Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

抗体

纤连蛋白(血浆)(人类)单克隆抗体(BF12)

BML-FG6020-0100

100微升

单克隆

小鼠

未共轭

BF12

免疫印迹, 免疫细胞化学

BML-FG6020-0100

纤连蛋白(血浆)(人类)单克隆抗体(BF12)

小鼠

单克隆

抗体

100微升

BF12

IgG1

人类

Fibronectins are high molecular weight, disulphide-linked, dimeric cell adhesion glycoproteins found in basement membranes and in the interstitial connective tissue matrix. A single fibronectin gene is subject to alternative splicing in a cell-type-, development- and age-regulated manner which gives rise to multiple molecular forms. In addition to their prominent role in adhesion, fibronectins have been reported to mediate various aspects of cellular interaction, including migration during development and wound-healing, haemostasis, and the regulation of cell growth and differentiation. Cellular fibronectins (cFn) are found in low amounts in normal human plasma and tissues, but they are abundant in the plasma of carcinoma patients and in the stroma of various carcinomas. In contrast, a soluble form of fibronectin produced by hepatocytes is readily detectable in plasma and becomes deposited in pericellular matrices and within tissues. This form of fibronectin, referred to as ‘plasma fibronectin’ (pFn), differs from cFn by the absence of an amino acid sequence, known as extra domain A1.

pFn

纯化纤连蛋白来自A8387纤维肉瘤细胞

Recognizes the cell binding region of fibronectin.

液体。 在PBS含0.1% 叠氮化钠和1毫克/毫升BSA

Detects a band of ~225-250kDa by Western blot.

免疫细胞化学, 免疫印迹

-20°C