产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
蛋白
产品名称 :
NF-κB SN50M cell permeable control peptide
目录 :
BML-P601-0500
规格 :
0.5毫克
更多信息或购买 :
文章摘录数: 4
参考文献
Tomasello D, Gancarz Kausch A, Dietz D, Bhattacharjee A. Transcriptional Regulation of the Sodium-activated Potassium Channel SLICK (KCNT2) Promoter by Nuclear Factor-κB. J Biol Chem. 2015;290:18575-83 pubmed 出版商
Moriwaki K, Shinzaki S, Miyoshi E. GDP-mannose-4,6-dehydratase (GMDS) deficiency renders colon cancer cells resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor- and CD95-mediated apoptosis by inhibiting complex II formation. J Biol Chem. 2011;286:43123-33 pubmed 出版商
Dai Y, Pei X, Rahmani M, Conrad D, Dent P, Grant S. Interruption of the NF-kappaB pathway by Bay 11-7082 promotes UCN-01-mediated mitochondrial dysfunction and apoptosis in human multiple myeloma cells. Blood. 2004;103:2761-70 pubmed
Lin Y, Yao S, Veach R, Torgerson T, Hawiger J. Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J Biol Chem. 1995;270:14255-8 pubmed
产品信息
产品编号 :
BML-P601
目录代码 :
BML-P601-0500
产品名称 :
NF-κB SN50M cell permeable control peptide
产品类型 :
多肽
规格 :
0.5毫克
Pubmed号列表 :
26100633, 22027835, 14645003, 7782278
产品描述 :
Inactive control peptide for the cell-permeable NF-κB inhibitory peptide SN50. Contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NF-κB p50 linked to the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF), except this control peptide has Lys363 to Asn and Arg364 to Gly. In mouse endothelial LE-II cells induced with LPS, SN50M peptide had no measureable effect on NF-κB translocation at 50 µg/ml. In human monocytic THP-1 cells induced by LPS or TNFα, there was slight inhibition of nuclear transport at 100 µg/ml. Sold under license from Vanderbilt University.
纯度 :
≥97%(HPLC)
缓冲液 :
Lyophilized. Counter Ion: Trifluoroacetate salt.
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。