产品简要
公司名称 :
Enzo Life Sciences
其他品牌 :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
产品类型 :
化学品
产品名称 :
N-Arachidonoyl-serotonin
目录 :
BML-VR106-0050
规格 :
50毫克
更多信息或购买 :
文章摘录数: 4
参考文献
Maione S, De Petrocellis L, de Novellis V, Moriello A, Petrosino S, Palazzo E, et al. Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors. Br J Pharmacol. 2007;150:766-81 pubmed
D Argenio G, Valenti M, Scaglione G, Cosenza V, Sorrentini I, Di Marzo V. Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. FASEB J. 2006;20:568-70 pubmed
de Lago E, Petrosino S, Valenti M, Morera E, Ortega Gutierrez S, Fernandez Ruiz J, et al. Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels. Biochem Pharmacol. 2005;70:446-52 pubmed
Bisogno T, Melck D, De Petrocellis L, Bobrov MYu -, Gretskaya N, Bezuglov V, et al. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. Biochem Biophys Res Commun. 1998;248:515-22 pubmed
产品信息
产品编号 :
BML-VR106
目录代码 :
BML-VR106-0050
产品名称 :
N-Arachidonoyl-serotonin
产品类型 :
Biochemical
规格 :
50毫克
Pubmed号列表 :
17279090, 16403786, 15963472, 9703957
产品描述 :
Unnatural fatty acid-neurotransmitter conjugate. Potent TRPV1 antagonist (IC50=40nM). Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.6mM). Enhances levels of anandamide and 2-AG in vivo. Displays analgesic activity in both acute and chronic peripheral pain models but shows little efficacy in an inflammatory bowel disease model.
纯度 :
≥98%(TLC)
储存 :
-20°C
更多信息或购买 :
公司信息
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
techserv-usa@enzolifesciences.com
https://www.enzolifesciences.com
1-800-942-0430
公司总部: 美国
自2007年始,Enzo Life Sciences先后合并ALEXIS Biochemicals、BIOMOL International等公司,为生命科学研究各个领域提供更全面的试剂产品。比如,肿瘤、细胞死亡、表观遗传、基因组学、免疫学、神经科学、信号转导及泛素和蛋白酶体等领域研究,都可以在Enzo Life Sciences中找到相应抗体、酶、蛋白、小分子抑制剂、产品文库及检测kit等产品。