产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
蛋白
产品名称 :
基质金属蛋白酶-2(催化域)(人类),(重组)
目录 :
BML-SE237-0010
规格 :
10微克
更多信息或购买 :
Enzo Life Sciences 产品网页
文章摘录数: 6
参考文献
Edkins T, Alhadeff J, Kwok V, Kalensky C, Rock M, Vidmar T, et al. Development and validation of novel enzyme activity methods to assess inhibition of matrix metalloproteinases (MMPs) in human serum by antibodies against enzyme therapeutics. J Pharm Biomed Anal. 2012;70:408-14 pubmed 出版商
Harney A, Sole L, Meade T. Kinetics and thermodynamics of irreversible inhibition of matrix metalloproteinase 2 by a Co(III) Schiff base complex. J Biol Inorg Chem. 2012;17:853-60 pubmed 出版商
Jabaiah A, Daugherty P. Directed evolution of protease beacons that enable sensitive detection of endogenous MT1-MMP activity in tumor cell lines. Chem Biol. 2011;18:392-401 pubmed 出版商
Ali M, Cho W, Hudson B, Kassiri Z, Granzier H, Schulz R. Titin is a target of matrix metalloproteinase-2: implications in myocardial ischemia/reperfusion injury. Circulation. 2010;122:2039-47 pubmed 出版商
Dixon J, Gaillard W, Rivers W, Koval C, Stroud R, Mukherjee R, et al. Heterogeneity in MT1-MMP activity with ischemia-reperfusion and previous myocardial infarction: relation to regional myocardial function. Am J Physiol Heart Circ Physiol. 2010;299:H1947-58 pubmed 出版商
Skarja G, Brown A, Ho R, May M, Sefton M. The effect of a hydroxamic acid-containing polymer on active matrix metalloproteinases. Biomaterials. 2009;30:1890-7 pubmed 出版商
产品信息
产品编号 :
BML-SE237
目录代码 :
BML-SE237-0010
产品名称 :
基质金属蛋白酶-2(催化域)(人类),(重组)
产品类型 :
蛋白
规格 :
10微克
Pubmed号列表 :
22854133, 22729838, 21439484, 21041693, 20935147, 19147221
产品描述 :
Represents a naturally occurring active form of MMP-2 which lacks the C-terminal hemopexin domain. MMPs lacking this domain cannot cleave native collagens; however, activity toward other targets such as gelatin, casein, or peptide substrates is unaffected.
别名 :
基质金属蛋白酶2, 明胶酶a, 72kDa的IV型胶原酶
纯度 :
≥90%(十二烷基磺酸钠-PAGE)
缓冲液 :
Liquid. In 50mM TRIS-HCl, pH 7.5, containing 300mM NaCl, 5mM CaCl2, 20µM ZnCl2, 0.05% Brij-35 and 20% glycerol.
用途 :
Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors.
储存 :
-80°C
更多信息或购买 :
Enzo Life Sciences 产品网页
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。