Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

ELISA/assay

脂联素(人类), 酶联免疫吸附试剂盒

ALX-850-377-KI01

96 wells

ALX-850-377-KI01

脂联素(人类), 酶联免疫吸附试剂盒

Kit

96 wells

24489777

The Adiponectin (human), ELISA kit is a colorimetric, immunometric immunoassay kit with results in <3 hours.

人类

Adiponectin, also referred to as Acrp30, AdipoQ and GBP-28, is a 244 amino acid protein, the product of the apM1 gene, which is physiologically active and specifically and highly expressed in adipose cells. The protein belongs to the soluble defence collagen superfamily; it has a collagen-like domain structurally homologous with collagen VIII and X and complement factor C1q-like globular domain. Adiponectin forms homotrimers, which are the building blocks for higher order complexes found circulating in serum. Together, these complexes make up approximately 0.01% of total serum protein. Adiponectin receptors AdipoR1 and AdipoR2 have been recently cloned; AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. Paradoxically, adipose tissue-expressed adiponectin levels are inversely related to the degree of adiposity. Adiponectin concentrations correlate negatively with glucose, insulin, triglyceride concentrations, liver fat content and body mass index and positively with high-density lipoprotein-cholesterol levels, hepatic insulin sensitivity and insulin-stimulated glucose disposal. Adiponectin has been shown to increase insulin sensitivity and decrease plasma glucose by increasing tissue fat oxidation.

ACRP30, ADIPOQ, GBP28, Adipocyte C1q and collagen domain-containing protein, Adipocyte complement-related 30 kDa protein, Gelatin-binding protein, ACDC, APM1

For quantitative determination of human adiponectin in cerebrospinal fluid, plasma, serum, urine and (breast) milk.

ELISA, Colorimetric detection

+4°C