产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
化学品
产品名称 :
Mycalolide B
目录 :
BML-T123-0020
规格 :
20微克
更多信息或购买 :
文章摘录数: 9
参考文献
Sasaki H, Ozaki H, Karaki H, Nonomura Y. Actin filaments play an essential role for transport of nascent HIV-1 proteins in host cells. Biochem Biophys Res Commun. 2004;316:588-93 pubmed
Takakuwa R, Kokai Y, Kojima T, Akatsuka T, Tobioka H, Sawada N, et al. Uncoupling of gate and fence functions of MDCK cells by the actin-depolymerizing reagent mycalolide B. Exp Cell Res. 2000;257:238-44 pubmed
Wada S, Matsunaga S, Saito S, Fusetani N, Watabe S. Actin-binding specificity of marine macrolide toxins, mycalolide B and kabiramide D. J Biochem. 1998;123:946-52 pubmed
Saito S, Watabe S, Ozaki H, Kobayashi M, Suzuki T, Kobayashi H, et al. Actin-depolymerizing effect of dimeric macrolides, bistheonellide A and swinholide A. J Biochem. 1998;123:571-8 pubmed
Sugidachi A, Ogawa T, Asai F, Saito S, Ozaki H, Fusetani N, et al. Inhibition of rat platelet aggregation by mycalolide-B, a novel inhibitor of actin polymerization with a different mechanism of action from cytochalasin-D. Thromb Haemost. 1998;79:614-9 pubmed
Saito S, Karaki H. A family of novel actin-inhibiting marine toxins. Clin Exp Pharmacol Physiol. 1996;23:743-6 pubmed
Watabe S, Wada S, Saito S, Matsunaga S, Fusetani N, Ozaki H, et al. Cellular changes of rat embryonic fibroblasts by an actin-polymerization inhibitor, bistheonellide A, from a marine sponge. Cell Struct Funct. 1996;21:199-212 pubmed
Hori M, Saito S, Shin Y, Ozaki H, Fusetani N, Karaki H. Mycalolide-B, a novel and specific inhibitor of actomyosin ATPase isolated from marine sponge. FEBS Lett. 1993;322:151-4 pubmed
Saito S, Watabe S, Ozaki H, Fusetani N, Karaki H. Mycalolide B, a novel actin depolymerizing agent. J Biol Chem. 1994;269:29710-4 pubmed
产品信息
产品编号 :
BML-T123
目录代码 :
BML-T123-0020
产品名称 :
Mycalolide B
产品类型 :
Biochemical
规格 :
20微克
Pubmed号列表 :
15020258, 10837137, 9562630, 9538245, 9531051, 8886501, 8853557, 8482383, 7961961
产品描述 :
Mycalolide B is a novel marine natural product which binds to actin in a 1:1 molar ratio (Kd=13-20 nM). It selectively and completely depolymerizes F-actin to G-actin via a mechanism distinct from that of the cytochalasins. Unlike cytochalasins, it inhibits actin-activated Mg2+-ATPase from rabbit skeletal muscle.
纯度 :
≥98%(HPLC)
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。