, Dieng M, Le Deist F, Haddad E. Cord blood-derived and peripheral blood-derived cytokine-induced killer cells are sensitive to Fas-mediated apoptosis. Biol Blood Marrow Transplant. 2013;19:1407-11 pubmed 出版商
Kuehn H, Niemela J, Rangel Santos A, Zhang M, Pittaluga S, Stoddard J, et al. Loss-of-function of the protein kinase C ? (PKC?) causes a B-cell lymphoproliferative syndrome in humans. Blood. 2013;121:3117-25 pubmed 出版商
Lo B, Ramaswamy M, Davis J, Price S, Rao V, Siegel R, et al. A rapid ex vivo clinical diagnostic assay for fas receptor-induced T lymphocyte apoptosis. J Clin Immunol. 2013;33:479-88 pubmed 出版商
Kuehn H, Caminha I, Niemela J, Rao V, Davis J, Fleisher T, et al. FAS haploinsufficiency is a common disease mechanism in the human autoimmune lymphoproliferative syndrome. J Immunol. 2011;186:6035-43 pubmed 出版商
Ramaswamy M, Cruz A, Cleland S, Deng M, Price S, Rao V, et al. Specific elimination of effector memory CD4+ T cells due to enhanced Fas signaling complex formation and association with lipid raft microdomains. Cell Death Differ. 2011;18:712-20 pubmed 出版商
Chu P, Deforce D, Pedersen I, Kim Y, Kitada S, Reed J, et al. Latent sensitivity to Fas-mediated apoptosis after CD40 ligation may explain activity of CD154 gene therapy in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2002;99:3854-9 pubmed
Osborne B. Apoptosis and the maintenance of homoeostasis in the immune system. Curr Opin Immunol. 1996;8:245-54 pubmed
Friesen C, Herr I, Krammer P, Debatin K. Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med. 1996;2:574-7 pubmed
Kischkel F, Hellbardt S, Behrmann I, Germer M, Pawlita M, Krammer P, et al. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 1995;14:5579-88 pubmed
Debatin K, Goldman C, Waldmann T, Krammer P. APO-1-induced apoptosis of leukemia cells from patients with adult T-cell leukemia. Blood. 1993;81:2972-7 pubmed
Schattner E, Elkon K, Yoo D, Tumang J, Krammer P, Crow M, et al. CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway. J Exp Med. 1995;182:1557-65 pubmed
Westendorp M, Frank R, Ochsenbauer C, Stricker K, Dhein J, Walczak H, et al. Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature. 1995;375:497-500 pubmed
Debatin K, Krammer P. Resistance to APO-1 (CD95) induced apoptosis in T-ALL is determined by a BCL-2 independent anti-apoptotic program. Leukemia. 1995;9:815-20 pubmed
Copeland K, Haaksma A, Goudsmit J, Krammer P, Heeney J. Inhibition of apoptosis in T cells expressing human T cell leukemia virus type I Tax. AIDS Res Hum Retroviruses. 1994;10:1259-68 pubmed
产品信息
产品编号 :
ALX-805-020
目录代码 :
ALX-805-020-C100
产品名称 :
Fas (human) monoclonal antibody (APO-1-3)
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
抗体
规格 :
100微克
Pubmed号列表 :
25930184, 11891278, 8725948, 8616718, 8521815, 7684622, 7595225, 7539892, 7539514, 7531462
克隆 :
ApoE基因-1
抗体亚型 :
IgG3
物种活性 :
人类
别名 :
CD95, ApoE基因-1, TNFRSF 6
免疫原 :
Human recombinant Fas (CD95; APO-1).
缓冲液 :
液体。 在PBS。 含无防腐剂
用途 :
Functional Application: induces apoptosis with or without cross-linking (Protein A), depending on cell type.
应用摘要 :
FC, 免疫沉淀, 免疫印迹, FUNC
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。