产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
抗体
产品名称 :
CD40 (mouse) monoclonal antibody (FGK45) (preservative free)
目录 :
ALX-805-046PF-C100
规格 :
100微克
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
FGK45
反应物种 :
小鼠
应用 :
免疫细胞化学, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 13
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 小鼠; 0.5 ug/ml
Zanotti K, Maul R, Castiblanco D, Yang W, Choi Y, Fox J, et al. ATAD5 deficiency decreases B cell division and Igh recombination. J Immunol. 2015;194:35-42 pubmed 出版商
  • 免疫细胞化学; 小鼠
Coffey F, Manser T. Expression of cellular FLIP by B cells is required for their participation in an immune response. J Immunol. 2010;184:4871-9 pubmed 出版商
Avery D, Kane A, Nguyen T, Lau A, Nguyen A, Lenthall H, et al. Germline-activating mutations in PIK3CD compromise B cell development and function. J Exp Med. 2018;215:2073-2095 pubmed 出版商
Goldman N, Valiuskyte K, Londregan J, Swider A, Somerville J, Riggs J. Macrophage regulation of B cell proliferation. Cell Immunol. 2017;314:54-62 pubmed 出版商
Lee Chang C, Bodogai M, Moritoh K, Chen X, Wersto R, Sen R, et al. Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers. J Immunol. 2016;196:3385-97 pubmed 出版商
Shigeta A, Tada Y, Wang J, Ishizaki S, Tsuyusaki J, Yamauchi K, et al. CD40 amplifies Fas-mediated apoptosis: a mechanism contributing to emphysema. Am J Physiol Lung Cell Mol Physiol. 2012;303:L141-51 pubmed 出版商
Fear V, Burchell J, Lai S, Wikstrom M, Blank F, von Garnier C, et al. Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specific CD4+ T cell proliferation during the induction of inhalation tolerance. J Immunol. 2011;187:4561-70 pubmed 出版商
Yanai H, Chiba S, Ban T, Nakaima Y, Onoe T, Honda K, et al. Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs). Proc Natl Acad Sci U S A. 2011;108:11542-7 pubmed 出版商
Carlucci F, Fossati Jimack L, Dumitriu I, Heidari Y, Walport M, Szajna M, et al. Identification and characterization of a lupus suppressor 129 locus on chromosome 3. J Immunol. 2010;184:6256-65 pubmed 出版商
Schroder W, Le T, Major L, Street S, Gardner J, Lambley E, et al. A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity. J Immunol. 2010;184:2663-70 pubmed 出版商
Zhang T, Al Alwan M, Marshall A. The pleckstrin homology domain adaptor protein Bam32/DAPP1 is required for germinal center progression. J Immunol. 2010;184:164-72 pubmed 出版商
Zhang H, Rosenberg S, Coffey F, He Y, Manser T, Hardy R, et al. A role for cFLIP in B cell proliferation and stress MAPK regulation. J Immunol. 2009;182:207-15 pubmed
Bartholdy C, Kauffmann S, Christensen J, Thomsen A. Agonistic anti-CD40 antibody profoundly suppresses the immune response to infection with lymphocytic choriomeningitis virus. J Immunol. 2007;178:1662-70 pubmed
产品信息
产品编号 :
ALX-805-046PF
目录代码 :
ALX-805-046PF-C100
产品名称 :
CD40 (mouse) monoclonal antibody (FGK45) (preservative free)
宿主物种 :
大鼠
克隆性 :
单克隆
产品类型 :
抗体
规格 :
100微克
Pubmed号列表 :
25404367, 22610351, 21930961, 21709231, 20435933, 20335528, 20130210, 19949096, 19109151, 17237416
克隆 :
FGK45
抗体亚型 :
IgG2a
产品描述 :
Widely used stimulatory MAb to CD40. Shown to indirectly activate natural killer (NK) cells, producing significant antitumor and antimetastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes.
物种活性 :
小鼠
别名 :
TNFRSF 5
免疫原 :
重组小鼠CD40融合蛋白
缓冲液 :
Liquid. In sterile PBS.
用途 :
Functional Application: activates B and NK cells in vivo and in vitro.
应用摘要 :
FC, FUNC
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。