产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
化学品
产品名称 :
Latrunculin B
目录 :
BML-T110-0001
规格 :
1毫克
更多信息或购买 :
Enzo Life Sciences 产品网页
文章摘录数: 14
参考文献
Ho W, Tai Y, Chang J, Liang J, Tyan S, Chen S, et al. The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy. Autophagy. 2019;15:827-842 pubmed 出版商
Yang J, Bhattacharya S, West Foyle H, Hung C, Wu T, Iglesias P, et al. Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation. Nat Commun. 2018;9:4673 pubmed 出版商
Ege N, Dowbaj A, Jiang M, Howell M, Hooper S, Foster C, et al. Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export. Cell Syst. 2018;6:692-708.e13 pubmed 出版商
Zhu C, Ganguly A, Baskin T, McClosky D, Anderson C, Foster C, et al. The fragile Fiber1 kinesin contributes to cortical microtubule-mediated trafficking of cell wall components. Plant Physiol. 2015;167:780-92 pubmed 出版商
Stanganello E, Hagemann A, Mattes B, Sinner C, Meyen D, Weber S, et al. Filopodia-based Wnt transport during vertebrate tissue patterning. Nat Commun. 2015;6:5846 pubmed 出版商
Allam R, Darisipudi M, Tschopp J, Anders H. Histones trigger sterile inflammation by activating the NLRP3 inflammasome. Eur J Immunol. 2013;43:3336-42 pubmed 出版商
Arif E, Wagner M, Johnstone D, Wong H, George B, Pruthi P, et al. Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membrane. Mol Cell Biol. 2011;31:2134-50 pubmed 出版商
Minamide L, Maiti S, Boyle J, Davis R, Coppinger J, Bao Y, et al. Isolation and characterization of cytoplasmic cofilin-actin rods. J Biol Chem. 2010;285:5450-60 pubmed 出版商
Cha B, Kenworthy A, Murtazina R, Donowitz M. The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1/2, but is dependent on an intact actin cytoskeleton as determined by FRAP. J Cell Sci. 2004;117:3353-65 pubmed
Wakatsuki T, Schwab B, Thompson N, Elson E. Effects of cytochalasin D and latrunculin B on mechanical properties of cells. J Cell Sci. 2001;114:1025-36 pubmed
Spector I, Shochet N, Kashman Y, Groweiss A. Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells. Science. 1983;219:493-5 pubmed
Schatten G, Schatten H, Spector I, Cline C, Paweletz N, Simerly C, et al. Latrunculin inhibits the microfilament-mediated processes during fertilization, cleavage and early development in sea urchins and mice. Exp Cell Res. 1986;166:191-208 pubmed
Coue M, Brenner S, Spector I, Korn E. Inhibition of actin polymerization by latrunculin A. FEBS Lett. 1987;213:316-8 pubmed
de Oliveira C, Mantovani B. Latrunculin A is a potent inhibitor of phagocytosis by macrophages. Life Sci. 1988;43:1825-30 pubmed
产品信息
产品编号 :
BML-T110
目录代码 :
BML-T110-0001
产品名称 :
Latrunculin B
产品类型 :
Biochemical
规格 :
1毫克
Pubmed号列表 :
25646318, 25556612, 23964013, 20022956, 15226406, 11181185, 6681676, 3743654, 3556584, 3200109
产品描述 :
Structurally unique marine toxin. Actin filament modulator. 10- to 100-fold more potent than cytochalasins. Whereas cytochalasin D (Prod. No. BML-T109) induces dissolution of F-actin and stress fiber contraction in fibroblasts in culture, latrunculin B causes a shortening and thickening of stress fibers. Effects on N1E-115 cells (mouse neuroblastoma) at concentrations as low as 90nM (NI43T3 cells, 0.9µM). Maximum effects at 2.5µM. Slowly inactivated by fetal bovine serum. Inhibition of cofilin-actin binding (ED50~50µM)
纯度 :
≥98%(HPLC)
储存 :
-20°C
更多信息或购买 :
Enzo Life Sciences 产品网页
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始，Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司，为生命科学研究各个领域提供更全面的试剂产品。比如，肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究，都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。