产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
化学品
产品名称 :
愈创木酸
目录 :
BML-EI101-0001
规格 :
1 g
更多信息或购买 :
文章摘录数: 10
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Siddique Y, Ara G, Beg T, Afzal M. Protective role of nordihydroguaiaretic acid (NDGA) against the genotoxic damage induced by ethynodiol diacetate in human lymphocytes in vitro. J Environ Biol. 2007;28:279-82 pubmed
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Arasaki K, Tani K, Yoshimori T, Stephens D, Tagaya M. Nordihydroguaiaretic acid affects multiple dynein-dynactin functions in interphase and mitotic cells. Mol Pharmacol. 2007;71:454-60 pubmed
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Floriano Sánchez E, Villanueva C, Medina Campos O, Rocha D, Sánchez González D, Cárdenas Rodríguez N, et al. Nordihydroguaiaretic acid is a potent in vitro scavenger of peroxynitrite, singlet oxygen, hydroxyl radical, superoxide anion and hypochlorous acid and prevents in vivo ozone-induced tyrosine nitration in lungs. Free Radic Res. 2006;40:523-33 pubmed
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Culver C, Michalowski S, Maia R, Laster S. The anti-apoptotic effects of nordihydroguaiaretic acid: inhibition of cPLA(2) activation during TNF-induced apoptosis arises from inhibition of calcium signaling. Life Sci. 2005;77:2457-70 pubmed
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Fischer R, Köhler K, Fotin Mleczek M, Brock R. A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides. J Biol Chem. 2004;279:12625-35 pubmed
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Fujiwara T, Misumi Y, Ikehara Y. Direct interaction of the Golgi membrane with the endoplasmic reticulum membrane caused by nordihydroguaiaretic acid. Biochem Biophys Res Commun. 2003;301:927-33 pubmed
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Kim S, Park T, Park J. Effect of nordihydroguaiaretic acid on the secretion of lipoprotein lipase. J Biochem Mol Biol. 2002;35:518-23 pubmed
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Yamamura H, Sakamoto K, Ohya S, Muraki K, Imaizumi Y. Mechanisms underlying the activation of large conductance Ca2+-activated K+ channels by nordihydroguaiaretic acid. Jpn J Pharmacol. 2002;89:53-63 pubmed
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Fujiwara T, Takami N, Misumi Y, Ikehara Y. Nordihydroguaiaretic acid blocks protein transport in the secretory pathway causing redistribution of Golgi proteins into the endoplasmic reticulum. J Biol Chem. 1998;273:3068-75 pubmed
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Pavani M, Fones E, Oksenberg D, Garcia M, Hernandez C, Cordano G, et al. Inhibition of tumoral cell respiration and growth by nordihydroguaiaretic acid. Biochem Pharmacol. 1994;48:1935-42 pubmed
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产品信息
产品编号 :
BML-EI101
目录代码 :
BML-EI101-0001
产品名称 :
愈创木酸
产品类型 :
Biochemical
规格 :
1 g
Pubmed号列表 :
17915765, 17105871, 16551579, 15950244, 14707144, 12589801, 12359096, 12083743, 9446623, 7986205
产品描述 :
Antioxidant and antineoplastic. Lipoxygenase inhibitor (IC50=0.2, 30 and 30µM for 5-, 12- and 15-LO respectively) over cyclooxygenase (IC50=100µM). Inhibits rat epidermal and hepatic microsomal cytochrome P-450 (ID50=40µM). Stimulates the rapid retrograde movement of both Golgi stacks and the trans-Golgi network to the endoplasmatic reticulum (ER). Displays pleiotropic effects on cells, which include apoptosis, cell proliferation, differentiation and chemotaxis. Anticancer agent.
别名 :
NDGA, 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis[1,2-benzenediol]
纯度 :
≥97%(HPLC)
储存 :
Ambient
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com1-800-942-0430
公司总部: 美国
自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。