抗体

CDK5多克隆抗体

A70464-100

100微升

370.00美元

多克隆

domestic rabbit

未共轭

多克隆

人类, 小鼠, 大鼠

免疫印迹, 免疫细胞化学, 免疫沉淀

A70464-100

370.00美元

CDK5多克隆抗体

100微升

兔

CDK5

未共轭

多克隆

人类, 小鼠, 大鼠

免疫印迹, IF, 免疫沉淀

IgG

Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human CDK5 (NP_004926.1).

Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Q00535

CDK5

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

亲和纯化

CDK5;LIS7;PSSALRE;细胞周期蛋白依赖激酶5

This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.