产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
Fas (human) monoclonal antibody (APO-1-1)
目录 :
ALX-805-022-C100
规格 :
100微克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
ApoE基因-1
反应物种 :
人类
应用 :
免疫组化, 流式细胞仪
更多信息或购买 :
Enzo Life Sciences 产品网页
文章摘录数: 6
参考文献
Backes C, Friedmann K, Mang S, Knörck A, Hoth M, Kummerow C. Natural killer cells induce distinct modes of cancer cell death: Discrimination, quantification, and modulation of apoptosis, necrosis, and mixed forms. J Biol Chem. 2018;293:16348-16363 pubmed 出版商
Salva K, Kim Y, Rahbar Z, Wood G. Epigenetically Enhanced PDT Induces Significantly Higher Levels of Multiple Extrinsic Pathway Apoptotic Factors than Standard PDT, Resulting in Greater Extrinsic and Overall Apoptosis of Cutaneous T-cell Lymphoma. Photochem Photobiol. 2018;94:1058-1065 pubmed 出版商
Ramaswamy M, Cruz A, Cleland S, Deng M, Price S, Rao V, et al. Specific elimination of effector memory CD4+ T cells due to enhanced Fas signaling complex formation and association with lipid raft microdomains. Cell Death Differ. 2011;18:712-20 pubmed 出版商
Wajant H, Haas E, Schwenzer R, Muhlenbeck F, Kreuz S, Schubert G, et al. Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD). J Biol Chem. 2000;275:24357-66 pubmed
Huang D, Hahne M, Schroeter M, Frei K, Fontana A, Villunger A, et al. Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L). Proc Natl Acad Sci U S A. 1999;96:14871-6 pubmed
Leithäuser F, Dhein J, Mechtersheimer G, Koretz K, Bruderlein S, Henne C, et al. Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells. Lab Invest. 1993;69:415-29 pubmed
产品信息
产品编号 :
ALX-805-022
目录代码 :
ALX-805-022-C100
产品名称 :
Fas (human) monoclonal antibody (APO-1-1)
宿主物种 :
小鼠
克隆性 :
单克隆
产品类型 :
抗体
规格 :
100微克
Pubmed号列表 :
10823821, 10611305, 7693996
克隆 :
ApoE基因-1
抗体亚型 :
IgG1
物种活性 :
人类
别名 :
CD95, ApoE基因-1, TNFRSF 6
免疫原 :
Human Fas (CD95; APO-1).
缓冲液 :
液体。 在PBS, pH值7.2-7.4
用途 :
APO-1-1 (IgG1) is an isotype-switch variant of the original clone APO-1-3 (ALX-805-020). Since undesired side reactions in immunohistochemistry are minimal for IgG1 antibodies, APO-1-1 is especially useful for immunohistology on cryostat sections and on cytospin preparations. Not suitable for stainings on paraffin sections. Functional Application: Induces apoptosis upon cross-linking.
应用摘要 :
FC, 免疫组化(FS), FUNC
储存 :
+4°C
更多信息或购买 :
Enzo Life Sciences 产品网页
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。