产品简要
信息索取 :
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
磷酸酶张力蛋白同源基因抗体
目录 :
GTX101025
规格 :
100.00μl
价格 :
299美元
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
GeneTex 产品网页
文章摘录数: 3
已发表的文献中的应用方法／种属／稀释度参考文献
  • 免疫印迹; 人类; 图 4
Chen N, Chyau C, Lee Y, Tseng H, Chou F. Promotion of mitotic catastrophe via activation of PTEN by paclitaxel with supplement of mulberry water extract in bladder cancer cells. Sci Rep. 2016;6:20417 pubmed 出版商
Kim J, Kim J, Kim J, Kim S, Chung H, Park C. HOXA10 is associated with temozolomide resistance through regulation of the homologous recombinant DNA repair pathway in glioblastoma cell lines. Genes Cancer. 2014;5:165-74 pubmed
Huang A, Kao Y, Toh S, Lin P, Chou C, Hu H, et al. UBE2M-mediated p27(Kip1) degradation in gemcitabine cytotoxicity. Biochem Pharmacol. 2011;82:35-42 pubmed 出版商
图像
图像 1 :
GeneTex GTX101025 图像 1
PTEN antibody detects PTEN protein by western blot analysis. Various whole cell extracts (30 ?g) were separated by 10% SDS-PAGE, and the membrane was blotted with PTEN antibody (GTX101025) diluted at a dilution of 1:500.
图像 2 :
GeneTex GTX101025 图像 2
PTEN antibody detects PTEN protein at cytosol on H1299 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded H1299 xenograft. PTEN antibody (GTX101025) dilution: 1:200.
图像 3 :
GeneTex GTX101025 图像 3
Sample (30 ug of whole cell lysate) A: NIH-3T3 10% SDS PAGE GTX101025 diluted at 1:500
产品信息
目录号 :
GTX101025
产品名称 :
磷酸酶张力蛋白同源基因抗体
宿主物种 :
兔
克隆性 :
多克隆
产品类型 :
一抗
规格 :
100.00μl
标价 :
299美元
Pubmed号列表 :
21477582,25061500
产品描述 :
Rabbit Polyclonal antibody to PTEN (phosphatase and tensin homolog)
交叉活性 :
Hu, Ms, Rat
背景 :
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. [provided by RefSeq]
免疫原 :
Recombinant protein encompassing a sequence within the center region of human PTEN. The exact sequence is proprietary.
缓冲液 :
1XPBS, 1% BSA, 20% 甘油(pH7)。 0.01% 硫柳汞被添加a防腐剂
用途 :
免疫细胞化学/IF, 免疫组化-P, 免疫印迹
浓度 :
1毫克/毫升
一般参考 :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
图像Legend_4 :
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using PTEN(GTX101025) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with GTX11304 (Red) at 1:2000.
图像Legend_5 :
Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE GTX101025 diluted at 1:1000
图像Legend_6 :
PTEN antibody detects PTEN protein at cytosol and nucleus on mouse middle brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse middle brain. PTEN antibody (GTX101025) dilution: 1:500.
图像Legend_7 :
PTEN antibody detects PTEN protein at cytosol and nucleus on rat middle brain by immunohistochemical analysis. Sample: Paraffin-embedded rat middle brain. PTEN antibody (GTX101025) dilution: 1:500.
更多信息或购买 :
GeneTex 产品网页
公司信息
GeneTex
2456 Alton Pkwy
Irvine, CA92606
support@genetex.com
www.genetex.com
886-3-6208988
公司总部: 美国