产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
化学品
产品名称 :
褪黑素
目录 :
BML-NS520-0001
规格 :
1 g
更多信息或购买 :
文章摘录数: 10
| 参考文献 |
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Tamura E, Silva C, Markus R. Melatonin inhibits endothelial nitric oxide production in vitro. J Pineal Res. 2006;41:267-74 pubmed
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Aydogan S, Yerer M, Goktas A. Melatonin and nitric oxide. J Endocrinol Invest. 2006;29:281-7 pubmed
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Deng W, Tang S, Tseng H, Wu K. Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding. Blood. 2006;108:518-24 pubmed
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Acuna Castroviejo D, Escames G, Leon J, Carazo A, Khaldy H. Mitochondrial regulation by melatonin and its metabolites. Adv Exp Med Biol. 2003;527:549-57 pubmed
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Andrabi S, Sayeed I, Siemen D, Wolf G, Horn T. Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti-apoptotic effects of melatonin. FASEB J. 2004;18:869-71 pubmed
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Dobsak P, Siegelova J, Eicher J, Jancik J, Svacinová H, Vasku J, et al. Melatonin protects against ischemia-reperfusion injury and inhibits apoptosis in isolated working rat heart. Pathophysiology. 2003;9:179-187 pubmed
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Matsubara E, Bryant Thomas T, Pacheco Quinto J, Henry T, Poeggeler B, Herbert D, et al. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease. J Neurochem. 2003;85:1101-8 pubmed
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Yoo Y, Yim S, Kim S, Jang H, Lea H, Hwang G, et al. Melatonin suppresses NO-induced apoptosis via induction of Bcl-2 expression in PGT-beta immortalized pineal cells. J Pineal Res. 2002;33:146-50 pubmed
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Blanchard B, Pompon D, Ducrocq C. Nitrosation of melatonin by nitric oxide and peroxynitrite. J Pineal Res. 2000;29:184-92 pubmed
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Lahiri D, Ghosh C. Interactions between melatonin, reactive oxygen species, and nitric oxide. Ann N Y Acad Sci. 1999;893:325-30 pubmed
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产品信息
产品编号 :
BML-NS520
目录代码 :
BML-NS520-0001
产品名称 :
褪黑素
产品类型 :
Biochemical
规格 :
1 g
Pubmed号列表 :
16948788, 16682846, 16609073, 15206773, 15033929, 14567933, 12753069, 12220328, 11034116, 10672259
产品描述 :
Endogenous agonist at melatonin MT1 and MT2 receptors. Displays antioxidant and antiapoptotic effects in numerous cell types as well as beneficial effects in various neurodegenerative diseases. It protects neuronal cells from amyloid beta-mediated oxidative damage and increases survival in an Alzheimer’s disease transgenic mouse model. Melatonin directly inhibits mitochondrial permeability transition pore (IC50 = 0.8M) and reduced the loss of neurons in a rat model of transient brain ischemia.
别名 :
N乙酰
纯度 :
≥98%(HPLC)
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com1-800-942-0430
公司总部: 美国
自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。