产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
SHP2抗体
目录 :
GTX101062
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
反应物种 :
人类
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文章摘录数: 1
产品信息
目录代码 :
GTX101062
产品名称 :
SHP2抗体
宿主物种 :
兔
克隆性 :
多克隆
产品类型 :
一抗
Pubmed号列表 :
28367723
背景 :
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq]
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公司信息
GeneTex