产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
化学品
产品名称 :
硫酸博莱霉素
目录 :
BML-AP302-0050
规格 :
50毫克
更多信息或购买 :
Enzo Life Sciences 产品网页
文章摘录数: 11
参考文献
Shaghaghi H, Cuevas Mora K, Para R, Tran C, Roque W, Robertson M, et al. A model of the aged lung epithelium in idiopathic pulmonary fibrosis. Aging (Albany NY). 2021;13:16922-16937 pubmed 出版商
Shah D, Romero F, Stafstrom W, Duong M, Summer R. Extracellular ATP mediates the late phase of neutrophil recruitment to the lung in murine models of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2014;306:L152-61 pubmed 出版商
Kullberg M, Mann K, Anchordoquy T. Targeting Her-2+ breast cancer cells with bleomycin immunoliposomes linked to LLO. Mol Pharm. 2012;9:2000-8 pubmed 出版商
Dziegielewski J, Melendy T, Beerman T. Bleomycin-induced alterations in DNA replication: relationship to DNA damage. Biochemistry. 2001;40:704-11 pubmed
Hecht S. Bleomycin: new perspectives on the mechanism of action. J Nat Prod. 2000;63:158-68 pubmed
Muller M, Wilder S, Bannasch D, Israeli D, Lehlbach K, Li Weber M, et al. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med. 1998;188:2033-45 pubmed
Christensen J, Gonzales A, Cattley R, Goldsworthy T. Regulation of apoptosis in mouse hepatocytes and alteration of apoptosis by nongenotoxic carcinogens. Cell Growth Differ. 1998;9:815-25 pubmed
Vernole P, Tedeschi B, Caporossi D, Maccarrone M, Melino G, Annicchiarico Petruzzelli M. Induction of apoptosis by bleomycin in resting and cycling human lymphocytes. Mutagenesis. 1998;13:209-15 pubmed
Sam J, Takahashi S, Lippai I, Peisach J, Rousseau D. Sequence-specific changes in the metal site of ferric bleomycin induced by the binding of DNA. J Biol Chem. 1998;273:16090-7 pubmed
Araki T, Enokido Y, Inamura N, Aizawa S, Reed J, Hatanaka H. Changes in c-Jun but not Bcl-2 family proteins in p53-dependent apoptosis of mouse cerebellar granule neurons induced by DNA damaging agent bleomycin. Brain Res. 1998;794:239-47 pubmed
Schirner M, Hoffmann J, Menrad A, Schneider M. Antiangiogenic chemotherapeutic agents: characterization in comparison to their tumor growth inhibition in human renal cell carcinoma models. Clin Cancer Res. 1998;4:1331-6 pubmed
产品信息
产品编号 :
BML-AP302
目录代码 :
BML-AP302-0050
产品名称 :
硫酸博莱霉素
产品类型 :
Biochemical
规格 :
50毫克
Pubmed号列表 :
24285266, 22621404, 11170387, 10650103, 9841917, 9751125, 9643578, 9632661, 9622642, 9607594
产品描述 :
Anti-tumor agent. Induces apoptosis via DNA damage. Radiomimetic DNA-cleaving agent that produces double and single DNA strand breaks through an oxygen-radical-dependent mechanism. Inhibits intracellular DNA replication. DNA alkylating agent.
别名 :
硫酸博来霉素<抗肿瘤抗生素>
纯度 :
≥98%(HPLC)
储存 :
-20°C
更多信息或购买 :
Enzo Life Sciences 产品网页
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。