产品简要
公司名称 :
GeneTex
产品类型 :
抗体
产品名称 :
NFkB p65抗体
目录 :
GTX102090
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
人类
更多信息或购买 :
文章摘录数: 22
参考文献
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Gerzanich V, Kwon M, Woo S, Ivanov A, Simard J. SUR1-TRPM4 channel activation and phasic secretion of MMP-9 induced by tPA in brain endothelial cells. PLoS ONE. 2018;13:e0195526 pubmed 出版商
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Chamard Jovenin C, Thiebaut C, Chesnel A, Bresso E, Morel C, Smail Tabbone M, et al. Low-Dose Alkylphenol Exposure Promotes Mammary Epithelium Alterations and Transgenerational Developmental Defects, But Does Not Enhance Tumorigenic Behavior of Breast Cancer Cells. Front Endocrinol (Lausanne). 2017;8:272 pubmed 出版商
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Wu P, Lyu J, Liu Y, Chien T, Hsu H, Wen K, et al. Fisetin Regulates Nrf2 Expression and the Inflammation-Related Signaling Pathway to Prevent UVB-Induced Skin Damage in Hairless Mice. Int J Mol Sci. 2017;18: pubmed 出版商
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Gerzanich V, Makar T, Guda P, Kwon M, Stokum J, Woo S, et al. Salutary effects of glibenclamide during the chronic phase of murine experimental autoimmune encephalomyelitis. J Neuroinflammation. 2017;14:177 pubmed 出版商
Huang Y, Tsai M, Hsieh P, Shih J, Wang T, Wang Y, et al. Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of ERK and NF-kappaB signaling. Toxicol Appl Pharmacol. 2017;329:128-139 pubmed 出版商
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产品信息
目录代码 :
GTX102090
产品名称 :
NFkB p65抗体
宿主物种 :
克隆性 :
多克隆
产品类型 :
一抗
Pubmed号列表 :
25732306,26133168,26743692,27400716,27858493,28301550,28558962,28558037,28533271,28865458,24039598,28971991,28929255,28994699,29109696,29084133,29058550,29058549,29142311,29396513,29617457
背景 :
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM]
更多信息或购买 :
公司信息
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