产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
CD40(小鼠)单克隆抗体(FGK45)(生物素共轭标签)
目录 :
ALX-805-046B-C050
规格 :
50微克
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
生物素
克隆名称 :
FGK45
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
Enzo Life Sciences 产品网页
文章摘录数: 13
参考文献
Lee Chang C, Bodogai M, Moritoh K, Chen X, Wersto R, Sen R, et al. Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers. J Immunol. 2016;196:3385-97 pubmed 出版商
Zanotti K, Maul R, Castiblanco D, Yang W, Choi Y, Fox J, et al. ATAD5 deficiency decreases B cell division and Igh recombination. J Immunol. 2015;194:35-42 pubmed 出版商
Coffey F, Manser T. Expression of cellular FLIP by B cells is required for their participation in an immune response. J Immunol. 2010;184:4871-9 pubmed 出版商
Bartholdy C, Kauffmann S, Christensen J, Thomsen A. Agonistic anti-CD40 antibody profoundly suppresses the immune response to infection with lymphocytic choriomeningitis virus. J Immunol. 2007;178:1662-70 pubmed
Hellings P, Kasran A, Bullens D, Overbergh L, Mathieu C, Heremans H, et al. IL-10- and IL-12-independent down-regulation of allergic sensitization by stimulation of CD40 signaling. J Immunol. 2006;177:5138-44 pubmed
Greene J, DeVecchio J, Gould M, Auletta J, Heinzel F. In vivo and in vitro regulation of type I IFN synthesis by synergistic effects of CD40 and type II IFN. J Immunol. 2006;176:5995-6003 pubmed
Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature. 2005;434:772-7 pubmed
Erlebacher A, Zhang D, Parlow A, Glimcher L. Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system. J Clin Invest. 2004;114:39-48 pubmed
McGregor C, Schoenberger S, Green E. CD154 is a negative regulator of autoaggressive CD8+ T cells in type 1 diabetes. Proc Natl Acad Sci U S A. 2004;101:9345-50 pubmed
Turner J, Rakhmilevich A, Burdelya L, Neal Z, Imboden M, Sondel P, et al. Anti-CD40 antibody induces antitumor and antimetastatic effects: the role of NK cells. J Immunol. 2001;166:89-94 pubmed
Mauri C, Mars L, Londei M. Therapeutic activity of agonistic monoclonal antibodies against CD40 in a chronic autoimmune inflammatory process. Nat Med. 2000;6:673-9 pubmed
Rolink A, Andersson J, Melchers F. Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity. Eur J Immunol. 1998;28:3738-48 pubmed
Rolink A, Melchers F, Andersson J. The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching. Immunity. 1996;5:319-30 pubmed
产品信息
产品编号 :
ALX-805-046B
目录代码 :
ALX-805-046B-C050
产品名称 :
CD40(小鼠)单克隆抗体(FGK45)(生物素共轭标签)
宿主物种 :
大鼠
克隆性 :
单克隆
共轭 :
生物素
产品类型 :
抗体
规格 :
50微克
Pubmed号列表 :
17237416, 17015698, 16670308, 15800576, 15232610, 15192149, 11123280, 10835684, 9842916, 8885865
克隆 :
FGK45
抗体亚型 :
IgG2a
产品描述 :
Widely used stimulatory MAb to CD40. Shown to indirectly activate natural killer (NK) cells, producing significant antitumor and antimetastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes.
物种活性 :
小鼠
别名 :
TNFRSF 5
免疫原 :
重组小鼠CD40融合蛋白
缓冲液 :
Liquid. In sterile PBS.
应用摘要 :
FC
储存 :
+4°C
更多信息或购买 :
Enzo Life Sciences 产品网页
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。