产品简要
公司名称 :
Epigentek
产品类型 :
抗体
产品名称 :
Histone H3R26 Dimethyl Asymmetric (H3R26me2a) Polyclonal Antibody
目录 :
A-3707-100
规格 :
100微升
价格 :
411.00美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
多克隆
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
产品信息
Catalog# :
A-3707
Part # :
A-3707-100
2022价格(美国) :
411.00美元
产品描述(产品名称) :
Histone H3R26 Dimethyl Asymmetric (H3R26me2a) Polyclonal Antibody
规格 :
100微升
宿主 :
Antigen (Uniprot Accession, Gene or prot ... :
Histone H3R26 Asymmetric Dimethyl
共轭标签 :
未共轭
克隆性 :
多克隆
物种/反应物种 :
Human, Mouse, Rat, Broad Range
应用 :
免疫印迹, IF
抗体亚型 :
IgG
免疫原 :
Synthetic Peptide of Human Asymmetric DiMethyl-Histone H3-R26
运输温度 :
Shipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.
UniProt数据库编号 :
P68431
基因 :
H3R26me2a
储存缓冲液 :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯度 :
亲和纯化
别称 :
H3R26me2a, HIST1H3J, H3/j, H3FJ, 组蛋白H3.1, 组蛋白H3/a, 组蛋白H3/b, 组蛋白H3/c, 组蛋白H3/d, 组蛋白H3/f, 组蛋白H3/h, 组蛋白H3/I, 组蛋白H3/j, 组蛋白H3/k, 组蛋白H3/l, HIST3H3, H3精氨酸26 me2a
背景 :
Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. The amino-terminal tails of core histones undergo various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination. These modifications occur in response to various stimuli and have a direct effect on the accessibility of chromatin to transcription factors and, therefore, gene expression. In most species, histone H2B is primarily acetylated at Lys5, 12, 15, and 20. Histone H3 is primarily acetylated at Lys9, 14, 18, 23, 27, and 56. Acetylation of H3 at Lys9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10, Ser28, and Thr11 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis. Phosphorylation at Thr3 of histone H3 is highly conserved among many species and is catalyzed by the kinase haspin. Immunostaining with phospho-specific antibodies in mammalian cells reveals mitotic phosphorylation at Thr3 of H3 in prophase and its dephosphorylation during anaphase.
更多信息或购买 :
公司信息
Epigentek
110 Bi County Blvd. Ste 122
Farmingdale, NY 11735
support@epigentek.com
http://www.epigentek.com
1-631-755-0888